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SMD14552.1 SMD14552.1 SMD14899.1 SMD14899.1 SMD14903.1 SMD14903.1 SMD15432.1 SMD15432.1 SMD15536.1 SMD15536.1 SMD20910.1 SMD20910.1 fumC fumC SMD23365.1 SMD23365.1 SMD23967.1 SMD23967.1 SMD25234.1 SMD25234.1 SMD25092.1 SMD25092.1 SMC55020.1 SMC55020.1 SMC65917.1 SMC65917.1 SMC65932.1 SMC65932.1 sucC sucC sucD sucD mdh mdh SMC67687.1 SMC67687.1 SMC67883.1 SMC67883.1 SMC67894.1 SMC67894.1 SMC67901.1 SMC67901.1 SMC67910.1 SMC67910.1 SMC69608.1 SMC69608.1 SMC78110.1 SMC78110.1 SMC88173.1 SMC88173.1 SMC88176.1 SMC88176.1 sucD-2 sucD-2 sucC-2 sucC-2 SMC96391.1 SMC96391.1 SMC97006.1 SMC97006.1 SMC97012.1 SMC97012.1 SMC97019.1 SMC97019.1 SMD02462.1 SMD02462.1 SMD03555.1 SMD03555.1 SMD08565.1 SMD08565.1 SMD08574.1 SMD08574.1 SMD08584.1 SMD08584.1 pckG pckG SMD13988.1 SMD13988.1 SMD14549.1 SMD14549.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMD14552.1Succinate dehydrogenase / fumarate reductase flavoprotein subunit. (622 aa)
SMD14899.1Dihydrolipoamide dehydrogenase. (462 aa)
SMD14903.12-oxoglutarate dehydrogenase E2 component. (579 aa)
SMD15432.1Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (919 aa)
SMD15536.1Dihydrolipoamide dehydrogenase. (449 aa)
SMD20910.1Succinate dehydrogenase / fumarate reductase flavoprotein subunit. (574 aa)
fumCFumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
SMD23365.1Citrate synthase; Belongs to the citrate synthase family. (437 aa)
SMD23967.1Dihydrolipoamide dehydrogenase. (461 aa)
SMD25234.1Aconitase. (646 aa)
SMD25092.1Aconitate hydratase. (938 aa)
SMC55020.1FAD dependent oxidoreductase. (531 aa)
SMC65917.12-oxoglutarate ferredoxin oxidoreductase subunit beta. (349 aa)
SMC65932.12-oxoglutarate ferredoxin oxidoreductase subunit alpha. (612 aa)
sucCsuccinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
sucDsuccinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (326 aa)
SMC67687.1Isocitrate dehydrogenase (NADP); Belongs to the isocitrate and isopropylmalate dehydrogenases family. (407 aa)
SMC67883.1Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. (260 aa)
SMC67894.1Succinate dehydrogenase subunit A. (584 aa)
SMC67901.1Succinate dehydrogenase / fumarate reductase membrane anchor subunit. (135 aa)
SMC67910.1Succinate dehydrogenase subunit C. (140 aa)
SMC69608.12-oxoglutarate decarboxylase. (1231 aa)
SMC78110.1Citrate synthase. (253 aa)
SMC88173.1Citrate synthase; Belongs to the citrate synthase family. (369 aa)
SMC88176.1Citrate synthase. (373 aa)
sucD-2succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa)
sucC-2succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (366 aa)
SMC96391.1Fumarase, class II. (476 aa)
SMC97006.1Pyruvate dehydrogenase E1 component alpha subunit. (358 aa)
SMC97012.1Pyruvate dehydrogenase E1 component beta subunit. (332 aa)
SMC97019.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (413 aa)
SMD02462.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1125 aa)
SMD03555.1Mycothione reductase. (457 aa)
SMD08565.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (459 aa)
SMD08574.1Pyruvate dehydrogenase E1 component beta subunit. (341 aa)
SMD08584.1Pyruvate dehydrogenase E1 component alpha subunit. (398 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (603 aa)
SMD13988.1Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (551 aa)
SMD14549.1Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. (249 aa)
Your Current Organism:
Lentzea albidocapillata
NCBI taxonomy Id: 40571
Other names: ATCC 51859, CCUG 48294, CIP 104842, DSM 44073, IFO 15855, IMMIB D-958, IMSNU 21253, JCM 9732, L. albidocapillata, Lentzea albidicapillata, NBRC 100372, NBRC 15855, NRRL B-24057, Saccharothrix albidicapillata, Saccharothrix albidocapillata
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