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lipA lipA NJ7G_0036 NJ7G_0036 NJ7G_0008 NJ7G_0008 NJ7G_4362 NJ7G_4362 NJ7G_4222 NJ7G_4222 NJ7G_4217 NJ7G_4217 NJ7G_4208 NJ7G_4208 NJ7G_4196 NJ7G_4196 NJ7G_4126 NJ7G_4126 NJ7G_4111 NJ7G_4111 hutI hutI hutU hutU aroE aroE cofC cofC gpmI gpmI NJ7G_3824 NJ7G_3824 NJ7G_3800 NJ7G_3800 NJ7G_3779 NJ7G_3779 NJ7G_3667 NJ7G_3667 NJ7G_3657 NJ7G_3657 NJ7G_3655 NJ7G_3655 NJ7G_3586 NJ7G_3586 NJ7G_3585 NJ7G_3585 NJ7G_3549 NJ7G_3549 NJ7G_3547 NJ7G_3547 NJ7G_3538 NJ7G_3538 NJ7G_3490 NJ7G_3490 NJ7G_3489 NJ7G_3489 NJ7G_3486 NJ7G_3486 NJ7G_3455 NJ7G_3455 NJ7G_3395 NJ7G_3395 NJ7G_3393 NJ7G_3393 NJ7G_3373 NJ7G_3373 NJ7G_3355 NJ7G_3355 NJ7G_3347 NJ7G_3347 pgk pgk NJ7G_3289 NJ7G_3289 NJ7G_3176 NJ7G_3176 NJ7G_3155 NJ7G_3155 NJ7G_3032 NJ7G_3032 cofE cofE NJ7G_2839 NJ7G_2839 NJ7G_2767 NJ7G_2767 NJ7G_2764 NJ7G_2764 pgi pgi NJ7G_2709 NJ7G_2709 NJ7G_2557 NJ7G_2557 NJ7G_2517 NJ7G_2517 NJ7G_2315 NJ7G_2315 NJ7G_2020 NJ7G_2020 NJ7G_1963 NJ7G_1963 NJ7G_1947 NJ7G_1947 NJ7G_1943 NJ7G_1943 NJ7G_1940 NJ7G_1940 NJ7G_1931 NJ7G_1931 NJ7G_1919 NJ7G_1919 NJ7G_1916 NJ7G_1916 NJ7G_1914 NJ7G_1914 NJ7G_1908 NJ7G_1908 NJ7G_1906 NJ7G_1906 NJ7G_1904 NJ7G_1904 NJ7G_1902 NJ7G_1902 NJ7G_1893 NJ7G_1893 NJ7G_1890 NJ7G_1890 NJ7G_1709 NJ7G_1709 NJ7G_1672 NJ7G_1672 NJ7G_1617 NJ7G_1617 NJ7G_1532 NJ7G_1532 NJ7G_1486 NJ7G_1486 NJ7G_1338 NJ7G_1338 NJ7G_1300 NJ7G_1300 NJ7G_1296 NJ7G_1296 NJ7G_1278 NJ7G_1278 NJ7G_1216 NJ7G_1216 NJ7G_1202 NJ7G_1202 NJ7G_1141 NJ7G_1141 NJ7G_1123 NJ7G_1123 NJ7G_1120 NJ7G_1120 eno eno panB panB NJ7G_1012 NJ7G_1012 NJ7G_0832 NJ7G_0832 bioB bioB NJ7G_0816 NJ7G_0816 bioD bioD NJ7G_0788 NJ7G_0788 NJ7G_0784 NJ7G_0784 tpiA tpiA cofD cofD NJ7G_0680 NJ7G_0680 NJ7G_0659 NJ7G_0659 NJ7G_0580 NJ7G_0580 NJ7G_0388 NJ7G_0388 NJ7G_0348 NJ7G_0348 NJ7G_0288 NJ7G_0288 gap gap NJ7G_0204 NJ7G_0204 NJ7G_0182 NJ7G_0182 NJ7G_0174 NJ7G_0174 NJ7G_0158 NJ7G_0158 NJ7G_0153 NJ7G_0153 NJ7G_0117 NJ7G_0117 NJ7G_0116 NJ7G_0116 NJ7G_0114 NJ7G_0114 NJ7G_0113 NJ7G_0113 NJ7G_0107 NJ7G_0107
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lipALipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (325 aa)
NJ7G_0036Pyruvate dehydrogenase E1 component, alpha subunit. (308 aa)
NJ7G_0008Dihydrolipoamide dehydrogenase. (488 aa)
NJ7G_4362Butyryl-CoA dehydrogenase. (374 aa)
NJ7G_4222Beta-lactamase domain protein. (280 aa)
NJ7G_4217Amidohydrolase. (535 aa)
NJ7G_4208Isocitrate dehydrogenase, NADP-dependent. (436 aa)
NJ7G_4196Pyruvate kinase; Belongs to the pyruvate kinase family. (585 aa)
NJ7G_4126Trimethylamine-N-oxide reductase. (831 aa)
NJ7G_4111Histidine ammonia-lyase. (524 aa)
hutIImidazolonepropionase; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (405 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (576 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (269 aa)
