STRINGSTRING
SMD14123.1 SMD14123.1 SMD25361.1 SMD25361.1 SMD24850.1 SMD24850.1 SMD24686.1 SMD24686.1 SMD24248.1 SMD24248.1 SMD24126.1 SMD24126.1 SMD24030.1 SMD24030.1 SMD23967.1 SMD23967.1 SMD23046.1 SMD23046.1 SMD22622.1 SMD22622.1 SMD22519.1 SMD22519.1 SMD22455.1 SMD22455.1 fumC fumC SMD21562.1 SMD21562.1 SMD21422.1 SMD21422.1 SMD21404.1 SMD21404.1 leuA leuA SMD21328.1 SMD21328.1 SMD21327.1 SMD21327.1 acsA acsA SMD20940.1 SMD20940.1 SMD20828.1 SMD20828.1 SMD19866.1 SMD19866.1 SMD19716.1 SMD19716.1 SMD19296.1 SMD19296.1 SMD19226.1 SMD19226.1 SMD19168.1 SMD19168.1 SMD18276.1 SMD18276.1 SMD18226.1 SMD18226.1 SMD18074.1 SMD18074.1 SMD17654.1 SMD17654.1 SMD17515.1 SMD17515.1 SMD15536.1 SMD15536.1 SMD15432.1 SMD15432.1 SMD14899.1 SMD14899.1 SMD14280.1 SMD14280.1 SMD13988.1 SMD13988.1 SMD12634.1 SMD12634.1 SMD12504.1 SMD12504.1 SMD11656.1 SMD11656.1 SMD11646.1 SMD11646.1 SMD11304.1 SMD11304.1 SMD11167.1 SMD11167.1 pckG pckG SMD08584.1 SMD08584.1 SMD08574.1 SMD08574.1 SMD08565.1 SMD08565.1 SMD08495.1 SMD08495.1 SMD03555.1 SMD03555.1 SMD03542.1 SMD03542.1 SMD03163.1 SMD03163.1 SMD02727.1 SMD02727.1 SMD02462.1 SMD02462.1 SMD02140.1 SMD02140.1 SMD02008.1 SMD02008.1 SMD01953.1 SMD01953.1 SMC97316.1 SMC97316.1 SMC97019.1 SMC97019.1 SMC97012.1 SMC97012.1 SMC97006.1 SMC97006.1 SMC96391.1 SMC96391.1 SMC96077.1 SMC96077.1 SMC96064.1 SMC96064.1 SMC94975.1 SMC94975.1 SMC94970.1 SMC94970.1 ackA-2 ackA-2 SMC92823.1 SMC92823.1 SMC91402.1 SMC91402.1 SMC90762.1 SMC90762.1 SMC90016.1 SMC90016.1 SMC88318.1 SMC88318.1 SMC88226.1 SMC88226.1 SMC88069.1 SMC88069.1 SMC85595.1 SMC85595.1 ackA ackA SMC84428.1 SMC84428.1 SMC84160.1 SMC84160.1 SMC83838.1 SMC83838.1 SMC83203.1 SMC83203.1 SMC82526.1 SMC82526.1 SMC80735.1 SMC80735.1 SMC80513.1 SMC80513.1 SMC80324.1 SMC80324.1 SMC80116.1 SMC80116.1 SMC80011.1 SMC80011.1 SMC79980.1 SMC79980.1 SMC79784.1 SMC79784.1 SMC79146.1 SMC79146.1 SMC77575.1 SMC77575.1 SMC71799.1 SMC71799.1 SMC71020.1 SMC71020.1 SMC70820.1 SMC70820.1 SMC70043.1 SMC70043.1 SMC69400.1 SMC69400.1 SMC69261.1 SMC69261.1 SMC68591.1 SMC68591.1 SMC68157.1 SMC68157.1 mdh mdh SMC65932.1 SMC65932.1 SMC65917.1 SMC65917.1 SMC65327.1 SMC65327.1 SMC60247.1 SMC60247.1 SMC59916.1 SMC59916.1 SMC59595.1 SMC59595.1 SMC59093.1 SMC59093.1 SMC58863.1 SMC58863.1 SMC58850.1 SMC58850.1 SMC58430.1 SMC58430.1 SMC57265.1 SMC57265.1 SMC56625.1 SMC56625.1 SMC56480.1 SMC56480.1 SMC54122.1 SMC54122.1 SMC53638.1 SMC53638.1 SMC52265.1 SMC52265.1 SMC52165.1 SMC52165.1 SMC51443.1 SMC51443.1 SMC51330.1 SMC51330.1 SMC49865.1 SMC49865.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMD14123.1Acyl-CoA synthetase (NDP forming). (889 aa)
SMD25361.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
SMD24850.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
SMD24686.1Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family. (597 aa)
SMD24248.1Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (450 aa)
SMD24126.1Hypothetical protein. (121 aa)
SMD24030.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
SMD23967.1Dihydrolipoamide dehydrogenase. (461 aa)
SMD23046.1Hypothetical protein. (135 aa)
SMD22622.1Hypothetical protein. (127 aa)
SMD22519.1Malate dehydrogenase (oxaloacetate-decarboxylating). (460 aa)
SMD22455.1Hypothetical protein. (130 aa)
fumCFumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
