STRINGSTRING
AJE43170.1 AJE43170.1 cmk cmk AJE39964.1 AJE39964.1 AJE39963.1 AJE39963.1 AJE39931.1 AJE39931.1 AJE39912.1 AJE39912.1 apt apt AJE39751.1 AJE39751.1 nusB nusB pyrB pyrB pyrC pyrC AJE39725.1 AJE39725.1 carA carA carB carB pyrD pyrD gmk gmk rpoZ rpoZ AJE39718.1 AJE39718.1 priA priA AJE39707.1 AJE39707.1 AJE39685.1 AJE39685.1 AJE39656.1 AJE39656.1 dinB dinB AJE39635.1 AJE39635.1 AJE39560.1 AJE39560.1 AJE39511.1 AJE39511.1 ligB ligB AJE39486.1 AJE39486.1 AJE39443.1 AJE39443.1 AJE39383.1 AJE39383.1 AJE39380.1 AJE39380.1 AJE39308.1 AJE39308.1 AJE39290.1 AJE39290.1 AJE39271.1 AJE39271.1 AJE39244.1 AJE39244.1 AJE39134.1 AJE39134.1 purU-2 purU-2 folD folD AJE38788.1 AJE38788.1 AJE38782.1 AJE38782.1 AJE38773.1 AJE38773.1 AJE38697.1 AJE38697.1 rpoC rpoC adk adk rpoA-2 rpoA-2 glmM glmM coaA coaA AJE42071.1 AJE42071.1 guaB guaB AJE42073.1 AJE42073.1 guaA guaA AJE42102.1 AJE42102.1 AJE42107.1 AJE42107.1 purN purN purH purH folD-2 folD-2 AJE42149.1 AJE42149.1 AJE42178.1 AJE42178.1 add add AJE42188.1 AJE42188.1 AJE42189.1 AJE42189.1 AJE42216.1 AJE42216.1 AJE42236.1 AJE42236.1 greA greA AJE42264.1 AJE42264.1 AJE42366.1 AJE42366.1 AJE42430.1 AJE42430.1 AJE42436.1 AJE42436.1 AJE42451.1 AJE42451.1 AJE42507.1 AJE42507.1 rho rho atpB atpB atpE atpE atpF atpF atpH atpH atpA atpA atpG atpG atpD atpD atpC atpC AJE42555.1 AJE42555.1 ackA ackA AJE42581.1 AJE42581.1 coaD coaD AJE42742.1 AJE42742.1 pyrH pyrH nusA nusA AJE42812.1 AJE42812.1 thyX thyX AJE42848.1 AJE42848.1 AJE42892.1 AJE42892.1 sigA sigA tdk tdk dut dut AJE42978.1 AJE42978.1 AJE43030.1 AJE43030.1 nadD nadD ndk ndk AJE40710.1 AJE40710.1 AJE40743.1 AJE40743.1 AJE40833.1 AJE40833.1 AJE40894.1 AJE40894.1 AJE40895.1 AJE40895.1 AJE40919.1 AJE40919.1 AJE40925.1 AJE40925.1 AJE40980.1 AJE40980.1 manA manA AJE41007.1 AJE41007.1 purE purE purK purK AJE41019.1 AJE41019.1 glmU glmU prs prs AJE41126.1 AJE41126.1 AJE41135.1 AJE41135.1 AJE41152.1 AJE41152.1 rpoA rpoA purU purU AJE41314.1 AJE41314.1 AJE41349.1 AJE41349.1 AJE41373.1 AJE41373.1 AJE41401.1 AJE41401.1 purM purM purF purF purQ purQ purS purS purC purC purD purD upp upp AJE41450.1 AJE41450.1 AJE41451.1 AJE41451.1 AJE41465.1 AJE41465.1 serS serS AJE41523.1 AJE41523.1 AJE41528.1 AJE41528.1 AJE41545.1 AJE41545.1 AJE41558.1 AJE41558.1 recF recF AJE41600.1 AJE41600.1 AJE41611.1 AJE41611.1 dcd dcd AJE43200.1 AJE43200.1 AJE43206.1 AJE43206.1 AJE43332.1 AJE43332.1 AJE43359.1 AJE43359.1 AJE43382.1 AJE43382.1 AJE43468.1 AJE43468.1 AJE43491.1 AJE43491.1 AJE43518.1 AJE43518.1 AJE43529.1 AJE43529.1 AJE43614.1 AJE43614.1 AJE44480.1 AJE44480.1 AJE44443.1 AJE44443.1 AJE44308.1 AJE44308.1 AJE44272.1 AJE44272.1 nadK nadK AJE44131.1 AJE44131.1 add-2 add-2 AJE44083.1 AJE44083.1 AJE44040.1 AJE44040.1 rho-2 rho-2 AJE43950.1 AJE43950.1 AJE43868.1 AJE43868.1 AJE43670.1 AJE43670.1 AJE43652.1 AJE43652.1 AJE43626.1 AJE43626.1 AJE43625.1 AJE43625.1 AJE41674.1 AJE41674.1 pyrE pyrE kynU kynU purA purA AJE41726.1 AJE41726.1 acsA acsA AJE41773.1 AJE41773.1 AJE41777.1 AJE41777.1 AJE41803.1 AJE41803.1 AJE41824.1 AJE41824.1 coaX coaX AJE41838.1 AJE41838.1 AJE41863.1 AJE41863.1 AJE41900.1 AJE41900.1 AJE41977.1 AJE41977.1 nusG nusG rpoB rpoB AJE40617.1 AJE40617.1 dnaG dnaG AJE40563.1 AJE40563.1 AJE40511.1 AJE40511.1 AJE40434.1 AJE40434.1 nadA nadA AJE40271.1 AJE40271.1 AJE40264.1 AJE40264.1 polA polA AJE40190.1 AJE40190.1 ppnK ppnK pyrG pyrG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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AJE43170.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (559 aa)
cmkCytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
AJE39964.1DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA polymerase type-C family. DnaE2 subfamily. (1163 aa)
AJE39963.1DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA polymerase type-Y family. (324 aa)
AJE39931.1Serine-threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)
AJE39912.1Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (581 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (179 aa)
AJE39751.1GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (843 aa)
nusBAntitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (144 aa)
pyrBAspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (343 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (428 aa)
AJE39725.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (385 aa)
carBCarbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (1102 aa)
pyrDDiguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (368 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (177 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (90 aa)
AJE39718.1Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (400 aa)
priAPrimosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (719 aa)
AJE39707.1Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
AJE39685.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
AJE39656.1acetoacetyl-CoA synthetase; AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (655 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (483 aa)
AJE39635.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
AJE39560.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (480 aa)
AJE39511.1DNA mismatch repair protein MutT; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
ligBATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (512 aa)
AJE39486.1Epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
AJE39443.1RNA polymerase sigma factor SigL; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa)
AJE39383.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
AJE39380.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
AJE39308.1RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (271 aa)