cofC2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (236 aa)
gpmIPhosphoglycerate mutase, 2,3-bisphosphoglycerate- independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (506 aa)
NJ7G_3824Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase. (390 aa)
NJ7G_3800Beta-lactamase domain protein. (375 aa)
NJ7G_3779Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (780 aa)
NJ7G_3667Propanoyl-CoA C-acyltransferase. (388 aa)
NJ7G_3657acyl-CoA dehydrogenase domain-containing protein. (381 aa)
NJ7G_3655AMP-dependent synthetase and ligase. (566 aa)
NJ7G_3586MaoC domain protein dehydratase. (141 aa)
NJ7G_3585Hypothetical protein. (41 aa)
NJ7G_3549acetate/CoA ligase. (666 aa)
NJ7G_3547acetate/CoA ligase. (659 aa)
NJ7G_3538Beta-lactamase domain protein. (336 aa)
NJ7G_3490acyl-CoA dehydrogenase domain-containing protein. (381 aa)
NJ7G_34893-hydroxyacyl-CoA dehydrogenase NAD-binding protein; Belongs to the enoyl-CoA hydratase/isomerase family. (657 aa)
NJ7G_3486acyl-CoA dehydrogenase domain-containing protein. (383 aa)
NJ7G_3455Enoyl-CoA hydratase/isomerase. (254 aa)
NJ7G_3395Propanoyl-CoA C-acyltransferase. (385 aa)
NJ7G_3393propanoyl-CoA C-acyltransferase. (376 aa)
NJ7G_3373Carboxyl transferase. (516 aa)
NJ7G_3355Thioesterase superfamily protein. (149 aa)
NJ7G_3347Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (489 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (407 aa)
NJ7G_3289HpcH/HpaI aldolase. (347 aa)
NJ7G_3176F420-dependent oxidoreductase, G6PDH family. (318 aa)
NJ7G_3155Hypothetical protein. (168 aa)
NJ7G_3032Isochorismate synthase. (447 aa)
cofEF420-dependent oxidoreductase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. (256 aa)
NJ7G_2839AMP-dependent synthetase and ligase. (553 aa)
NJ7G_2767Electron transfer flavoprotein alpha subunit. (318 aa)
NJ7G_2764Beta-lactamase domain protein. (330 aa)
pgiPhosphoglucose isomerase; Belongs to the GPI family. (431 aa)
NJ7G_2709Mandelate racemase/muconate lactonizing protein. (444 aa)
NJ7G_25576-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH. (299 aa)
NJ7G_2517Fumarylacetoacetate hydrolase. (331 aa)
NJ7G_2315Propanoyl-CoA C-acyltransferase. (436 aa)
NJ7G_20203-hydroxyacyl-CoA dehydrogenase NAD-binding protein; Belongs to the enoyl-CoA hydratase/isomerase family. (650 aa)
NJ7G_1963MaoC domain protein dehydratase. (158 aa)
NJ7G_1947Aldehyde Dehydrogenase. (510 aa)
NJ7G_1943Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
NJ7G_1940Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (436 aa)
NJ7G_1931acyl-CoA hydrolase. (97 aa)
NJ7G_1919Monoamine oxidase regulatory protein. (153 aa)
NJ7G_1916phenylacetate-CoA oxygenase, PaaI subunit. (278 aa)
NJ7G_1914Phenylacetic acid catabolic family protein. (312 aa)
NJ7G_1908phenylacetate--CoA ligase. (435 aa)
NJ7G_1906methylmalonyl-CoA mutase large subunit. (566 aa)
