(36 nodes) Formation of the Early Elongation Complex network (Batrachochytrium dendrobatidis JEL423)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	BDEG_23068	Nuclear cap-binding protein subunit 2. (221 aa)
	BDEG_22944	DNA-directed RNA polymerase I, II, and III subunit RPABC5. (98 aa)
	BDEG_23650	Cyclin domain-containing protein; Belongs to the cyclin family. (354 aa)
	BDEG_23504	Uncharacterized protein. (752 aa)
	BDEG_24031	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1743 aa)
	BDEG_24201	RPOL4c domain-containing protein. (138 aa)
	BDEG_24392	RNA polymerase Rpb3/Rpb11 dimerization domain-containing protein. (125 aa)
	BDEG_24664	Cyclin domain-containing protein. (305 aa)
	BDEG_24334	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (424 aa)
	BDEG_24658	Cyclin domain-containing protein. (306 aa)
	BDEG_24936	Uncharacterized protein. (78 aa)
	BDEG_25167	Uncharacterized protein. (851 aa)
	BDEG_25069	Helicase ATP-binding domain-containing protein. (688 aa)
	BDEG_25533	Uncharacterized protein. (480 aa)
	BDEG_25451	RNA polymerase Rpb5 domain-containing protein. (207 aa)
	BDEG_26209	Uncharacterized protein. (372 aa)
	BDEG_25760	Uncharacterized protein. (269 aa)
	BDEG_26064	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1710 aa)
	BDEG_26568	Uncharacterized protein. (299 aa)
	BDEG_26308	Uncharacterized protein. (556 aa)
	BDEG_26947	RNA polymerase Rpb3/RpoA insert domain-containing protein. (285 aa)
	BDEG_26953	FCP1 homology domain-containing protein. (873 aa)
	BDEG_26792	Uncharacterized protein. (826 aa)
	BDEG_27290	Protein kinase domain-containing protein. (370 aa)
	BDEG_27680	CDK-activating kinase assembly factor MAT1. (256 aa)
	BDEG_28179	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (414 aa)
	BDEG_28111	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (116 aa)
	BDEG_21970	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (139 aa)
	BDEG_21805	RNA polymerase Rpb6. (148 aa)
	BDEG_21829	Uncharacterized protein. (876 aa)
	BDEG_21549	Uncharacterized protein. (256 aa)
	BDEG_20903	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (786 aa)
	BDEG_20817	Uncharacterized protein. (823 aa)
	BDEG_20324	Uncharacterized protein. (112 aa)
	BDEG_20125	Uncharacterized protein. (180 aa)
	BDEG_20325	Uncharacterized protein. (870 aa)

Your Current Organism:

Batrachochytrium dendrobatidis JEL423

NCBI taxonomy Id: 403673
Other names: B. dendrobatidis JEL423

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDEG_20125	BDEG_20324	A0A177W817	A0A177W8M3	Uncharacterized protein.	Uncharacterized protein.	0.955
BDEG_20125	BDEG_20325	A0A177W817	A0A177W7P1	Uncharacterized protein.	Uncharacterized protein.	0.955
BDEG_20125	BDEG_20817	A0A177W817	A0A177W991	Uncharacterized protein.	Uncharacterized protein.	0.871
BDEG_20125	BDEG_20903	A0A177W817	A0A177W9J5	Uncharacterized protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.987
BDEG_20125	BDEG_21549	A0A177W817	A0A177WBT2	Uncharacterized protein.	Uncharacterized protein.	0.964
BDEG_20125	BDEG_21805	A0A177W817	A0A177WDS4	Uncharacterized protein.	RNA polymerase Rpb6.	0.999
BDEG_20125	BDEG_21829	A0A177W817	A0A177WDJ7	Uncharacterized protein.	Uncharacterized protein.	0.871
BDEG_20125	BDEG_21970	A0A177W817	A0A177WF53	Uncharacterized protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.999
BDEG_20125	BDEG_22944	A0A177W817	A0A177WHT8	Uncharacterized protein.	DNA-directed RNA polymerase I, II, and III subunit RPABC5.	0.999
BDEG_20125	BDEG_23068	A0A177W817	A0A177WHP3	Uncharacterized protein.	Nuclear cap-binding protein subunit 2.	0.649
BDEG_20125	BDEG_23504	A0A177W817	A0A177WJ31	Uncharacterized protein.	Uncharacterized protein.	0.968
BDEG_20125	BDEG_23650	A0A177W817	A0A177WIE3	Uncharacterized protein.	Cyclin domain-containing protein; Belongs to the cyclin family.	0.824
BDEG_20125	BDEG_24031	A0A177W817	A0A177WKD1	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.995
BDEG_20125	BDEG_24201	A0A177W817	A0A177WKX6	Uncharacterized protein.	RPOL4c domain-containing protein.	0.999
BDEG_20125	BDEG_24334	A0A177W817	A0A177WLQ6	Uncharacterized protein.	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	0.949
BDEG_20125	BDEG_24392	A0A177W817	A0A177WLK9	Uncharacterized protein.	RNA polymerase Rpb3/Rpb11 dimerization domain-containing protein.	0.999
BDEG_20125	BDEG_24658	A0A177W817	A0A177WMC7	Uncharacterized protein.	Cyclin domain-containing protein.	0.824
BDEG_20125	BDEG_24664	A0A177W817	A0A177WLL2	Uncharacterized protein.	Cyclin domain-containing protein.	0.824
BDEG_20125	BDEG_24936	A0A177W817	A0A177WNP7	Uncharacterized protein.	Uncharacterized protein.	0.999
BDEG_20125	BDEG_25069	A0A177W817	A0A177WP89	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.948