STRINGSTRING
secA secA AJE42735.1 AJE42735.1 AJE42733.1 AJE42733.1 ffh ffh ftsY ftsY AJE42680.1 AJE42680.1 AJE42676.1 AJE42676.1 AJE42497.1 AJE42497.1 AJE42467.1 AJE42467.1 tatB tatB secY secY secE secE tatA-2 tatA-2 AJE41554.1 AJE41554.1 AJE41483.1 AJE41483.1 AJE41208.1 AJE41208.1 AJE40657.1 AJE40657.1 AJE40656.1 AJE40656.1 AJE40514.1 AJE40514.1 lspA lspA AJE40164.1 AJE40164.1 AJE40027.1 AJE40027.1 AJE39916.1 AJE39916.1 tatA tatA AJE39860.1 AJE39860.1 AJE39755.1 AJE39755.1 secD secD secF secF AJE39659.1 AJE39659.1 AJE39114.1 AJE39114.1 AJE39016.1 AJE39016.1 AJE42736.1 AJE42736.1 tatA-3 tatA-3 AJE43089.1 AJE43089.1 AJE43428.1 AJE43428.1 AJE43713.1 AJE43713.1 AJE44060.1 AJE44060.1 AJE44118.1 AJE44118.1 AJE40956.1 AJE40956.1 AJE40955.1 AJE40955.1 AJE40950.1 AJE40950.1 AJE40947.1 AJE40947.1 AJE40946.1 AJE40946.1 AJE40945.1 AJE40945.1 AJE40850.1 AJE40850.1 AJE40787.1 AJE40787.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (937 aa)
AJE42735.1Signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (307 aa)
AJE42733.1Signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (239 aa)
ffhSignal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (515 aa)
ftsYCell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (400 aa)
AJE42680.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
AJE42676.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
AJE42497.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
AJE42467.1Signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
tatBPreprotein translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (143 aa)
secYPreprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (437 aa)
secEPreprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (95 aa)
tatA-2Hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (76 aa)
AJE41554.1Protein translocase component YidC; Functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
AJE41483.1Topoisomerase II; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
AJE41208.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
AJE40657.1Glycosyl transferase family A; Derived by automated computational analysis using gene prediction method: Protein Homology. (1187 aa)
AJE40656.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (743 aa)
AJE40514.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
lspAHypothetical protein; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (208 aa)
AJE40164.1Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (76 aa)
AJE40027.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
AJE39916.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0225 family. (126 aa)
tatAPreprotein translocase subunit TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (94 aa)
AJE39860.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
AJE39755.1Preprotein translocase, YajC subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
secDPreprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (587 aa)
secFPreprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (368 aa)
AJE39659.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
AJE39114.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
AJE39016.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (508 aa)
AJE42736.1Signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. (247 aa)
tatA-3Twin-arginine translocation protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (86 aa)
AJE43089.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
AJE43428.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
AJE43713.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
AJE44060.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
AJE44118.1CDP-glycerol:glycerophosphate glycerophosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (950 aa)
AJE40956.1Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (558 aa)
AJE40955.1Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (744 aa)
AJE40950.1Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (538 aa)
AJE40947.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (735 aa)
AJE40946.1Glycosyl transferase family A; Derived by automated computational analysis using gene prediction method: Protein Homology. (725 aa)
AJE40945.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (751 aa)
AJE40850.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
AJE40787.1Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
Your Current Organism:
Streptomyces nodosus
NCBI taxonomy Id: 40318
Other names: ATCC 14899, ATCC 23942, BCRC 13768, CBS 926.68, CCRC 13768, CCRC:13768, DSM 40109, IFO 12895, ISP 5109, JCM 4297, JCM 4656, KCTC 9035, LMG 19340, LMG:19340, NBRC 12895, NCIMB 12816, NRRL B-2371, NRRL-ISP 5109, RIA 831, S. nodosus
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