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| | NJ7G_0008 | Dihydrolipoamide dehydrogenase. (488 aa) |
| | NJ7G_0034 | Dihydrolipoyllysine-residue acetyltransferase. (551 aa) |
| | NJ7G_0035 | Pyruvate dehydrogenase E1 component,subunit beta. (329 aa) |
| | NJ7G_0036 | Pyruvate dehydrogenase E1 component, alpha subunit. (308 aa) |
| | NJ7G_0071 | Prephenate dehydratase. (270 aa) |
| | NJ7G_0107 | acyl-CoA dehydrogenase domain-containing protein. (387 aa) |
| | NJ7G_0114 | acetyl-CoA acetyltransferase. (380 aa) |
| | NJ7G_0138 | dTDP-glucose 4,6-dehydratase-related protein. (305 aa) |
| | NJ7G_0151 | Anthranilate phosphoribosyltransferase. (360 aa) |
| | NJ7G_0174 | acetyl-CoA acetyltransferase. (378 aa) |
| | NJ7G_0204 | Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (503 aa) |
| | gap | Glyceraldehyde-3-phosphate dehydrogenase, type II. (338 aa) |
| | NJ7G_0255 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (419 aa) |
| | argF | Ornithine carbamoyltransferase. (306 aa) |
| | NJ7G_0260 | Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (384 aa) |
| | lysZ | Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. (285 aa) |
| | lysY | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (358 aa) |
| | argH | Argininosuccinate lyase. (512 aa) |
| | argG | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (419 aa) |
| | NJ7G_0328 | L-lysine 6-monooxygenase. (490 aa) |
| | NJ7G_0329 | Siderophore biosynthesis protein, conserved region. (221 aa) |
| | NJ7G_0359 | Alcohol dehydrogenase GroES domain protein. (353 aa) |
| | NJ7G_0364 | Porphobilinogen synthase; Belongs to the ALAD family. (337 aa) |
| | hemL | Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (448 aa) |
| | NJ7G_0370 | Porphobilinogen deaminase. (379 aa) |
| | NJ7G_0371 | uroporphyrin-III C-methyltransferase. (265 aa) |
| | NJ7G_0372 | Uroporphyrinogen III synthase HEM4. (247 aa) |
| | NJ7G_0388 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (302 aa) |
| | NJ7G_0417 | Lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily. (299 aa) |
| | purO | IMP cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP. (227 aa) |
| | NJ7G_0429 | Serine O-acetyltransferase. (171 aa) |
| | fni | Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (353 aa) |
| | rpiA | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (235 aa) |
| | NJ7G_0456 | Cytidyltransferase-related domain protein. (163 aa) |
| | NJ7G_0474 | Aspartate kinase; Belongs to the aspartokinase family. (392 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase. (195 aa) |
| | hisA | 1--5- imidazole-4-carboxamide isomerase. (250 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (285 aa) |
| | NJ7G_0552 | Phosphoglucosamine mutase. (458 aa) |
| | hisI | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (122 aa) |
| | NJ7G_0555 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa) |
| | NJ7G_0559 | HAD-superfamily hydrolase, subfamily IB. (237 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (401 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (286 aa) |
| | NJ7G_0760 | Aspartate-semialdehyde dehydrogenase. (344 aa) |
| | hisC | Histidinol-phosphate aminotransferase. (384 aa) |
| | NJ7G_0771 | Adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (184 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (214 aa) |
| | NJ7G_0783 | Hypothetical protein. (507 aa) |
| | NJ7G_0784 | Propanoyl-CoA C-acyltransferase. (392 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (500 aa) |
| | rbcL | Ribulose bisphosphate carboxylase, type III; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (421 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa) |
| | sucC | succinyl-CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (383 aa) |
| | NJ7G_0840 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase. (127 aa) |
