(38 nodes) Porphyrin and chlorophyll metabolism network (Geobacter bemidjiensis)

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	Gbem_0015	Radical SAM domain iron-sulfur cluster-binding oxidoreductase. (358 aa)
	hemE	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (339 aa)
	hemH	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (317 aa)
	ctaB	Protoheme IX farnesyltransferase. (272 aa)
	Gbem_0218	Protoporphyrinogen oxidase-related protein. (399 aa)
	cysG	Precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase, putative. (224 aa)
	hemA	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (434 aa)
	hemC	Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (318 aa)
	hemD	Uroporphyrinogen III C2,C7-methyltransferase and uroporphyrinogen III synthase. (514 aa)
	hemB	Porphobilinogen synthase; Belongs to the ALAD family. (339 aa)
	Gbem_0465	Bacterioferritin, cytochrome b1; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (155 aa)
	Gbem_0897	Anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase; Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain and TPR domain. (564 aa)
	Gbem_1029	Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain. (472 aa)
	Gbem_1165	Anaerobic magnesium-protoporphyrin IX monomethyl ester oxidative cyclase-related enzyme. (506 aa)
	Gbem_1706	Dps-like bacterioferritin; Belongs to the Dps family. (167 aa)
	Gbem_1786	Radical SAM domain iron-sulfur cluster-binding oxidoreductase. (377 aa)
	gltX	glutamyl-tRNA synthetase, non-discriminating; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (467 aa)
	cobA-1	cob(I)yrinate a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (176 aa)
	cobA-2	cob(I)yrinate a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (176 aa)
	Gbem_3304	Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain. (487 aa)
	Gbem_3387	Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain. (557 aa)
	Gbem_3467	Anaerobic magnesium-protoporphyrin IX monomethyl ester oxidative cyclase-related enzyme. (506 aa)
	cobD	L-threonine-0-3-phosphate decarboxylase. (408 aa)
	cbiB	Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (319 aa)
	cbiH/cbiP	Cobalt-precorrin-3 C17-methyltransferase and adenosylcobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (776 aa)
	cbiG	cobalt-precorrin-5A hydrolase. (347 aa)
	cbiF	Cobalt-precorrin-4 C11-methyltransferase. (261 aa)
	cbiL	Cobalt-sirohydrochlorin C20-methyltransferase; Belongs to the precorrin methyltransferase family. (236 aa)
	cbiET	cobalt-precorrin-6B C5,C15-methyltransferase and C12-decarboxylase. (405 aa)
	cbiD	cobalt-precorrin-5B C1-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (356 aa)
	cbiC	cobalt-precorrin-8X methylmutase. (214 aa)
	cbiX	Sirohydrochlorin cobaltochelatase. (127 aa)
	cbiA	cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (462 aa)
	cobC	Adenosylcobalamin-5'-phosphate phosphatase, putative. (198 aa)
	cobS	Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (251 aa)
	cobT	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (350 aa)
	cobU	Adenosylcobinamide kinase and adenosylcobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (174 aa)
	hemL	Glutamate-1-semialdehyde 2,1-aminomutase. (427 aa)

Your Current Organism:

Geobacter bemidjiensis

NCBI taxonomy Id: 404380
Other names: G. bemidjiensis Bem, Geobacter bemidjiensis Bem, Geobacter bemidjiensis str. Bem, Geobacter bemidjiensis strain Bem

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Gbem_0015	Gbem_1786	Gbem_0015	Gbem_1786	Radical SAM domain iron-sulfur cluster-binding oxidoreductase.	Radical SAM domain iron-sulfur cluster-binding oxidoreductase.	0.927
Gbem_0015	ctaB	Gbem_0015	Gbem_0047	Radical SAM domain iron-sulfur cluster-binding oxidoreductase.	Protoheme IX farnesyltransferase.	0.900
Gbem_0015	hemD	Gbem_0015	Gbem_0409	Radical SAM domain iron-sulfur cluster-binding oxidoreductase.	Uroporphyrinogen III C2,C7-methyltransferase and uroporphyrinogen III synthase.	0.491
Gbem_0015	hemE	Gbem_0015	Gbem_0016	Radical SAM domain iron-sulfur cluster-binding oxidoreductase.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.585
Gbem_0015	hemH	Gbem_0015	Gbem_0039	Radical SAM domain iron-sulfur cluster-binding oxidoreductase.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.	0.917
Gbem_0218	hemD	Gbem_0218	Gbem_0409	Protoporphyrinogen oxidase-related protein.	Uroporphyrinogen III C2,C7-methyltransferase and uroporphyrinogen III synthase.	0.520
Gbem_0218	hemE	Gbem_0218	Gbem_0016	Protoporphyrinogen oxidase-related protein.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.983
Gbem_0218	hemH	Gbem_0218	Gbem_0039	Protoporphyrinogen oxidase-related protein.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.	0.977
Gbem_0465	Gbem_1706	Gbem_0465	Gbem_1706	Bacterioferritin, cytochrome b1; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.	Dps-like bacterioferritin; Belongs to the Dps family.	0.900
Gbem_0465	hemH	Gbem_0465	Gbem_0039	Bacterioferritin, cytochrome b1; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.	0.925
Gbem_0897	Gbem_1029	Gbem_0897	Gbem_1029	Anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase; Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain and TPR domain.	Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain.	0.749
Gbem_0897	Gbem_1165	Gbem_0897	Gbem_1165	Anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase; Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain and TPR domain.	Anaerobic magnesium-protoporphyrin IX monomethyl ester oxidative cyclase-related enzyme.	0.745
Gbem_0897	Gbem_3304	Gbem_0897	Gbem_3304	Anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase; Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain and TPR domain.	Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain.	0.733
Gbem_0897	Gbem_3387	Gbem_0897	Gbem_3387	Anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase; Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain and TPR domain.	Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain.	0.740
Gbem_0897	Gbem_3467	Gbem_0897	Gbem_3467	Anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase; Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain and TPR domain.	Anaerobic magnesium-protoporphyrin IX monomethyl ester oxidative cyclase-related enzyme.	0.746
Gbem_1029	Gbem_0897	Gbem_1029	Gbem_0897	Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain.	Anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase; Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain and TPR domain.	0.749
Gbem_1029	Gbem_1165	Gbem_1029	Gbem_1165	Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain.	Anaerobic magnesium-protoporphyrin IX monomethyl ester oxidative cyclase-related enzyme.	0.747
Gbem_1029	Gbem_3304	Gbem_1029	Gbem_3304	Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain.	Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain.	0.747
Gbem_1029	Gbem_3387	Gbem_1029	Gbem_3387	Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain.	Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain.	0.746
Gbem_1029	Gbem_3467	Gbem_1029	Gbem_3467	Radical SAM domain iron-sulfur cluster-binding oxidoreductase with cobalamin-binding-like domain.	Anaerobic magnesium-protoporphyrin IX monomethyl ester oxidative cyclase-related enzyme.	0.748