STRINGSTRING
SMC69053.1 SMC69053.1 SMD24237.1 SMD24237.1 SMD24156.1 SMD24156.1 SMD24116.1 SMD24116.1 SMD24024.1 SMD24024.1 eno eno SMD23628.1 SMD23628.1 SMD23154.1 SMD23154.1 SMD23098.1 SMD23098.1 serC serC SMD22312.1 SMD22312.1 SMD21530.1 SMD21530.1 acsA acsA SMD21303.1 SMD21303.1 SMD21295.1 SMD21295.1 SMD21268.1 SMD21268.1 SMD20836.1 SMD20836.1 SMD19722.1 SMD19722.1 SMD17597.1 SMD17597.1 SMD17260.1 SMD17260.1 pfp pfp SMD14280.1 SMD14280.1 SMD14046.1 SMD14046.1 glyA-2 glyA-2 SMD11845.1 SMD11845.1 SMD08181.1 SMD08181.1 glyA glyA SMD07851.1 SMD07851.1 SMD07026.1 SMD07026.1 gpmA gpmA fbiD fbiD SMD02099.1 SMD02099.1 SMC97316.1 SMC97316.1 SMC97075.1 SMC97075.1 SMC96310.1 SMC96310.1 ackA-2 ackA-2 SMC91824.1 SMC91824.1 SMC90016.1 SMC90016.1 SMC87943.1 SMC87943.1 ackA ackA SMC84966.1 SMC84966.1 SMC84960.1 SMC84960.1 SMC82607.1 SMC82607.1 SMC81894.1 SMC81894.1 SMC80300.1 SMC80300.1 SMC80159.1 SMC80159.1 SMC69753.1 SMC69753.1 SMC69060.1 SMC69060.1 SMC67764.1 SMC67764.1 mdh mdh SMC65327.1 SMC65327.1 SMC60247.1 SMC60247.1 SMC58863.1 SMC58863.1 SMC52265.1 SMC52265.1 SMC49305.1 SMC49305.1 SMC48630.1 SMC48630.1 SMC48507.1 SMC48507.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMC69053.1Coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase. (440 aa)
SMD24237.12-phosphosulfolactate phosphatase. (223 aa)
SMD24156.1Oxidoreductase alpha (molybdopterin) subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (762 aa)
SMD24116.1Probable phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (201 aa)
SMD24024.1Histidine phosphatase superfamily (branch 1). (139 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
SMD23628.1Broad specificity phosphatase PhoE; Belongs to the phosphoglycerate mutase family. (215 aa)
SMD23154.1Conserved hypothetical protein, cofD-related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (325 aa)
SMD23098.1F420-dependent oxidoreductase, CPS_4043 family. (330 aa)
serCPhosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (375 aa)
SMD22312.1Fructose-1,6-bisphosphatase II. (346 aa)
SMD21530.1VWA domain containing CoxE-like protein. (380 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
SMD21303.1Transcriptional regulator, RpiR family. (306 aa)
SMD21295.1HAD-superfamily subfamily IB hydrolase, TIGR01490. (264 aa)
SMD21268.1Probable F420-dependent oxidoreductase, MSMEG_2256 family. (320 aa)
SMD20836.1Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (311 aa)
SMD19722.1Phosphoserine phosphatase. (404 aa)
SMD17597.1Luciferase-like monooxygenase. (252 aa)
SMD17260.1Anaerobic selenocysteine-containing dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (712 aa)
pfp6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (342 aa)
SMD14280.1Pyruvate, water dikinase. (842 aa)
SMD14046.1Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD. (439 aa)
glyA-2Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (421 aa)
SMD11845.1Type I phosphodiesterase / nucleotide pyrophosphatase. (486 aa)
SMD08181.1Fe-S oxidoreductase. (753 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (405 aa)
SMD07851.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (344 aa)
SMD07026.1Hypothetical protein. (301 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
fbiD2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. (212 aa)
SMD02099.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
SMC97316.1Putative resolvase. (191 aa)
SMC97075.1Fructose-bisphosphate aldolase, class II. (273 aa)
SMC96310.1Probable F420-dependent oxidoreductase, MSMEG_2256 family. (341 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (370 aa)
SMC91824.15,6,7,8-tetrahydromethanopterin hydro-lyase. (167 aa)
SMC90016.1Pyruvate, water dikinase. (742 aa)
SMC87943.1Probable F420-dependent oxidoreductase, Rv3093c family. (316 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (368 aa)
SMC84966.1Probable F420-dependent oxidoreductase, Rv3520c family. (349 aa)
SMC84960.1Probable phosphomutase, MSMEG_4193 family. (230 aa)
SMC82607.1Ca-activated chloride channel family protein. (777 aa)
SMC81894.1Iron-binding zinc finger CDGSH type. (75 aa)
SMC80300.1S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase. (361 aa)
SMC80159.1Probable F420-dependent oxidoreductase, Rv3520c family. (342 aa)
SMC69753.1TROVE domain-containing protein. (529 aa)
SMC69060.1LPPG:FO 2-phospho-L-lactate transferase. (323 aa)
SMC67764.1FO synthase subunit 1 /FO synthase subunit 2. (822 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (326 aa)
SMC65327.1DNA binding domain-containing protein, excisionase family. (68 aa)
SMC60247.1Pyruvate, water dikinase. (702 aa)
SMC58863.1Hypothetical protein. (116 aa)
SMC52265.1Pyruvate, water dikinase. (876 aa)
SMC49305.1Molydopterin dinucleotide binding domain-containing protein. (255 aa)
SMC48630.1Glutamate synthase conserved region-containing protein. (420 aa)
SMC48507.1Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (335 aa)
Your Current Organism:
Lentzea albidocapillata
NCBI taxonomy Id: 40571
Other names: ATCC 51859, CCUG 48294, CIP 104842, DSM 44073, IFO 15855, IMMIB D-958, IMSNU 21253, JCM 9732, L. albidocapillata, Lentzea albidicapillata, NBRC 100372, NBRC 15855, NRRL B-24057, Saccharothrix albidicapillata, Saccharothrix albidocapillata
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