(31 nodes) Mixed, incl. Histidine metabolic process, and Aromatic amino acid family biosynthetic process network (Phytophthora infestans)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	PITG_00221	Tryptophan synthase, putative; Belongs to the TrpA family. (270 aa)
	PITG_01711	Anthranilate synthase component I, putative. (504 aa)
	PITG_01769	Chorismate synthase. (456 aa)
	PITG_01245	Chorismate mutase, putative. (558 aa)
	PITG_02182	Homoserine dehydrogenase. (437 aa)
	PITG_02198	Homoserine kinase, putative. (412 aa)
	PITG_02854	Aspartate-semialdehyde dehydrogenase, putative. (391 aa)
	PITG_03620	Histidinol-phosphate aminotransferase, putative. (418 aa)
	PITG_03009	Uncharacterized protein. (114 aa)
	PITG_03010	Helicase ATP-binding domain-containing protein. (774 aa)
	PITG_03014	F-box protein, putative. (1126 aa)
	PITG_05245	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (582 aa)
	PITG_05318	N-(5'-phosphoribosyl)anthranilate isomerase indole-3-glycerol-phosphate synthase, putative. (561 aa)
	PITG_05805	Tryptophan synthase. (424 aa)
	PITG_07098	Para-aminobenzoate synthase, putative. (795 aa)
	PITG_09582	ATP phosphoribosyltransferase. (299 aa)
	PITG_09698	Histidine biosynthesis trifunctional protein, putative. (477 aa)
	PITG_09783	Aminotran_1_2 domain-containing protein. (367 aa)
	PITG_09815	Anthranilate synthase component 2, putative. (236 aa)
	PITG_10777	Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (426 aa)
	PITG_13139	Threonine synthase. (497 aa)
	PITG_13176	Diaminopimelate decarboxylase, putative; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (410 aa)
	PITG_12514	Bifunctional aspartokinase/homoserine dehydrogenase, putative. (893 aa)
	PITG_13429	Aspartokinase, putative. (596 aa)
	PITG_13924	Bifunctional aspartokinase/homoserine dehydrogenase, putative. (911 aa)
	PITG_15294	Histidinol dehydrogenase, putative; Belongs to the histidinol dehydrogenase family. (456 aa)
	PITG_14634	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Belongs to the HisA/HisF family. (260 aa)
	PITG_17032	Anthranilate phosphoribosyltransferase, putative. (354 aa)
	PITG_18063	Bifunctional polynucleotide phosphatase/kinase, putative. (430 aa)
	PITG_18962	DNA repair protein, putative. (736 aa)
	PITG_20965	Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (446 aa)

Your Current Organism:

Phytophthora infestans

NCBI taxonomy Id: 403677
Other names: P. infestans T30-4, Phytophthora infestans T30-4, Phytophthora infestans strain T30-4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PITG_00221	PITG_01245	D0MQ90	D0MV05	Tryptophan synthase, putative; Belongs to the TrpA family.	Chorismate mutase, putative.	0.655
PITG_00221	PITG_01711	D0MQ90	D0MTW7	Tryptophan synthase, putative; Belongs to the TrpA family.	Anthranilate synthase component I, putative.	0.991
PITG_00221	PITG_01769	D0MQ90	D0MU16	Tryptophan synthase, putative; Belongs to the TrpA family.	Chorismate synthase.	0.975
PITG_00221	PITG_02182	D0MQ90	D0MVP3	Tryptophan synthase, putative; Belongs to the TrpA family.	Homoserine dehydrogenase.	0.529
PITG_00221	PITG_02198	D0MQ90	D0MVQ7	Tryptophan synthase, putative; Belongs to the TrpA family.	Homoserine kinase, putative.	0.670
PITG_00221	PITG_02854	D0MQ90	D0MXD8	Tryptophan synthase, putative; Belongs to the TrpA family.	Aspartate-semialdehyde dehydrogenase, putative.	0.777
PITG_00221	PITG_03009	D0MQ90	D0MZ53	Tryptophan synthase, putative; Belongs to the TrpA family.	Uncharacterized protein.	0.770
PITG_00221	PITG_03010	D0MQ90	D0MZ54	Tryptophan synthase, putative; Belongs to the TrpA family.	Helicase ATP-binding domain-containing protein.	0.770
PITG_00221	PITG_03014	D0MQ90	D0MZ57	Tryptophan synthase, putative; Belongs to the TrpA family.	F-box protein, putative.	0.770
PITG_00221	PITG_03620	D0MQ90	D0MY30	Tryptophan synthase, putative; Belongs to the TrpA family.	Histidinol-phosphate aminotransferase, putative.	0.953
PITG_00221	PITG_05245	D0MQ90	D0N3W2	Tryptophan synthase, putative; Belongs to the TrpA family.	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	0.749
PITG_00221	PITG_05318	D0MQ90	D0N427	Tryptophan synthase, putative; Belongs to the TrpA family.	N-(5'-phosphoribosyl)anthranilate isomerase indole-3-glycerol-phosphate synthase, putative.	0.998
PITG_00221	PITG_05805	D0MQ90	D0N5Q5	Tryptophan synthase, putative; Belongs to the TrpA family.	Tryptophan synthase.	0.999
PITG_00221	PITG_07098	D0MQ90	D0N795	Tryptophan synthase, putative; Belongs to the TrpA family.	Para-aminobenzoate synthase, putative.	0.988
PITG_00221	PITG_09582	D0MQ90	D0NCB8	Tryptophan synthase, putative; Belongs to the TrpA family.	ATP phosphoribosyltransferase.	0.686
PITG_00221	PITG_09698	D0MQ90	D0NCL3	Tryptophan synthase, putative; Belongs to the TrpA family.	Histidine biosynthesis trifunctional protein, putative.	0.986
PITG_00221	PITG_09783	D0MQ90	D0NCT6	Tryptophan synthase, putative; Belongs to the TrpA family.	Aminotran_1_2 domain-containing protein.	0.953
PITG_00221	PITG_09815	D0MQ90	D0NEM4	Tryptophan synthase, putative; Belongs to the TrpA family.	Anthranilate synthase component 2, putative.	0.998
PITG_00221	PITG_10777	D0MQ90	D0NH24	Tryptophan synthase, putative; Belongs to the TrpA family.	Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family.	0.637
PITG_00221	PITG_12514	D0MQ90	D0NKQ0	Tryptophan synthase, putative; Belongs to the TrpA family.	Bifunctional aspartokinase/homoserine dehydrogenase, putative.	0.529