STRINGSTRING
AJE41494.1 AJE41494.1 pat pat AJE41978.1 AJE41978.1 AJE39286.1 AJE39286.1 aroB aroB aroK aroK aroC aroC AJE39738.1 AJE39738.1 AJE39843.1 AJE39843.1 AJE39979.1 AJE39979.1 AJE39980.1 AJE39980.1 aroQ aroQ AJE40225.1 AJE40225.1 trpA trpA trpB trpB trpC trpC trpE trpE priA-2 priA-2 hisC hisC AJE40313.1 AJE40313.1 AJE44244.1 AJE44244.1 trpF trpF AJE43278.1 AJE43278.1 aroA aroA AJE42213.1 AJE42213.1 AJE42085.1 AJE42085.1 trpD trpD AJE39111.1 AJE39111.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AJE41494.1Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
patAminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (359 aa)
AJE41978.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
AJE39286.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (363 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (171 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (394 aa)
AJE39738.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the shikimate dehydrogenase family. (282 aa)
AJE39843.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
AJE39979.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
AJE39980.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (157 aa)
AJE40225.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (116 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (271 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (428 aa)
trpCIndole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (269 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (496 aa)
priA-2Phosphoribosyl isomerase; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family. (243 aa)
hisCAspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (378 aa)
AJE40313.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (451 aa)
AJE44244.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
trpFPhosphoribosylanthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (199 aa)
AJE43278.1Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (438 aa)
AJE42213.1Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (206 aa)
AJE42085.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (354 aa)
AJE39111.1Prephenate dehydratase; Catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
Your Current Organism:
Streptomyces nodosus
NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.