(25 nodes) Pyruvate metabolism, and Pyruvate-flavodoxin oxidoreductase, central domain network (Geobacter bemidjiensis)

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Your Input:
	por-1	Pyruvate:ferredoxin/flavodoxin oxidoreductase. (1183 aa)
	Gbem_0226	Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (911 aa)
	pyc	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1148 aa)
	ppdK	Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (914 aa)
	pckA-2	Phosphoenolpyruvate carboxykinase, ATP-dependent; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (537 aa)
	pckA	Phosphoenolpyruvate carboxykinase, GTP-dependent; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (647 aa)
	fumB	Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (541 aa)
	pyk	Pyruvate kinase; Belongs to the pyruvate kinase family. (481 aa)
	maeB-1	Malate oxidoreductase, NADP-dependent, phosphate acetyltransferase-like domain-containing. (749 aa)
	oadA	Oxaloacetate decarboxylase. (690 aa)
	maeB-2	Malate oxidoreductase, NADP-dependent, phosphate acetyltransferase-like domain-containing. (779 aa)
	maeB-3	Malate oxidoreductase, NADP-dependent, phosphate acetyltransferase-like domain-containing. (749 aa)
	aspA	Aspartate ammonia-lyase. (466 aa)
	korC	2-oxoglutarate:ferredoxin oxidoreductase, gamma subunit. (182 aa)
	korB	2-oxoglutarate:ferredoxin oxidoreductase, thiamin diphosphate-binding subunit. (270 aa)
	korA	2-oxoglutarate:ferredoxin oxidoreductase, alpha subunit. (377 aa)
	korD	2-oxoglutarate:ferredoxin oxidoreductase, ferredoxin subunit. (64 aa)
	mdh	Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (317 aa)
	icd	Isocitrate dehydrogenase, NADP-dependent; Belongs to the monomeric-type IDH family. (743 aa)
	vorC	2-oxoacid:ferredoxin oxidoreductase, gamma subunit. (183 aa)
	vorB	2-oxoacid:ferredoxin oxidoreductase, thiamin diphosphate-binding subunit. (246 aa)
	vorA	2-oxoacid:ferredoxin oxidoreductase, alpha subunit. (368 aa)
	vorD	2-oxoacid:ferredoxin oxidoreductase, ferredoxin subunit. (67 aa)
	Gbem_3555	Cyclase/hydrolase, putative. (226 aa)
	por-2	Pyruvate:ferredoxin/flavodoxin oxidoreductase. (1238 aa)

Your Current Organism:

Geobacter bemidjiensis

NCBI taxonomy Id: 404380
Other names: G. bemidjiensis Bem, Geobacter bemidjiensis Bem, Geobacter bemidjiensis str. Bem, Geobacter bemidjiensis strain Bem

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Gbem_0226	Gbem_3555	Gbem_0226	Gbem_3555	Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.	Cyclase/hydrolase, putative.	0.800
Gbem_0226	mdh	Gbem_0226	Gbem_2900	Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.	Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.	0.926
Gbem_0226	oadA	Gbem_0226	Gbem_1454	Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.	Oxaloacetate decarboxylase.	0.936
Gbem_0226	pckA	Gbem_0226	Gbem_0734	Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.	Phosphoenolpyruvate carboxykinase, GTP-dependent; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.	0.935
Gbem_0226	pckA-2	Gbem_0226	Gbem_0733	Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.	Phosphoenolpyruvate carboxykinase, ATP-dependent; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.	0.926
Gbem_0226	ppdK	Gbem_0226	Gbem_0644	Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.	Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.	0.918
Gbem_0226	pyc	Gbem_0226	Gbem_0273	Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.926
Gbem_0226	pyk	Gbem_0226	Gbem_1182	Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.926
Gbem_3555	Gbem_0226	Gbem_3555	Gbem_0226	Cyclase/hydrolase, putative.	Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.	0.800
Gbem_3555	fumB	Gbem_3555	Gbem_0889	Cyclase/hydrolase, putative.	Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	0.808
Gbem_3555	maeB-1	Gbem_3555	Gbem_1324	Cyclase/hydrolase, putative.	Malate oxidoreductase, NADP-dependent, phosphate acetyltransferase-like domain-containing.	0.800
Gbem_3555	maeB-2	Gbem_3555	Gbem_1455	Cyclase/hydrolase, putative.	Malate oxidoreductase, NADP-dependent, phosphate acetyltransferase-like domain-containing.	0.800
Gbem_3555	maeB-3	Gbem_3555	Gbem_1888	Cyclase/hydrolase, putative.	Malate oxidoreductase, NADP-dependent, phosphate acetyltransferase-like domain-containing.	0.800
Gbem_3555	mdh	Gbem_3555	Gbem_2900	Cyclase/hydrolase, putative.	Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.	0.800
Gbem_3555	oadA	Gbem_3555	Gbem_1454	Cyclase/hydrolase, putative.	Oxaloacetate decarboxylase.	0.806
Gbem_3555	pckA	Gbem_3555	Gbem_0734	Cyclase/hydrolase, putative.	Phosphoenolpyruvate carboxykinase, GTP-dependent; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.	0.800
Gbem_3555	pckA-2	Gbem_3555	Gbem_0733	Cyclase/hydrolase, putative.	Phosphoenolpyruvate carboxykinase, ATP-dependent; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.	0.800
Gbem_3555	pyc	Gbem_3555	Gbem_0273	Cyclase/hydrolase, putative.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.808
aspA	fumB	Gbem_2795	Gbem_0889	Aspartate ammonia-lyase.	Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	0.503
aspA	icd	Gbem_2795	Gbem_2901	Aspartate ammonia-lyase.	Isocitrate dehydrogenase, NADP-dependent; Belongs to the monomeric-type IDH family.	0.801