NJ7G_1904AMP-dependent synthetase and ligase. (544 aa)
NJ7G_19023-hydroxyacyl-CoA dehydrogenase NAD-binding protein. (287 aa)
NJ7G_1893AMP-dependent synthetase and ligase. (612 aa)
NJ7G_1890MaoC domain protein dehydratase. (154 aa)
NJ7G_1709MaoC domain protein dehydratase. (128 aa)
NJ7G_1672Beta-lactamase domain-containing protein. (238 aa)
NJ7G_1617Fumarylacetoacetate hydrolase. (253 aa)
NJ7G_1532Chorismate mutase. (110 aa)
NJ7G_1486MaoC domain protein dehydratase. (212 aa)
NJ7G_1338Glyoxalase/bleomycin resistance protein/dioxygenase. (262 aa)
NJ7G_1300Beta-lactamase domain protein. (238 aa)
NJ7G_1296Hypothetical protein. (192 aa)
NJ7G_1278MaoC domain protein dehydratase. (150 aa)
NJ7G_1216FAD linked oxidase domain protein. (475 aa)
NJ7G_1202methylmalonyl-CoA mutase, large subunit. (560 aa)
NJ7G_1141Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (505 aa)
NJ7G_1123Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (493 aa)
NJ7G_1120Hypothetical protein. (45 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (401 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (272 aa)
NJ7G_1012Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (483 aa)
NJ7G_08325-carboxymethyl-2-hydroxymuconate Delta-isomerase. (245 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (367 aa)
NJ7G_08168-amino-7-oxononanoate synthase. (407 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (235 aa)
NJ7G_0788ThiJ/PfpI domain-containing protein. (264 aa)
NJ7G_0784Propanoyl-CoA C-acyltransferase. (392 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (214 aa)
cofDLPPG domain protein containing protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. (330 aa)
NJ7G_0680Enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (234 aa)
NJ7G_0659Hypothetical protein. (336 aa)
NJ7G_0580Thioesterase superfamily protein. (145 aa)
NJ7G_03882-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (302 aa)
NJ7G_0348Creatininase. (257 aa)
NJ7G_0288MaoC domain protein dehydratase. (311 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase, type II. (338 aa)
NJ7G_0204Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (503 aa)
NJ7G_0182AMP-dependent synthetase and ligase. (673 aa)
NJ7G_0174acetyl-CoA acetyltransferase. (378 aa)
NJ7G_0158MaoC domain protein dehydratase. (340 aa)
NJ7G_0153Enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (265 aa)
NJ7G_0117D-lactate dehydrogenase. (1024 aa)
NJ7G_01163-hydroxyacyl-CoA dehydrogenase. (350 aa)
NJ7G_0114acetyl-CoA acetyltransferase. (380 aa)
NJ7G_0113acyl-CoA dehydrogenase domain-containing protein. (379 aa)
NJ7G_0107acyl-CoA dehydrogenase domain-containing protein. (387 aa)
Your Current Organism:
Natrinema sp. J72
NCBI taxonomy Id: 406552
Other names: N. sp. J7-2, Natrinema sp. J7-2
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