STRINGSTRING
SACE_2695 SACE_2695 acpP-2 acpP-2 SACE_5532 SACE_5532 SACE_4923 SACE_4923 SACE_4476 SACE_4476 pteA1 pteA1 SACE_4288 SACE_4288 SACE_4287 SACE_4287 SACE_4285 SACE_4285 SACE_4141 SACE_4141 SACE_4140 SACE_4140 SACE_4139 SACE_4139 acpP acpP SACE_3224 SACE_3224 SACE_3035 SACE_3035 SACE_2875 SACE_2875 SACE_2696 SACE_2696 SACE_2693 SACE_2693 SACE_2630 SACE_2630 SACE_2629 SACE_2629 SACE_2620 SACE_2620 SACE_1305 SACE_1305 eryAIII eryAIII eryAII eryAII eryAI eryAI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SACE_2695Putative non-ribosomal peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family. (1583 aa)
acpP-2Probable acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (79 aa)
SACE_5532Iterative type I polyketide synthase. (1738 aa)
SACE_4923Hypothetical protein; Non-ribosomal peptide synthetase modules. (532 aa)
SACE_4476Multi-domain beta-ketoacyl synthase. (1568 aa)
pteA1Modular polyketide synthase. (1438 aa)
SACE_4288Putative non-ribosomal peptide synthetase. (7259 aa)
SACE_4287Putative non-ribosomal peptide synthetase. (3337 aa)
SACE_4285AMP-dependent synthetase and ligase. (1260 aa)
SACE_4141Type I modular polyketide synthase. (4327 aa)
SACE_4140Type I modular polyketide synthase. (3481 aa)
SACE_4139Type I modular polyketide synthase. (5359 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (95 aa)
SACE_3224Non-ribosomal peptide synthetase modules. (1315 aa)
SACE_3035Putative non-ribosomal peptide synthetase. (5429 aa)
SACE_2875Modular polyketide synthase-; Modular PKS with 1 AHBA loading domain similar to GdmAI, and two extension modules, first module has complete set of the reductive domains, and the other one didn't have any reductive domains. Found by M.Oliynyk and sequenced by M.Samborskyy (M0ERY) in 2004/02. If it is active, than it can be responsible for the production of the aromatic poliketide antibiotic with low molecular weight. Thanks to the B. Ostash, A. Luzhetsky and Y. Rebets for help with annotation of this cluster in 2004. (4132 aa)
SACE_2696Putative non-ribosomal peptide synthetase. (2385 aa)
SACE_2693Non-ribosomal peptide synthase. (1167 aa)
SACE_2630Modular polyketide synthase. (4576 aa)
SACE_2629Modular ype I polyketide synthase. (2117 aa)
SACE_2620Modular polyketide synthase; Similar to StiA and MxaF proteins from Stigmatella aurantiaca. (1522 aa)
SACE_1305Putative non-ribosomal peptide synthetase. (1767 aa)
eryAIIIEryAIII Erythromycin polyketide synthase modules 5 and 6. (3171 aa)
eryAIIEryAII Erythromycin polyketide synthase modules 3 and 4; DEBS2. (3567 aa)
eryAIEryAI Erythromycin polyketide synthase modules 1 and 2; DEBS1. (3545 aa)
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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