| | NJ7G_0853 | Arginase; Belongs to the arginase family. (306 aa) |
| | NJ7G_0905 | Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (264 aa) |
| | NJ7G_0919 | Inositol monophosphatase. (267 aa) |
| | NJ7G_0954 | Hypothetical protein. (292 aa) |
| | NJ7G_1014 | Alcohol dehydrogenase zinc-binding domain protein. (353 aa) |
| | NJ7G_1075 | HAD-superfamily hydrolase, subfamily IA, variant 1. (193 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (272 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (401 aa) |
| | mvk | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (328 aa) |
| | NJ7G_1104 | Aspartate/glutamate/uridylate kinase; Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids. (246 aa) |
| | NJ7G_1113 | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (350 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (638 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa) |
| | gcvT | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (379 aa) |
| | NJ7G_1123 | Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (493 aa) |
| | NJ7G_1135 | Hydroxymethylglutaryl-CoA synthase. (445 aa) |
| | NJ7G_1139 | Glycine dehydrogenase. (424 aa) |
| | NJ7G_1140 | Aminotransferase class V. (503 aa) |
| | NJ7G_1141 | Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (505 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (154 aa) |
| | NJ7G_1165 | Cys/Met metabolism pyridoxal-phosphate-dependent protein. (388 aa) |
| | NJ7G_1175 | Cobalamin-independent synthase MetE domain protein. (335 aa) |
| | NJ7G_1176 | Methionine synthase vitamin-B12 independent. (358 aa) |
| | NJ7G_1196 | HAD-superfamily hydrolase, subfamily IA, variant 1. (217 aa) |
| | NJ7G_1208 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (527 aa) |
| | NJ7G_1209 | Pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit. (288 aa) |
| | NJ7G_1211 | Aminotransferase class I and II. (385 aa) |
| | NJ7G_1219 | Hypothetical protein. (286 aa) |
| | ribL | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (175 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (575 aa) |
| | NJ7G_1312 | Aminotransferase class I and II. (366 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (490 aa) |
| | NJ7G_1389 | Oxidoreductase domain protein. (371 aa) |
| | NJ7G_1434 | Alpha,alpha-trehalose-phosphate synthase. (459 aa) |
| | NJ7G_1435 | Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. (272 aa) |
| | NJ7G_1450 | FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (410 aa) |
| | NJ7G_1491 | Short-chain dehydrogenase/reductase SDR. (247 aa) |
| | NJ7G_1505 | Nucleotidyl transferase. (365 aa) |
| | NJ7G_1532 | Chorismate mutase. (110 aa) |
| | aroK | Shikimate kinase. (290 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (338 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (216 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (562 aa) |
| | NJ7G_1566 | Glutamine amidotransferase. (215 aa) |
| | NJ7G_1607 | Phytoene synthase. (317 aa) |
| | NJ7G_1613 | Short-chain dehydrogenase/reductase SDR. (232 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (220 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (311 aa) |
| | NJ7G_1687 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (240 aa) |
| | NJ7G_1708 | SPP-like hydrolase; Catalyzes the dephosphorylation of 2-phosphoglycolate. (236 aa) |
| | NJ7G_1715 | Glycerol-3-phosphate dehydrogenase, anaerobic, A subunit. (579 aa) |
| | NJ7G_1716 | Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit. (434 aa) |
| | NJ7G_1717 | Glycerol-3-phosphate dehydrogenase, anaerobic, C subunit. (442 aa) |
| | NJ7G_1731 | Nucleotidyl transferase. (244 aa) |
| | NJ7G_1743 | Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (418 aa) |
| | NJ7G_1744 | Acetolactate synthase, large subunit, biosynthetic type. (594 aa) |
