(33 nodes) Active ion transmembrane transporter activity network (Streptomyces nodosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AJE38752.1	Spermidine/putrescine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (358 aa)
	AJE39701.1	Spermidine/putrescine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (350 aa)
	metN	Methionine ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (344 aa)
	AJE44444.1	Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (793 aa)
	AJE43012.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (364 aa)
	potA	Spermidine/putrescine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (388 aa)
	AJE42762.1	Dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa)
	fbpC	Iron ABC transporter ATP-binding protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system. (344 aa)
	atpD	ATP F0F1 synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (478 aa)
	atpA	ATP synthase F0F1 subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (530 aa)
	pstB-3	Phosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (272 aa)
	pstB-2	Phosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (283 aa)
	hppA	Potassium transporter; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. (800 aa)
	pstB	Phosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (258 aa)
	AJE41131.1	PTS lactose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (700 aa)
	AJE41125.1	Potassium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
	AJE40763.1	Carbonate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (758 aa)
	AJE40346.1	Cytochrome C oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
	AJE40345.1	Cytochrome C oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (578 aa)
	AJE40344.1	Cytochrome C oxidase subunit IV; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family. (132 aa)
	AJE40341.1	Cytochrome B561; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
	AJE40340.1	Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
	AJE40338.1	Ubiquinol-cytochrome c reductase cytochrome b subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (545 aa)
	AJE40183.1	Ionic transporter y4hA; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
	AJE39100.1	Cytochrome C oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
	AJE39973.1	Cytochrome C oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (562 aa)
	AJE39147.1	Phosphonate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
	AJE39148.1	Phosphonate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (384 aa)
	AJE39223.1	Cytochrome C oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (566 aa)
	AJE39367.1	MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (570 aa)
	kdpC	Potassium-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (221 aa)
	kdpB	Potassium transporter KtrB; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (699 aa)
	kdpA	Potassium-transporting ATPase subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (554 aa)

Your Current Organism:

Streptomyces nodosus

NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJE38752.1	AJE39147.1	SNOD_00575	SNOD_03195	Spermidine/putrescine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Phosphonate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.887
AJE38752.1	AJE39148.1	SNOD_00575	SNOD_03200	Spermidine/putrescine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Phosphonate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.452
AJE38752.1	AJE39701.1	SNOD_00575	SNOD_06490	Spermidine/putrescine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Spermidine/putrescine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.416
AJE38752.1	fbpC	SNOD_00575	SNOD_23940	Spermidine/putrescine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Iron ABC transporter ATP-binding protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.	0.443
AJE38752.1	potA	SNOD_00575	SNOD_24050	Spermidine/putrescine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Spermidine/putrescine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.	0.412
AJE39100.1	AJE40338.1	SNOD_02910	SNOD_10010	Cytochrome C oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ubiquinol-cytochrome c reductase cytochrome b subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.992
AJE39100.1	AJE40340.1	SNOD_02910	SNOD_10020	Cytochrome C oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.903
AJE39100.1	AJE40341.1	SNOD_02910	SNOD_10025	Cytochrome C oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cytochrome B561; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
AJE39100.1	AJE40344.1	SNOD_02910	SNOD_10040	Cytochrome C oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cytochrome C oxidase subunit IV; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family.	0.941
AJE39100.1	AJE40346.1	SNOD_02910	SNOD_10050	Cytochrome C oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cytochrome C oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
AJE39100.1	atpA	SNOD_02910	SNOD_22760	Cytochrome C oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP synthase F0F1 subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.	0.528
AJE39147.1	AJE38752.1	SNOD_03195	SNOD_00575	Phosphonate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Spermidine/putrescine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.887
AJE39147.1	AJE39148.1	SNOD_03195	SNOD_03200	Phosphonate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphonate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.996
AJE39147.1	AJE39701.1	SNOD_03195	SNOD_06490	Phosphonate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Spermidine/putrescine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.827
AJE39147.1	AJE43012.1	SNOD_03195	SNOD_25490	Phosphonate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.625
AJE39147.1	fbpC	SNOD_03195	SNOD_23940	Phosphonate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Iron ABC transporter ATP-binding protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.	0.859
AJE39147.1	potA	SNOD_03195	SNOD_24050	Phosphonate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Spermidine/putrescine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.	0.868
AJE39148.1	AJE38752.1	SNOD_03200	SNOD_00575	Phosphonate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Spermidine/putrescine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.452
AJE39148.1	AJE39147.1	SNOD_03200	SNOD_03195	Phosphonate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Phosphonate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
AJE39148.1	AJE39701.1	SNOD_03200	SNOD_06490	Phosphonate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Spermidine/putrescine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.424

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