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| | pfk-1 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (359 aa) |
| | Gbem_3231 | Sensor histidine kinase response regulator, PAS domain-containing; Domains: PAS, HisKA, HATPase_c, REC. (914 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (202 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (225 aa) |
| | buk | Butyrate kinase; Belongs to the acetokinase family. (357 aa) |
| | Gbem_3143 | Sensor histidine kinase, PAS domain-containing; Domains: PAS, HATPase_c. (614 aa) |
| | Gbem_2962 | Sensor histidine kinase response regulator, CHASE and PAS domain-containing; Domains: CHASE, PAS, HisKA, HATPase_c, REC. (869 aa) |
| | phoR-2 | Phosphate sensor histidine kinase, HAMP and PAS domain-containing; Domains: HAMP, PAS, HisKA, HATPase_c. (584 aa) |
| | Gbem_2950 | Sensor histidine kinase response regulator, PAS domain-containing; Domains: PAS, HisKA, HATPase_c, REC. (1004 aa) |
| | Gbem_2947 | Sensor histidine kinase response regulator; Domains: HisKA, HATPase_c, REC. (642 aa) |
| | cheA34H-2 | Sensor histidine kinase CheA associated with MCPs of class 34H. (697 aa) |
| | Gbem_2865 | Sensor histidine kinase response regulator, PAS and PAS domain-containing; Domains: PAS, PAS, HisKA, HATPase_c, REC. (853 aa) |
| | Gbem_2864 | FIST domain protein. (396 aa) |
| | Gbem_2852 | Diacylglycerol kinase-related protein. (321 aa) |
| | pfk-3 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (390 aa) |
| | gnfL | Nitrogen fixation master sensor histidine kinase, PAS domain-containing; Domains: PAS, HisKA, HATPase_c. (361 aa) |
| | Gbem_2791 | Hypothetical protein. (416 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (280 aa) |
| | prsA | Ribose-5-phosphate 1-pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa) |
| | Gbem_2716 | Sensor histidine kinase, HAMP domain-containing; Domains: HAMP, HisKA, HATPase_c. (592 aa) |
| | Gbem_2690 | Protein kinase, ArgK family, putative. (314 aa) |
| | Gbem_2675 | Hypothetical protein. (242 aa) |
| | Gbem_2673 | Sensor histidine kinase, HAMP domain-containing; Domains: HAMP, HisKA, HATPase_c. (452 aa) |
| | Gbem_2657 | Sensor histidine kinase, Cache_1 and HAMP domain-containing; Domains: Cache_1, HAMP, HisKA, HATPase_c. (829 aa) |
| | Gbem_2646 | Kinase, putative. (518 aa) |
| | Gbem_2625 | Molybdenum storage protein. (268 aa) |
| | kdpD | Osmosensitive potassium channel sensor histidine kinase KdpD, KdpD and USP_OKCHK domain-containing; Domains: KdpD, USP_OKCHK, HisKA, HATPase_c. (892 aa) |
| | ribF | Riboflavin kinase and FAD synthetase; Belongs to the ribF family. (323 aa) |
| | pilS | Sensor histidine kinase PilS, PAS domain-containing; Domains: PAS, HisKA, HATPase_c. (539 aa) |
| | Gbem_2537 | Sensor histidine kinase, PAS and PAS domain-containing; Domains: PAS, PAS, HisKA, HATPase_c. (675 aa) |
| | ptsP | GAF domain phosphoenolpyruvate--protein phosphotransferase PtsP; Belongs to the PEP-utilizing enzyme family. (780 aa) |
| | Gbem_2483 | Carbohydrate kinase, PfkB family. (302 aa) |
| | pfk-2 | 6-phosphofructokinase, ATP-dependent; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa) |
| | ppnK | polyphosphate/ATP-dependent NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (288 aa) |
| | Gbem_2416 | Sensor histidine kinase response regulator; Domains: HisKA, HATPase_c, REC. (522 aa) |
| | Gbem_2406 | Response receiver sensor histidine kinase response regulator, PAS and PAS domain-containing; Domains: REC, PAS, PAS, HisKA, HATPase_c, REC. (773 aa) |
| | Gbem_2386 | Sensor histidine kinase; Domains: HATPase_c. (550 aa) |
| | cheAY40H-1 | Sensor histidine kinase CheA and response receiver CheY associated with MCPs of class 40H. (679 aa) |
| | cysN-1 | Sulfate adenylyltransferase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (551 aa) |
| | tpi | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa) |
| | coaX | Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (254 aa) |
| | Gbem_2312 | Cytidylate kinase-like domain phospholipid-binding protein, putative. (271 aa) |
| | ackA-1 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (421 aa) |
| | Gbem_2270 | Sensor histidine kinase, HAMP domain-containing; Domains: HAMP, HisKA, HATPase_c. (661 aa) |
| | Gbem_2254 | Sensor histidine kinase; Domains: HisKA_3, HATPase_c. (408 aa) |
| | Gbem_2240 | Sensor histidine kinase, HAMP domain-containing; Domains: HAMP, HisKA, HATPase_c. (672 aa) |