AJE39290.1RNA polymerase sigma 70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (297 aa)
AJE39271.1Flavoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
AJE39244.1ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
AJE39134.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa)
purU-2Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (302 aa)
folD5,10-methylene-tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa)
AJE38788.1RNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (210 aa)
AJE38782.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
AJE38773.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
AJE38697.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (175 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1306 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (220 aa)
rpoA-2DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (340 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (452 aa)
coaAPantothenate kinase; Catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
AJE42071.1RNA polymerase sigma factor SigD; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa)
guaBInosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (501 aa)
AJE42073.1Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (529 aa)
AJE42102.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (491 aa)
AJE42107.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (212 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (528 aa)
folD-2Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
AJE42149.1RNA polymerase sigma70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (225 aa)
AJE42178.1RNA polymerase sigma70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (334 aa)
addAdenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (383 aa)
AJE42188.1RNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (254 aa)
AJE42189.1Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
AJE42216.1Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
AJE42236.1RNA polymerase sigma70; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
greATranscription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (166 aa)
AJE42264.1RNA polymerase sigma24 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (171 aa)
AJE42366.1RNA polymerase sigma factor SigE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (218 aa)
AJE42430.1RNA polymerase sigma factor RpoE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (227 aa)
AJE42436.1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (340 aa)
AJE42451.1RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (270 aa)
AJE42507.1ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (659 aa)
atpBATP synthase F0F1 subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (256 aa)
atpEATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (80 aa)
atpFATP synthase F0F1 subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (183 aa)
atpHATP synthase F0F1 subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (271 aa)
atpAATP synthase F0F1 subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (530 aa)
atpGATP synthase F0F1 subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (305 aa)
atpDATP F0F1 synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (478 aa)
atpCATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (124 aa)
AJE42555.1ATP/GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (402 aa)
AJE42581.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (696 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (159 aa)
AJE42742.1RNA polymerase sigma70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (258 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (252 aa)
nusATranscription elongation factor NusA; Participates in both transcription termination and antitermination. (331 aa)
AJE42812.1Riboflavin kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (316 aa)
thyXFAD-dependent thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (246 aa)
AJE42848.1Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (181 aa)
AJE42892.1Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (961 aa)
sigARNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (510 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (171 aa)
AJE42978.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
AJE43030.1PaaX family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (220 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (137 aa)
AJE40710.1RNA polymerase sigma24 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (198 aa)
AJE40743.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
AJE40833.1Peptidase M6; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
AJE40894.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (433 aa)
AJE40895.1Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
AJE40919.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family. (189 aa)
AJE40925.1RNA polymerase sigma factor SigL; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (196 aa)
AJE40980.1acetyl-CoA carboxyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
manAMannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
AJE41007.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (172 aa)
purKPhosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (391 aa)
AJE41019.1RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (308 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (482 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (324 aa)
AJE41126.1Purine nucleoside phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (277 aa)
AJE41135.1RNA polymerase sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (332 aa)
AJE41152.1RNA polymerase sigma24 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (381 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (338 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (293 aa)
