STRINGSTRING
AJE44435.1 AJE44435.1 AJE41724.1 AJE41724.1 AJE41525.1 AJE41525.1 leuC leuC leuD leuD AJE42799.1 AJE42799.1 AJE42888.1 AJE42888.1 acnA acnA AJE43172.1 AJE43172.1 AJE43278.1 AJE43278.1 AJE43794.1 AJE43794.1 AJE44076.1 AJE44076.1 AJE44077.1 AJE44077.1 AJE44191.1 AJE44191.1 AJE44408.1 AJE44408.1 asd-2 asd-2 argB-2 argB-2 AJE44510.1 AJE44510.1 AJE41828.1 AJE41828.1 ilvD ilvD AJE41195.1 AJE41195.1 AJE41174.1 AJE41174.1 AJE40783.1 AJE40783.1 AJE40764.1 AJE40764.1 asd asd leuA leuA AJE40601.1 AJE40601.1 AJE40409.1 AJE40409.1 AJE40398.1 AJE40398.1 AJE40094.1 AJE40094.1 argC argC argJ argJ argB argB argD argD AJE39779.1 AJE39779.1 AJE39678.1 AJE39678.1 AJE39673.1 AJE39673.1 AJE39625.1 AJE39625.1 AJE39566.1 AJE39566.1 AJE39553.1 AJE39553.1 AJE39495.1 AJE39495.1 AJE38866.1 AJE38866.1 AJE38840.1 AJE38840.1 AJE38814.1 AJE38814.1 AJE38678.1 AJE38678.1 AJE41871.1 AJE41871.1 AJE41978.1 AJE41978.1 AJE42120.1 AJE42120.1 AJE42256.1 AJE42256.1 AJE42356.1 AJE42356.1 AJE42652.1 AJE42652.1 AJE42653.1 AJE42653.1 ilvC ilvC leuB leuB AJE42662.1 AJE42662.1 AJE42669.1 AJE42669.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AJE44435.1Amino acid acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
AJE41724.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (425 aa)
AJE41525.1GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (474 aa)
leuDIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa)
AJE42799.1GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
AJE42888.12,4-diaminobutyrate 4-aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (460 aa)
acnAAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (904 aa)
AJE43172.1Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
AJE43278.1Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
AJE43794.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)
AJE44076.1GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
AJE44077.1GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
AJE44191.1Sulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)
AJE44408.1Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
asd-2Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (355 aa)
argB-2Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (280 aa)
AJE44510.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
AJE41828.1N-acetylglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family. (179 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (617 aa)
AJE41195.1Citrate synthase 2; Forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (366 aa)
AJE41174.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (78 aa)
AJE40783.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (561 aa)
AJE40764.1Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (429 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (338 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (573 aa)
AJE40601.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
AJE40409.1Hemin transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the globin family. (394 aa)
AJE40398.1GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
AJE40094.1Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (423 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (342 aa)
argJN-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (385 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (294 aa)
argDAcetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (403 aa)
AJE39779.1Class IV aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
AJE39678.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
AJE39673.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa)
AJE39625.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
AJE39566.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
AJE39553.1GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
AJE39495.1Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (739 aa)
AJE38866.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the LeuD family. (140 aa)
AJE38840.1Thiamine pyrophosphate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (573 aa)
AJE38814.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (552 aa)
AJE38678.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
AJE41871.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
AJE41978.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
AJE42120.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
AJE42256.1Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
AJE42356.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
AJE42652.1Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (622 aa)
AJE42653.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (347 aa)
AJE42662.1Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
AJE42669.1Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (534 aa)
Your Current Organism:
Streptomyces nodosus
NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus
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