| | NJ7G_1745 | Acetolactate synthase, small subunit. (220 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (351 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (473 aa) |
| | NJ7G_1749 | 3-isopropylmalate dehydratase, small subunit. (211 aa) |
| | NJ7G_1752 | 3-isopropylmalate dehydrogenase. (326 aa) |
| | NJ7G_1887 | AMP-dependent synthetase and ligase. (665 aa) |
| | NJ7G_1891 | Carbamoyl-phosphate synthase L chain ATP-binding protein. (590 aa) |
| | NJ7G_1892 | acyl-CoA dehydrogenase domain-containing protein. (378 aa) |
| | NJ7G_1893 | AMP-dependent synthetase and ligase. (612 aa) |
| | NJ7G_1894 | Hypothetical protein. (464 aa) |
| | NJ7G_1895 | Carboxylyase-related protein. (501 aa) |
| | NJ7G_1904 | AMP-dependent synthetase and ligase. (544 aa) |
| | NJ7G_1947 | Aldehyde Dehydrogenase. (510 aa) |
| | NJ7G_1949 | Thiamine pyrophosphate central domain-containing protein; Belongs to the TPP enzyme family. (548 aa) |
| | NJ7G_1955 | Proline dehydrogenase. (279 aa) |
| | NJ7G_1990 | Threonine synthase. (396 aa) |
| | NJ7G_2010 | Short-chain dehydrogenase/reductase SDR. (258 aa) |
| | NJ7G_2015 | Alcohol dehydrogenase. (357 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (211 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (445 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (277 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (247 aa) |
| | NJ7G_2107 | Phosphatidylserine decarboxylase. (331 aa) |
| | NJ7G_2180 | Pyridoxal-5'-phosphate-dependent protein beta subunit. (391 aa) |
| | NJ7G_2196 | Lycopene beta and epsilon cyclase. (549 aa) |
| | NJ7G_2201 | Threonine dehydratase. (403 aa) |
| | NJ7G_2202 | 2-methylcitrate synthase/citrate synthase II. (382 aa) |
| | NJ7G_2238 | GMP reductase. (376 aa) |
| | NJ7G_2312 | Thiamine pyrophosphate central domain-containing protein; Belongs to the TPP enzyme family. (547 aa) |
| | NJ7G_2315 | Propanoyl-CoA C-acyltransferase. (436 aa) |
| | NJ7G_2316 | Hypothetical protein. (475 aa) |
| | NJ7G_2409 | Homoserine dehydrogenase. (315 aa) |
| | NJ7G_2413 | ROK family protein. (325 aa) |
| | NJ7G_2417 | Short-chain dehydrogenase/reductase SDR. (246 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (292 aa) |
| | NJ7G_2493 | Undecaprenyl diphosphate synthase. (210 aa) |
| | NJ7G_2498 | Siroheme synthase. (218 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (448 aa) |
| | NJ7G_2502 | Haloacid dehalogenase. (211 aa) |
| | NJ7G_2552 | Aconitate hydratase. (657 aa) |
| | NJ7G_2557 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH. (299 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (383 aa) |
| | NJ7G_2654 | Folate-binding protein YgfZ. (363 aa) |
| | NJ7G_2677 | Isopentenyl-diphosphate Delta-isomerase. (186 aa) |
| | pgi | Phosphoglucose isomerase; Belongs to the GPI family. (431 aa) |
| | NJ7G_2749 | Riboflavin synthase subunit alpha. (201 aa) |
| | NJ7G_2771 | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (280 aa) |
| | NJ7G_2779 | Methyltransferase type 11. (207 aa) |
| | NJ7G_2809 | Peptidase M20. (367 aa) |
| | NJ7G_2815 | Lycopene cyclase domain protein. (260 aa) |
| | NJ7G_2839 | AMP-dependent synthetase and ligase. (553 aa) |
| | NJ7G_2851 | Asparaginase/glutaminase. (335 aa) |
| | hisE | phosphoribosyl-ATP diphosphatase. (94 aa) |
| | NJ7G_2889 | Citrate synthase. (377 aa) |
| | NJ7G_2890 | Citrate synthase; Belongs to the citrate synthase family. (501 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (432 aa) |
| | NJ7G_2948 | Serine--pyruvate transaminase. (410 aa) |
| | fumC | Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (471 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (271 aa) |
| | NJ7G_3032 | Isochorismate synthase. (447 aa) |
| | menD | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). (606 aa) |
| | NJ7G_3047 | Phosphoenolpyruvate carboxykinase. (503 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (716 aa) |