AJE41314.1CarD family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
AJE41349.1Fatty acid-binding protein; May play a role in the intracellular transport of hydrophobic ligands. (191 aa)
AJE41373.1RNA polymerase sigma24 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (179 aa)
AJE41401.1ECF subfamily RNA polymerase sigma-24 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (672 aa)
purMPhosphoribosylaminoimidazole synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (508 aa)
purQPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (226 aa)
purSPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (87 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (299 aa)
purDPhosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (418 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (211 aa)
AJE41450.1RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (304 aa)
AJE41451.1RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (303 aa)
AJE41465.1RNA polymerase sigma24 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (425 aa)
AJE41523.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
AJE41528.1Helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (491 aa)
AJE41545.1RNA polymerase sigma factor SigM; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (240 aa)
AJE41558.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (376 aa)
recFRecombinase RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (373 aa)
AJE41600.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
AJE41611.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
dcdDeoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (191 aa)
AJE43200.1RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa)
AJE43206.1Phenylhydantoinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
AJE43332.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
AJE43359.1RNA polymerase sigma24 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (314 aa)
AJE43382.1RNA polymerase sigma-70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (171 aa)
AJE43468.16-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
AJE43491.1ATP-grasp domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
AJE43518.1ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
AJE43529.1Plasmid stabilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa)
AJE43614.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
AJE44480.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
AJE44443.1Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
AJE44308.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
AJE44272.1RNA polymerase sigma 70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (314 aa)
nadKInorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (354 aa)
AJE44131.1Fructose transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
add-2Adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (356 aa)
AJE44083.1RNA polymerase sigma24 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (288 aa)
AJE44040.1RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (199 aa)
rho-2Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (379 aa)
AJE43950.1Phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
AJE43868.1RNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (211 aa)
AJE43670.1dTDP-4-dehydrorhamnose 3,5-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
AJE43652.1RNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (184 aa)
AJE43626.1RNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (221 aa)
AJE43625.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)
AJE41674.1Phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (175 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (400 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (427 aa)
AJE41726.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
AJE41773.1DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
AJE41777.13'-5' exonuclease; Similar to DNA polymerase I; lacks 5'-3' exonuclease domain; Derived by automated computational analysis using gene prediction method: Protein Homology. (565 aa)
AJE41803.1Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (186 aa)
AJE41824.1Nicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (325 aa)
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (265 aa)
AJE41838.1RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (179 aa)
AJE41863.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (258 aa)
AJE41900.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
AJE41977.1Adenine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
nusGTranscription termination/antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (269 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1161 aa)
AJE40617.1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (330 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (634 aa)
AJE40563.1Hypothetical protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (393 aa)
AJE40511.1Flavoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
AJE40434.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (163 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (394 aa)
AJE40271.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
AJE40264.1DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1179 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (907 aa)
AJE40190.1Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
ppnKInorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (301 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (562 aa)
Your Current Organism:
Streptomyces nodosus
NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus
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