(28 nodes) 90S preribosome network (Batrachochytrium dendrobatidis JEL423)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BDEG_20156	Ribosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family. (301 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1173 aa)
	BDEG_20580	Uncharacterized protein; Belongs to the DEAD box helicase family. (553 aa)
	BDEG_20921	WD_REPEATS_REGION domain-containing protein. (899 aa)
	BDEG_21223	Uncharacterized protein. (279 aa)
	BDEG_23062	WD_REPEATS_REGION domain-containing protein. (877 aa)
	BDEG_23032	CBF domain-containing protein. (93 aa)
	BDEG_23031	CBF domain-containing protein. (376 aa)
	BDEG_23517	NUC153 domain-containing protein. (698 aa)
	BDEG_22851	U3 small nucleolar RNA-associated protein 22. (1256 aa)
	BDEG_23265	Uncharacterized protein. (351 aa)
	BDEG_23582	RNA helicase. (659 aa)
	BDEG_23361	WD_REPEATS_REGION domain-containing protein. (973 aa)
	BDEG_23493	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (317 aa)
	BDEG_23242	Uncharacterized protein. (775 aa)
	BDEG_24264	Uncharacterized protein. (527 aa)
	BDEG_24717	Uncharacterized protein. (903 aa)
	BDEG_25377	Brix domain-containing protein. (247 aa)
	BDEG_25435	WD_REPEATS_REGION domain-containing protein. (975 aa)
	BDEG_27013	S4 RNA-binding domain-containing protein. (182 aa)
	BDEG_26920	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (704 aa)
	BDEG_27513	Uncharacterized protein. (285 aa)
	BDEG_28205	WD_REPEATS_REGION domain-containing protein. (580 aa)
	BDEG_23374	CBF domain-containing protein. (1171 aa)
	BDEG_28648	RRM domain-containing protein. (358 aa)
	BDEG_20155	Uncharacterized protein. (671 aa)
	BDEG_20382	RNA helicase. (583 aa)
	BDEG_20236	18S rRNA biogenesis protein RCL1. (378 aa)

Your Current Organism:

Batrachochytrium dendrobatidis JEL423

NCBI taxonomy Id: 403673
Other names: B. dendrobatidis JEL423

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDEG_20155	BDEG_20156	A0A177W785	A0A177W8I5	Uncharacterized protein.	Ribosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family.	0.642
BDEG_20155	BDEG_20236	A0A177W785	A0A177W8C8	Uncharacterized protein.	18S rRNA biogenesis protein RCL1.	0.991
BDEG_20155	BDEG_20382	A0A177W785	A0A177W7Z7	Uncharacterized protein.	RNA helicase.	0.579
BDEG_20155	BDEG_20580	A0A177W785	A0A177W9L4	Uncharacterized protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.807
BDEG_20155	BDEG_20921	A0A177W785	A0A177WAI8	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.999
BDEG_20155	BDEG_21223	A0A177W785	A0A177WC34	Uncharacterized protein.	Uncharacterized protein.	0.976
BDEG_20155	BDEG_22851	A0A177W785	A0A177WHY2	Uncharacterized protein.	U3 small nucleolar RNA-associated protein 22.	0.998
BDEG_20155	BDEG_23031	A0A177W785	A0A177WHJ9	Uncharacterized protein.	CBF domain-containing protein.	0.910
BDEG_20155	BDEG_23032	A0A177W785	A0A177WHF6	Uncharacterized protein.	CBF domain-containing protein.	0.910
BDEG_20155	BDEG_23062	A0A177W785	A0A177WGE4	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.999
BDEG_20155	BDEG_23242	A0A177W785	A0A177WJ62	Uncharacterized protein.	Uncharacterized protein.	0.785
BDEG_20155	BDEG_23265	A0A177W785	A0A177WI07	Uncharacterized protein.	Uncharacterized protein.	0.990
BDEG_20155	BDEG_23361	A0A177W785	A0A177WI92	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.985
BDEG_20155	BDEG_23374	A0A177W785	A0A177WIJ8	Uncharacterized protein.	CBF domain-containing protein.	0.771
BDEG_20155	BDEG_23493	A0A177W785	A0A177WJ21	Uncharacterized protein.	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.	0.947
BDEG_20155	BDEG_23517	A0A177W785	A0A177WHU8	Uncharacterized protein.	NUC153 domain-containing protein.	0.990
BDEG_20155	BDEG_24264	A0A177W785	A0A177WLH3	Uncharacterized protein.	Uncharacterized protein.	0.991
BDEG_20155	BDEG_24717	A0A177W785	A0A177WMN9	Uncharacterized protein.	Uncharacterized protein.	0.992
BDEG_20155	BDEG_25377	A0A177W785	A0A177WNZ8	Uncharacterized protein.	Brix domain-containing protein.	0.989
BDEG_20155	BDEG_25435	A0A177W785	A0A177WQI2	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.999