(70 nodes) Vesicle network (Streptomyces nodosus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AJE39921.1	Zinc-binding alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
	AJE38713.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
	AJE38864.1	NADP oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
	AJE38896.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
	AJE38904.1	Amino acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
	AJE38977.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
	AJE39085.1	Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
	AJE39209.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
	dnaK	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (619 aa)
	AJE39373.1	2,3-butanediol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
	AJE39378.1	Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa)
	AJE39406.1	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. (128 aa)
	AJE39477.1	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
	AJE39478.1	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
	AJE39589.1	Cation diffusion facilitator family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
	AJE39593.1	Cation diffusion facilitator family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (359 aa)
	AJE39644.1	Photosystem reaction center subunit H; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
	AJE39699.1	Carbon-nitrogen hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
	AJE39707.1	Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
	AJE39820.1	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
	dnaK2	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (625 aa)
	AJE43296.1	Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (608 aa)
	AJE43344.1	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
	AJE43434.1	NADP oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
	AJE43592.1	Metallo-beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
	AJE43645.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
	tdh	L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (342 aa)
	AJE43688.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
	AJE43825.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
	AJE44143.1	Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (642 aa)
	AJE44214.1	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
	AJE44235.1	3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
	AJE44368.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
	AJE40008.1	HNH nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
	AJE40107.1	Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
	AJE40124.1	Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
	AJE40131.1	HNH endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
	AJE40161.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
	AJE40223.1	Amino acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
	AJE40424.1	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
	AJE40559.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
	glyQS	glycyl-tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (460 aa)
	AJE40630.1	AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (623 aa)
	AJE40718.1	Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
	AJE40777.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
	AJE40798.1	Pyridoxal-dependent decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
	AJE40855.1	WD40 repeat, subgroup; Derived by automated computational analysis using gene prediction method: Protein Homology. (1187 aa)
	AJE40858.1	Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
	AJE41003.1	acyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
	AJE41024.1	Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
	AJE41047.1	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
	AJE41071.1	Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
	AJE41223.1	Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
	AJE41597.1	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
	AJE41654.1	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
	dnaK1	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (611 aa)
	AJE41736.1	Hypothetical protein; Required for the transposition of the insertion element. (105 aa)
	AJE41779.1	Aromatic acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
	AJE41908.1	Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (646 aa)
	AJE42224.1	Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
	AJE42290.1	Macrolide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
	AJE42373.1	Magnesium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
	lysA	Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (463 aa)
	AJE42549.1	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
	AJE43133.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (65 aa)
	AJE43154.1	Regulatory protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
	AJE43187.1	Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
	AJE43204.1	Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
	AJE43279.1	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
	AJE43281.1	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)

Your Current Organism:

Streptomyces nodosus

NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJE38904.1	AJE39085.1	SNOD_01635	SNOD_02810	Amino acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.419
AJE38904.1	AJE39699.1	SNOD_01635	SNOD_06480	Amino acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Carbon-nitrogen hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.419
AJE38904.1	AJE41024.1	SNOD_01635	SNOD_13940	Amino acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.884
AJE38904.1	AJE43204.1	SNOD_01635	SNOD_26635	Amino acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.419
AJE38904.1	AJE44214.1	SNOD_01635	SNOD_32665	Amino acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.496
AJE38904.1	lysA	SNOD_01635	SNOD_22670	Amino acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.	0.841
AJE39085.1	AJE38904.1	SNOD_02810	SNOD_01635	Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.419
AJE39085.1	AJE39378.1	SNOD_02810	SNOD_04525	Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.419
AJE39085.1	AJE41024.1	SNOD_02810	SNOD_13940	Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.419
AJE39085.1	AJE44214.1	SNOD_02810	SNOD_32665	Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.573
AJE39085.1	lysA	SNOD_02810	SNOD_22670	Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.	0.419
AJE39373.1	AJE44214.1	SNOD_04500	SNOD_32665	2,3-butanediol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.446
AJE39378.1	AJE39085.1	SNOD_04525	SNOD_02810	Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.419
AJE39378.1	AJE39699.1	SNOD_04525	SNOD_06480	Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Carbon-nitrogen hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.419
AJE39378.1	AJE41024.1	SNOD_04525	SNOD_13940	Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.844
AJE39378.1	AJE43204.1	SNOD_04525	SNOD_26635	Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.419
AJE39378.1	AJE44214.1	SNOD_04525	SNOD_32665	Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.419
AJE39378.1	lysA	SNOD_04525	SNOD_22670	Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.	0.811
AJE39406.1	dnaK	SNOD_04695	SNOD_03855	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.456
AJE39406.1	dnaK1	SNOD_04695	SNOD_17885	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.456

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