(28 nodes) Pyrimidine metabolism, and Deoxyribonucleotide biosynthetic process network (Phytophthora infestans)

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Your Input:
	PITG_00765	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (198 aa)
	PITG_00985	Serine hydrolase (FSH1), putative. (186 aa)
	PITG_01742	Thymidine kinase. (174 aa)
	PITG_01263	Folate-Biopterin Transporter (FBT) family. (561 aa)
	PITG_02105	Uracil phosphoribosyltransferase, putative. (227 aa)
	PITG_02221	Thymidylate kinase. (216 aa)
	PITG_02692	Uncharacterized protein. (486 aa)
	PITG_03143	Indigoidine synthase A family protein, putative. (707 aa)
	PITG_03347	Ribonucleoside-diphosphate reductase small chain. (379 aa)
	PITG_05998	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (793 aa)
	PITG_06977	Deoxycytidylate deaminase. (252 aa)
	PITG_07080	Uncharacterized protein. (279 aa)
	PITG_07316	Uncharacterized protein. (216 aa)
	PITG_06749	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. (509 aa)
	PITG_09597	Uncharacterized protein. (375 aa)
	PITG_09635	Orotidine 5'-phosphate decarboxylase, putative. (477 aa)
	PITG_09906	Arabinogalactan endo-beta-1,4-galactanase. (324 aa)
	PITG_10615	CEP44 domain-containing protein. (234 aa)
	PITG_12121	Uridine kinase; Belongs to the uridine kinase family. (307 aa)
	PITG_12840	HTH psq-type domain-containing protein. (542 aa)
	PITG_12841	HTH psq-type domain-containing protein. (476 aa)
	PITG_15494	Cytosine deaminase. (145 aa)
	PITG_15659	Ribonucleoside-diphosphate reductase small chain. (360 aa)
	PITG_16336	tRNA-specific adenosine deaminase, putative. (130 aa)
	PITG_17289	Deoxyuridine 5'-triphosphate nucleotidohydrolase. (239 aa)
	PITG_17295	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (174 aa)
	PITG_20148	Uncharacterized protein. (544 aa)
	PITG_20614	Deoxycytidylate deaminase. (122 aa)

Your Current Organism:

Phytophthora infestans

NCBI taxonomy Id: 403677
Other names: P. infestans T30-4, Phytophthora infestans T30-4, Phytophthora infestans strain T30-4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PITG_00765	PITG_02105	D0MRN1	D0MVH7	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uracil phosphoribosyltransferase, putative.	0.939
PITG_00765	PITG_02221	D0MRN1	D0MVS5	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Thymidylate kinase.	0.709
PITG_00765	PITG_02692	D0MRN1	D0MWZ7	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uncharacterized protein.	0.939
PITG_00765	PITG_05998	D0MRN1	D0N666	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.639
PITG_00765	PITG_06749	D0MRN1	D0N806	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	0.633
PITG_00765	PITG_06977	D0MRN1	D0N6Y3	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Deoxycytidylate deaminase.	0.901
PITG_00765	PITG_07080	D0MRN1	D0N778	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uncharacterized protein.	0.939
PITG_00765	PITG_09597	D0MRN1	D0NCD1	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uncharacterized protein.	0.520
PITG_00765	PITG_09635	D0MRN1	D0NCG2	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Orotidine 5'-phosphate decarboxylase, putative.	0.958
PITG_00765	PITG_12121	D0MRN1	D0NJ34	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uridine kinase; Belongs to the uridine kinase family.	0.420
PITG_00765	PITG_12840	D0MRN1	D0NLA3	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	HTH psq-type domain-containing protein.	0.939
PITG_00765	PITG_12841	D0MRN1	D0NLA4	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	HTH psq-type domain-containing protein.	0.939
PITG_00765	PITG_17289	D0MRN1	D0NVQ2	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Deoxyuridine 5'-triphosphate nucleotidohydrolase.	0.589
PITG_00765	PITG_20614	D0MRN1	D0P2D5	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Deoxycytidylate deaminase.	0.901
PITG_00985	PITG_01742	D0MS61	D0MTZ4	Serine hydrolase (FSH1), putative.	Thymidine kinase.	0.786
PITG_00985	PITG_02221	D0MS61	D0MVS5	Serine hydrolase (FSH1), putative.	Thymidylate kinase.	0.816
PITG_00985	PITG_05998	D0MS61	D0N666	Serine hydrolase (FSH1), putative.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.469
PITG_00985	PITG_06749	D0MS61	D0N806	Serine hydrolase (FSH1), putative.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	0.976
PITG_00985	PITG_06977	D0MS61	D0N6Y3	Serine hydrolase (FSH1), putative.	Deoxycytidylate deaminase.	0.429
PITG_00985	PITG_10615	D0MS61	D0NFQ3	Serine hydrolase (FSH1), putative.	CEP44 domain-containing protein.	0.429