| | Gbem_2161 | Sensor histidine kinase; Domains: HisKA, HATPase_c. (412 aa) |
| | Gbem_2129 | Sensor histidine kinase; Domains: HisKA, HATPase_c. (282 aa) |
| | Gbem_2117 | Hypothetical protein. (687 aa) |
| | Gbem_2069 | Histidine kinase; Domains: DUF3365, PAS, PAS, GAF, PAS, HisKA, HATPase_c, REC. (1184 aa) |
| | Gbem_2047 | Hypothetical protein. (694 aa) |
| | cheAY40H-2 | Sensor histidine kinase CheA and response receiver CheY associated with MCPs of class 40H. (793 aa) |
| | glk | Glucose 6-kinase; Belongs to the bacterial glucokinase family. (327 aa) |
| | Gbem_1879 | Phosphoglycerate mutase family protein. (399 aa) |
| | phoR-1 | Phosphate sensor histidine kinase, HAMP and PAS domain-containing; Domains: HAMP, PAS, HisKA, HATPase_c. (460 aa) |
| | Gbem_1806 | Sensor histidine kinase, GAF domain-containing; Domains: GAF, HisKA, HATPase_c. (690 aa) |
| | Gbem_1701 | Sensor histidine kinase response regulator, PAS domain-containing; Domains: PAS, HisKA, HATPase_c, REC. (571 aa) |
| | Gbem_1662 | Response receiver histidine kinase; Domains: REC, HisKA, HATPase_c. (396 aa) |
| | Gbem_1657 | Adenosine kinase. (305 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (137 aa) |
| | cysN-2 | Sulfate adenylyltransferase, subunit 1. (408 aa) |
| | cheA34H-1 | Sensor histidine kinase CheA associated with MCPs of class 34H. (696 aa) |
| | aroK-1 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (170 aa) |
| | Gbem_1533 | Sensor histidine kinase, HAMP domain-containing; Domains: HAMP, HisKA, HATPase_c. (488 aa) |
| | Gbem_1505 | Sensor histidine kinase response regulator, HAMP and Hpt domain-containing; Domains: HAMP, HisKA, HATPase_c, REC, Hpt. (818 aa) |
| | Gbem_1486 | Sensor histidine kinase response regulator, HAMP domain-containing; Domains: HAMP, HisKA, HATPase_c, REC. (886 aa) |
| | bamV | Sensor histidine kinase; Domains: HisKA, HATPase_c. (603 aa) |
| | tal-2 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (374 aa) |
| | Gbem_1343 | Sensor histidine kinase; Domains: HisKA, HATPase_c. (330 aa) |
| | Gbem_1326 | ROK domain transcriptional regulator/sugar kinase. (306 aa) |
| | Gbem_1264 | Aspartate 4-kinase; Belongs to the aspartokinase family. (404 aa) |
| | yjeE | Nucleoid maintenance ATPase YjeE. (153 aa) |
| | pyk | Pyruvate kinase; Belongs to the pyruvate kinase family. (481 aa) |
| | Gbem_1171 | Sensor histidine kinase; Domains: HisKA, HATPase_c. (356 aa) |
| | Gbem_1094 | Sensor histidine kinase; Domains: HisKA, HATPase_c. (364 aa) |
| | cheA36H | Sensor histidine kinase CheA associated with MCPs of class 36H. (684 aa) |
| | ppk | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (822 aa) |
| | Gbem_1007 | Ketose-1,6-bisphosphate aldolase, class II, putative. (427 aa) |
| | Gbem_0999 | Diacylglycerol kinase-like protein. (235 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) |
| | Gbem_0902 | Quinone biosynthesis kinase AarF, putative. (560 aa) |
| | Gbem_0900 | Sensor histidine kinase, HAMP and PAS domain-containing; Domains: HAMP, PAS, HisKA, HATPase_c. (756 aa) |
| | ptsI | Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (586 aa) |
| | Gbem_0873 | Phosphotransferase system, mannose-type, protein IIA. (131 aa) |
| | hprK | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (316 aa) |
| | hldE | D-beta-D-heptose 1-phosphate adenylyltransferase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. (487 aa) |
| | lpxK | Tetraacyldisaccharide-1-phosphate 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (359 aa) |
| | Gbem_0772 | Hypothetical protein. (151 aa) |
| | cheA40H | Sensor histidine kinase CheA associated with MCPs of class 40H. (686 aa) |
| | Gbem_0709 | Sphingosine/diacylglycerol kinase-related protein. (289 aa) |
| | Gbem_0672 | Sensor histidine kinase response regulator, GAF and PAS domain-containing; Domains: GAF, PAS, HisKA, HATPase_c, REC. (770 aa) |
| | cbcK | Menaquinol oxidoreductase complex Cbc7; Cytochrome c subunit, putative, HAMP domain-containing, 2 heme-binding sites. (280 aa) |
| | coaE | Dephospho-coenzyme A kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (206 aa) |
| | Gbem_0655 | Sensor histidine kinase; Domains: HAMP, HisKA, HATPase_c; HAMP domain-containing, 2 heme-binding sites. (542 aa) |
| | ppdK | Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (914 aa) |
| | cheA44H | Sensor histidine kinase CheA associated with MCPs of class 44H. (543 aa) |