SMD21562.1Rhodanese-related sulfurtransferase. (112 aa)
SMD21422.1Uncharacterized conserved protein PhnB, glyoxalase superfamily. (137 aa)
SMD21404.1ATP-grasp domain-containing protein. (475 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (607 aa)
SMD21328.1Glyoxylase, beta-lactamase superfamily II. (269 aa)
SMD21327.1Hypothetical protein. (260 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
SMD20940.1Protein of unknown function. (351 aa)
SMD20828.1PhnB protein. (135 aa)
SMD19866.1Hypothetical protein. (119 aa)
SMD19716.1Hypothetical protein. (198 aa)
SMD19296.1Hypothetical protein. (117 aa)
SMD19226.1FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase. (386 aa)
SMD19168.1Aldehyde dehydrogenase. (441 aa)
SMD18276.1Putative intracellular protease/amidase. (203 aa)
SMD18226.1Glyoxylase, beta-lactamase superfamily II. (447 aa)
SMD18074.1Glyoxylase, beta-lactamase superfamily II. (298 aa)
SMD17654.1Glyoxylase, beta-lactamase superfamily II. (199 aa)
SMD17515.1Glyoxylase, beta-lactamase superfamily II. (237 aa)
SMD15536.1Dihydrolipoamide dehydrogenase. (449 aa)
SMD15432.1Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (919 aa)
SMD14899.1Dihydrolipoamide dehydrogenase. (462 aa)
SMD14280.1Pyruvate, water dikinase. (842 aa)
SMD13988.1Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (551 aa)
SMD12634.1Pyruvate kinase; Belongs to the pyruvate kinase family. (441 aa)
SMD12504.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
SMD11656.1Hypothetical protein. (127 aa)
SMD11646.1Hypothetical protein. (130 aa)
SMD11304.1Hypothetical protein. (56 aa)
SMD11167.1Glyoxylase, beta-lactamase superfamily II. (225 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (603 aa)
SMD08584.1Pyruvate dehydrogenase E1 component alpha subunit. (398 aa)
SMD08574.1Pyruvate dehydrogenase E1 component beta subunit. (341 aa)
SMD08565.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (459 aa)
SMD08495.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
SMD03555.1Mycothione reductase. (457 aa)
SMD03542.1Uncharacterized conserved protein PhnB, glyoxalase superfamily. (134 aa)
SMD03163.1Hypothetical protein. (272 aa)
SMD02727.1Malate synthase; Belongs to the malate synthase family. (494 aa)
SMD02462.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1125 aa)
SMD02140.12-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (536 aa)
SMD02008.1Phosphoglycerate dehydrogenase. (304 aa)
SMD01953.1Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily protein. (120 aa)
SMC97316.1Putative resolvase. (191 aa)
SMC97019.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (413 aa)
SMC97012.1Pyruvate dehydrogenase E1 component beta subunit. (332 aa)
SMC97006.1Pyruvate dehydrogenase E1 component alpha subunit. (358 aa)
SMC96391.1Fumarase, class II. (476 aa)
SMC96077.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (384 aa)
SMC96064.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
SMC94975.1Rhodanese-related sulfurtransferase. (123 aa)
SMC94970.1Glyoxylase, beta-lactamase superfamily II. (462 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (370 aa)
SMC92823.1Deazaflavin-dependent oxidoreductase, nitroreductase family. (152 aa)
SMC91402.1Acetyl coenzyme A synthetase (ADP forming), alpha domain-containing protein. (715 aa)
