STRINGSTRING
purA purA AJE44073.1 AJE44073.1 glsA glsA aspA1 aspA1 AJE44024.1 AJE44024.1 AJE44007.1 AJE44007.1 AJE43964.1 AJE43964.1 AJE43771.1 AJE43771.1 AJE43491.1 AJE43491.1 AJE43278.1 AJE43278.1 AJE43205.1 AJE43205.1 AJE43172.1 AJE43172.1 AJE42778.1 AJE42778.1 AJE42660.1 AJE42660.1 AJE42256.1 AJE42256.1 glmS-2 glmS-2 AJE42004.1 AJE42004.1 AJE41978.1 AJE41978.1 AJE41937.1 AJE41937.1 AJE41795.1 AJE41795.1 AJE41638.1 AJE41638.1 AJE41617.1 AJE41617.1 purQ purQ purF purF AJE41344.1 AJE41344.1 AJE40958.1 AJE40958.1 glmS glmS AJE40408.1 AJE40408.1 AJE40384.1 AJE40384.1 AJE40230.1 AJE40230.1 gltD1 gltD1 gltD gltD AJE39987.1 AJE39987.1 AJE39841.1 AJE39841.1 argG argG argH argH pyrB pyrB AJE39725.1 AJE39725.1 carA carA carB carB AJE39560.1 AJE39560.1 AJE39512.1 AJE39512.1 AJE38753.1 AJE38753.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (427 aa)
AJE44073.1Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (613 aa)
glsAGlutaminase; Catalyzes the formation of glutamate from glutamine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaminase family. (313 aa)
aspA1Aspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
AJE44024.1Asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
AJE44007.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (430 aa)
AJE43964.1Sugar isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
AJE43771.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (467 aa)
AJE43491.1ATP-grasp domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
AJE43278.1Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
AJE43205.1Aminotransferase class III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (428 aa)
AJE43172.1Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
AJE42778.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
AJE42660.11-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (546 aa)
AJE42256.1Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
glmS-2Glutamine amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (615 aa)
AJE42004.1Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (451 aa)
AJE41978.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
AJE41937.1D-aspartate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
AJE41795.1Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the group II decarboxylase family. (470 aa)
AJE41638.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (639 aa)
AJE41617.1Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
purQPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (226 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (508 aa)
AJE41344.1Asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
AJE40958.1NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1646 aa)
glmSGlutamine amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (605 aa)
AJE40408.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (453 aa)
AJE40384.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
AJE40230.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1536 aa)
gltD1Glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)
AJE39987.1Alanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
AJE39841.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (456 aa)
argGArgininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (405 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
pyrBAspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (343 aa)
AJE39725.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (385 aa)
carBCarbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (1102 aa)
AJE39560.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (480 aa)
AJE39512.1Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
AJE38753.1Carbon-nitrogen hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
Your Current Organism:
Streptomyces nodosus
NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus
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