| | folK | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (162 aa) |
| | thiL | Thiamin monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (324 aa) |
| | Gbem_0535 | Sensor histidine kinase, PAS domain-containing; Domains: PAS, HisKA, HATPase_c. (554 aa) |
| | Gbem_0438 | Protein kinase, ABC1 domain-containing, putative; Domains: ABC1. (473 aa) |
| | Gbem_0377 | Cytidylate kinase-like domain protein. (234 aa) |
| | mak | D-fructose 6-kinase. (304 aa) |
| | ackA-2 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (409 aa) |
| | Gbem_0300 | Sensor protein, DUF3365 and HAMP domain-containing, heme-binding; Domains: DUF3365, HAMP. (405 aa) |
| | Gbem_0282 | Sensor histidine kinase, HAMP domain-containing, putative heme-binding site; Domains: HAMP, HisKA, HATPase_c. (494 aa) |
| | Gbem_0242 | Putative pyruvate, phosphate dikinase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (270 aa) |
| | rdoA | Protein serine/threonine kinase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (328 aa) |
| | Gbem_0201 | Nucleotide cyclase, HAMP and GGDEF-related domain-containing; Domains: HAMP, GGDEF-related. (446 aa) |
| | aroK-2 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (174 aa) |
| | citG-2 | 2'-(5''-triphosphoribosyl)-3'-dephospho-coenzyme A synthase. (267 aa) |
| | Gbem_0152 | Protein of unknown function YgbA. (100 aa) |
| | Gbem_0126 | Polyphosphate-dependent ADP kinase. (290 aa) |
| | Gbem_0065 | Response receiver histidine kinase response regulator; Domains: REC, HisKA, HATPase_c, REC. (578 aa) |
| | Gbem_0018 | Sensor histidine kinase; Domains: HisKA, HATPase_c. (289 aa) |
| | fgrL | Domains: REC, PAS, GAF, HisKA, HATPase_c. (715 aa) |
| | Gbem_4041 | Sensor histidine kinase, PAS domain-containing; Domains: PAS, HATPase_c. (619 aa) |
| | Gbem_4040 | FIST domain protein. (396 aa) |
| | galK | Galactose 1-kinase; Belongs to the GHMP kinase family. GalK subfamily. (357 aa) |
| | Gbem_3987 | Hypothetical protein. (221 aa) |
| | Gbem_3959 | Sensor protein, DUF3365, HAMP and PAS domain-containing, heme-binding; Domains: DUF3365, HAMP, PAS. (399 aa) |
| | cheA64H | Sensor histidine kinase CheA associated with MCPs of classes 40H and 40+24H. (603 aa) |
| | citG-1 | 2'-(5''-triphosphoribosyl)-3'-dephospho-coenzyme A synthase. (272 aa) |
| | Gbem_3846 | Sensor histidine kinase, PAS domain-containing; Domains: PAS, HisKA, HATPase_c. (352 aa) |
| | Gbem_3818 | Sensor histidine kinase, HAMP domain-containing; Domains: HAMP, HisKA, HATPase_c. (468 aa) |
| | cobU | Adenosylcobinamide kinase and adenosylcobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (174 aa) |
| | cobC | Adenosylcobalamin-5'-phosphate phosphatase, putative. (198 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (373 aa) |
| | gpmI | Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (512 aa) |
| | Gbem_3716 | Cytidylate kinase-like domain protein. (238 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (292 aa) |
| | Gbem_3629 | Sensor histidine kinase, PAS and GAF domain-containing, putative heme-binding site; Domains: PAS, GAF, HisKA, HATPase_c. (665 aa) |
| | Gbem_3616 | Sensor histidine kinase, HAMP domain-containing; Member of a two-component regulatory system. (489 aa) |
| | Gbem_3609 | Glycerate 2-kinase. (419 aa) |
| | gpmA | Phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (234 aa) |
| | Gbem_3464 | Sensor histidine kinase, HAMP domain-containing; Member of a two-component regulatory system. (482 aa) |
| | thiE/thiD | 4-amino-5-hydroxymethyl-2-methylpyrimidine- phosphate kinase and thiamin monophosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (484 aa) |
| | selD | Selenide, water dikinase, selenocysteine-containing; Synthesizes selenophosphate from selenide and ATP. (343 aa) |
| | pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (530 aa) |
| | Gbem_3405 | Sensor histidine kinase, GAF domain-containing; Domains: GAF, HisKA, HATPase_c. (540 aa) |
| | rluD | 23S rRNA pseudouridines 1911, 1915, 1917 synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (319 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (495 aa) |
| | Gbem_3366 | Sensor histidine kinase; Domains: HATPase_c. (374 aa) |
| | Gbem_3295 | Sensor histidine kinase, HAMP domain-containing; Domains: HAMP, HisKA, HATPase_c. (483 aa) |
| | cmk | Cytidylate kinase. (233 aa) |
| | pfk-4 | 6-phosphofructokinase, putative; Belongs to the carbohydrate kinase PfkB family. (311 aa) |