SMC90762.1Hypothetical protein. (111 aa)
SMC90016.1Pyruvate, water dikinase. (742 aa)
SMC88318.1Deazaflavin-dependent oxidoreductase, nitroreductase family. (140 aa)
SMC88226.1Uncharacterized conserved protein PhnB, glyoxalase superfamily. (132 aa)
SMC88069.1Glyoxylase, beta-lactamase superfamily II. (329 aa)
SMC85595.1Malate dehydrogenase (oxaloacetate-decarboxylating). (252 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (368 aa)
SMC84428.1Catechol 2,3-dioxygenase. (140 aa)
SMC84160.1Uncharacterized conserved protein PhnB, glyoxalase superfamily. (129 aa)
SMC83838.1Hypothetical protein. (119 aa)
SMC83203.1Hypothetical protein. (197 aa)
SMC82526.1Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (472 aa)
SMC80735.1Pyruvate, phosphate dikinase. (448 aa)
SMC80513.1Predicted lactoylglutathione lyase. (242 aa)
SMC80324.1Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (501 aa)
SMC80116.1acetyl-CoA C-acetyltransferase. (380 aa)
SMC80011.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (375 aa)
SMC79980.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (376 aa)
SMC79784.1Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (297 aa)
SMC79146.1Hypothetical protein. (114 aa)
SMC77575.1acetyl-CoA carboxylase carboxyl transferase subunit beta. (448 aa)
SMC71799.1acetyl-CoA C-acetyltransferase. (392 aa)
SMC71020.1Uncharacterized conserved protein PhnB, glyoxalase superfamily. (157 aa)
SMC70820.1Pyruvate oxidase; Belongs to the TPP enzyme family. (585 aa)
SMC70043.1acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein. (637 aa)
SMC69400.1Malate dehydrogenase (oxaloacetate-decarboxylating). (398 aa)
SMC69261.1Hypothetical protein. (128 aa)
SMC68591.1acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein. (587 aa)
SMC68157.1Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (475 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (326 aa)
SMC65932.12-oxoglutarate ferredoxin oxidoreductase subunit alpha. (612 aa)
SMC65917.12-oxoglutarate ferredoxin oxidoreductase subunit beta. (349 aa)
SMC65327.1DNA binding domain-containing protein, excisionase family. (68 aa)
SMC60247.1Pyruvate, water dikinase. (702 aa)
SMC59916.1UPF0716 protein FxsA. (154 aa)
SMC59595.1Acyl-CoA synthetase (NDP forming). (662 aa)
SMC59093.1Hypothetical protein. (142 aa)
SMC58863.1Hypothetical protein. (116 aa)
SMC58850.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (507 aa)
SMC58430.1Putative intracellular protease/amidase. (214 aa)
SMC57265.1Hypothetical protein. (138 aa)
SMC56625.1Uncharacterized conserved protein PhnB, glyoxalase superfamily. (140 aa)
SMC56480.1Hypothetical protein. (117 aa)
SMC54122.1PhnB protein. (152 aa)
SMC53638.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
SMC52265.1Pyruvate, water dikinase. (876 aa)
SMC52165.1Hypothetical protein. (134 aa)
SMC51443.1Hypothetical protein. (125 aa)
SMC51330.1Hypothetical protein. (129 aa)
SMC49865.1Argininosuccinate lyase. (416 aa)
Your Current Organism:
Lentzea albidocapillata
NCBI taxonomy Id: 40571
Other names: ATCC 51859, CCUG 48294, CIP 104842, DSM 44073, IFO 15855, IMMIB D-958, IMSNU 21253, JCM 9732, L. albidocapillata, Lentzea albidicapillata, NBRC 100372, NBRC 15855, NRRL B-24057, Saccharothrix albidicapillata, Saccharothrix albidocapillata
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