(28 nodes) Pyrimidine metabolism network (Phytophthora infestans)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	PITG_00765	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (198 aa)
	PITG_01742	Thymidine kinase. (174 aa)
	PITG_01913	Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (424 aa)
	PITG_02105	Uracil phosphoribosyltransferase, putative. (227 aa)
	PITG_02221	Thymidylate kinase. (216 aa)
	PITG_02621	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (602 aa)
	PITG_02692	Uncharacterized protein. (486 aa)
	PITG_03634	Nucleoside diphosphate kinase, putative. (339 aa)
	PITG_03143	Indigoidine synthase A family protein, putative. (707 aa)
	PITG_03296	AAA domain-containing protein. (2023 aa)
	PITG_06352	Uncharacterized protein. (455 aa)
	PITG_06977	Deoxycytidylate deaminase. (252 aa)
	PITG_07080	Uncharacterized protein. (279 aa)
	PITG_06749	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. (509 aa)
	PITG_07904	Pyrimidine 5'-nucleotidase (UMPH-1)-like protein. (363 aa)
	PITG_07911	Cytosolic 5'-nucleotidase III-like protein. (361 aa)
	PITG_09576	Orotidine 5'-phosphate decarboxylase, putative. (480 aa)
	PITG_09596	Nucleoside diphosphate kinase. (151 aa)
	PITG_09635	Orotidine 5'-phosphate decarboxylase, putative. (477 aa)
	PITG_08761	Nucleoside diphosphate kinase. (221 aa)
	PITG_12840	HTH psq-type domain-containing protein. (542 aa)
	PITG_12841	HTH psq-type domain-containing protein. (476 aa)
	PITG_15494	Cytosine deaminase. (145 aa)
	PITG_16203	Purine nucleoside phosphorylase 1. (363 aa)
	PITG_17289	Deoxyuridine 5'-triphosphate nucleotidohydrolase. (239 aa)
	PITG_17711	Purine nucleoside phosphorylase 1. (351 aa)
	PITG_20614	Deoxycytidylate deaminase. (122 aa)
	PITG_20792	Soluble calcium-activated nucleotidase, putative. (455 aa)

Your Current Organism:

Phytophthora infestans

NCBI taxonomy Id: 403677
Other names: P. infestans T30-4, Phytophthora infestans T30-4, Phytophthora infestans strain T30-4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PITG_00765	PITG_02105	D0MRN1	D0MVH7	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uracil phosphoribosyltransferase, putative.	0.939
PITG_00765	PITG_02221	D0MRN1	D0MVS5	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Thymidylate kinase.	0.709
PITG_00765	PITG_02621	D0MRN1	D0MWT2	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.567
PITG_00765	PITG_02692	D0MRN1	D0MWZ7	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uncharacterized protein.	0.939
PITG_00765	PITG_03296	D0MRN1	D0MZV9	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	AAA domain-containing protein.	0.926
PITG_00765	PITG_03634	D0MRN1	D0MY44	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Nucleoside diphosphate kinase, putative.	0.950
PITG_00765	PITG_06352	D0MRN1	D0N4N1	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uncharacterized protein.	0.906
PITG_00765	PITG_06749	D0MRN1	D0N806	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	0.633
PITG_00765	PITG_06977	D0MRN1	D0N6Y3	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Deoxycytidylate deaminase.	0.901
PITG_00765	PITG_07080	D0MRN1	D0N778	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uncharacterized protein.	0.939
PITG_00765	PITG_07904	D0MRN1	D0NA41	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Pyrimidine 5'-nucleotidase (UMPH-1)-like protein.	0.900
PITG_00765	PITG_07911	D0MRN1	D0NA46	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Cytosolic 5'-nucleotidase III-like protein.	0.900
PITG_00765	PITG_08761	D0MRN1	D0ND55	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Nucleoside diphosphate kinase.	0.950
PITG_00765	PITG_09576	D0MRN1	D0NCB2	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Orotidine 5'-phosphate decarboxylase, putative.	0.958
PITG_00765	PITG_09596	D0MRN1	D0NCD0	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Nucleoside diphosphate kinase.	0.950
PITG_00765	PITG_09635	D0MRN1	D0NCG2	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Orotidine 5'-phosphate decarboxylase, putative.	0.958
PITG_00765	PITG_12840	D0MRN1	D0NLA3	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	HTH psq-type domain-containing protein.	0.939
PITG_00765	PITG_12841	D0MRN1	D0NLA4	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	HTH psq-type domain-containing protein.	0.939
PITG_00765	PITG_16203	D0MRN1	D0NTD2	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Purine nucleoside phosphorylase 1.	0.411
PITG_00765	PITG_17289	D0MRN1	D0NVQ2	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Deoxyuridine 5'-triphosphate nucleotidohydrolase.	0.589