STRINGSTRING
SIS96208.1 SIS96208.1 SIS98808.1 SIS98808.1 SIT03889.1 SIT03889.1 pckA pckA SIT03464.1 SIT03464.1 SIT03656.1 SIT03656.1 accA accA SIT04750.1 SIT04750.1 SIT05038.1 SIT05038.1 SIT05444.1 SIT05444.1 SIT06387.1 SIT06387.1 SIT06692.1 SIT06692.1 SIT06702.1 SIT06702.1 SIT06759.1 SIT06759.1 SIT07495.1 SIT07495.1 SIT09448.1 SIT09448.1 SIT09997.1 SIT09997.1 SIT10936.1 SIT10936.1 SIT12250.1 SIT12250.1 SIS64459.1 SIS64459.1 SIS64233.1 SIS64233.1 SIS64221.1 SIS64221.1 SIS63784.1 SIS63784.1 SIS63775.1 SIS63775.1 SIS63203.1 SIS63203.1 SIS50069.1 SIS50069.1 glcB glcB SIS57790.1 SIS57790.1 SIS55546.1 SIS55546.1 SIS55182.1 SIS55182.1 SIS55080.1 SIS55080.1 SIS54756.1 SIS54756.1 accD accD fumC fumC SIS52799.1 SIS52799.1 SIS52679.1 SIS52679.1 SIS52540.1 SIS52540.1 SIT12279.1 SIT12279.1 SIT12290.1 SIT12290.1 SIT13632.1 SIT13632.1 SIT14268.1 SIT14268.1 SIT14819.1 SIT14819.1 SIT16421.1 SIT16421.1 SIT16434.1 SIT16434.1 SIT18144.1 SIT18144.1 SIT18413.1 SIT18413.1 acsA acsA SIS64719.1 SIS64719.1 mdh mdh SIS65539.1 SIS65539.1 SIS65640.1 SIS65640.1 SIS62115.1 SIS62115.1 SIS66510.1 SIS66510.1 SIS66936.1 SIS66936.1 SIS62460.1 SIS62460.1 SIS62601.1 SIS62601.1 leuA leuA SIS70434.1 SIS70434.1 SIS69252.1 SIS69252.1 SIS69283.1 SIS69283.1 SIS77210.1 SIS77210.1 SIS77988.1 SIS77988.1 SIS80485.1 SIS80485.1 SIS80703.1 SIS80703.1 SIS81470.1 SIS81470.1 SIS79492.1 SIS79492.1 SIS79819.1 SIS79819.1 SIS83555.1 SIS83555.1 SIS83566.1 SIS83566.1 pdhA pdhA SIS88050.1 SIS88050.1 gloB gloB SIS96065.1 SIS96065.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SIS96208.1Indolepyruvate ferredoxin oxidoreductase beta subunit. (515 aa)
SIS98808.1Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). (759 aa)
SIT03889.1Hypothetical protein. (118 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (531 aa)
SIT03464.1Aldehyde dehydrogenase (NAD+). (484 aa)
SIT03656.1acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa)
SIT04750.1Acetyl coenzyme A synthetase (ADP forming), alpha domain-containing protein. (708 aa)
SIT05038.1Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). (759 aa)
SIT05444.1D-lactate dehydrogenase (cytochrome). (458 aa)
SIT06387.1Catechol 2,3-dioxygenase. (132 aa)
SIT06692.1Mercuric reductase. (383 aa)
SIT06702.1Mercuric reductase. (87 aa)
SIT06759.1Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (716 aa)
SIT07495.1Phosphoenolpyruvate carboxylase, type 1; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (888 aa)
SIT09448.1Putative iron-dependent peroxidase. (320 aa)
SIT09997.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
SIT10936.1Hydroxyacylglutathione hydrolase. (287 aa)
SIT12250.1Hypothetical protein. (131 aa)
SIS64459.1PhnB protein. (145 aa)
SIS64233.1Biotin carboxylase /acetyl-CoA carboxylase carboxyltransferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
SIS64221.1Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (172 aa)
SIS63784.1Acetyl-CoA acetyltransferase. (383 aa)
SIS63775.16-carboxyhexanoate-CoA ligase. (705 aa)
SIS63203.1PhnB protein. (141 aa)
SIS50069.1UPF0716 protein FxsA. (176 aa)
glcBMalate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (718 aa)
SIS57790.1Hypothetical protein. (261 aa)
SIS55546.1Lactoylglutathione lyase. (131 aa)
SIS55182.1Pyruvate kinase; Belongs to the pyruvate kinase family. (481 aa)
SIS55080.1Phosphotransacetylase. (318 aa)
SIS54756.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (388 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (319 aa)
fumCFumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
SIS52799.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
SIS52679.1Hypothetical protein. (109 aa)
SIS52540.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (508 aa)
SIT12279.1acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (456 aa)
SIT12290.1Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (142 aa)
SIT13632.1Acyl-CoA synthetase (NDP forming). (683 aa)
SIT14268.1Glyoxylate/hydroxypyruvate reductase A. (310 aa)
SIT14819.1Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (791 aa)
SIT16421.1Hypothetical protein. (146 aa)
SIT16434.1Glyoxylate/hydroxypyruvate reductase A. (309 aa)
SIT18144.1Phosphoenolpyruvate carboxylase, type 1; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (884 aa)
SIT18413.1Propionate CoA-transferase. (671 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
SIS64719.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
SIS65539.1Dihydrolipoamide dehydrogenase. (464 aa)
SIS65640.1Pyruvate phosphate dikinase. (843 aa)
SIS62115.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1144 aa)
SIS66510.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (368 aa)
SIS66936.1Dihydrolipoamide dehydrogenase. (463 aa)
SIS62460.1Antibiotic biosynthesis monooxygenase. (107 aa)
SIS62601.1Glyoxylate/hydroxypyruvate reductase A. (302 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (525 aa)
SIS70434.1Glyoxylase, beta-lactamase superfamily II. (335 aa)
SIS69252.1Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (888 aa)
SIS69283.1Dihydrolipoamide dehydrogenase. (561 aa)
SIS77210.1D-lactate dehydrogenase (cytochrome). (459 aa)
SIS77988.1Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (787 aa)
SIS80485.1Hypothetical protein. (146 aa)
SIS80703.1Glyoxylase, beta-lactamase superfamily II. (340 aa)
SIS81470.1Glyoxalase family protein. (313 aa)
SIS79492.1acetyl-CoA synthetase. (517 aa)
SIS79819.1L-lactate dehydrogenase (cytochrome). (388 aa)
SIS83555.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (430 aa)
SIS83566.1Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (461 aa)
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (344 aa)
SIS88050.1Lactoylglutathione lyase. (142 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (248 aa)
SIS96065.1Acetyl-CoA acetyltransferase. (390 aa)
Your Current Organism:
Paracoccus saliphilus
NCBI taxonomy Id: 405559
Other names: CCTCC AB 206074, DSM 18447, KCTC 22163, P. saliphilus, Paracoccus saliphilus Wang et al. 2009, YIM 90738
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