| | NJ7G_3072 | Asparagine synthase. (376 aa) |
| | ctaB | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (476 aa) |
| | NJ7G_3103 | O-succinylbenzoate-CoA ligase. (540 aa) |
| | menA | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (314 aa) |
| | menB | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. (386 aa) |
| | NJ7G_3135 | CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (241 aa) |
| | surE | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (279 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (452 aa) |
| | NJ7G_3246 | Diphosphomevalonate decarboxylase. (322 aa) |
| | NJ7G_3252 | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (354 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (407 aa) |
| | NJ7G_3345 | PfkB domain protein. (354 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase. (331 aa) |
| | NJ7G_3373 | Carboxyl transferase. (516 aa) |
| | NJ7G_3374 | Hypothetical protein. (109 aa) |
| | NJ7G_3376 | Carbamoyl-phosphate synthase L chain ATP-binding protein. (611 aa) |
| | NJ7G_3377 | Radical SAM domain protein. (377 aa) |
| | NJ7G_3379 | Radical SAM domain protein. (402 aa) |
| | NJ7G_3393 | propanoyl-CoA C-acyltransferase. (376 aa) |
| | NJ7G_3395 | Propanoyl-CoA C-acyltransferase. (385 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (430 aa) |
| | NJ7G_3435 | Pyridoxal-5'-phosphate-dependent protein beta subunit. (327 aa) |
| | mat | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (401 aa) |
| | hemA-2 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (433 aa) |
| | NJ7G_3461 | Radical SAM domain protein. (406 aa) |
| | NJ7G_3493 | Fumarate reductase/succinate dehydrogenase flavoprotein domain protein. (626 aa) |
| | katG | Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (712 aa) |
| | NJ7G_3504 | Succinate dehydrogenase, cytochrome b556 subunit. (143 aa) |
| | NJ7G_3505 | Succinate dehydrogenase, subunit D. (121 aa) |
| | NJ7G_3506 | Succinate dehydrogenase and fumarate reductase iron-sulfur protein. (290 aa) |
| | NJ7G_3507 | Succinate dehydrogenase or fumarate reductase, flavoprotein subunit. (612 aa) |
| | NJ7G_3514 | acyl-CoA dehydrogenase domain-containing protein. (413 aa) |
| | NJ7G_3547 | acetate/CoA ligase. (659 aa) |
| | NJ7G_3549 | acetate/CoA ligase. (666 aa) |
| | NJ7G_3571 | Short-chain dehydrogenase/reductase SDR. (260 aa) |
| | NJ7G_3582 | Magnesium chelatase. (742 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (383 aa) |
| | NJ7G_3606 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (634 aa) |
| | NJ7G_3607 | Pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit. (311 aa) |
| | NJ7G_3629 | Nucleotidyl transferase. (465 aa) |
| | fbp | Inositol phosphatase/fructose-16-bisphosphatase. (289 aa) |
| | NJ7G_3648 | Fructose-bisphosphate aldolase. (264 aa) |
| | NJ7G_3653 | Squalene/phytoene synthase. (348 aa) |
| | ctaB-2 | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (473 aa) |
| | NJ7G_3667 | Propanoyl-CoA C-acyltransferase. (388 aa) |
| | NJ7G_3742 | Aminotransferase class I and II. (381 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (144 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (413 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (212 aa) |
| | surE-2 | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (273 aa) |
| | NJ7G_3764 | Prephenate dehydrogenase. (259 aa) |
| | NJ7G_3779 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (780 aa) |
| | NJ7G_3794 | AMP-dependent synthetase and ligase. (691 aa) |
| | NJ7G_3849 | Glycosyltransferase. (346 aa) |
| | gpmI | Phosphoglycerate mutase, 2,3-bisphosphoglycerate- independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (506 aa) |
| | NJ7G_3917 | Putative dTDP-glucose pyrophosphorylase. (357 aa) |
| | NJ7G_3918 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (181 aa) |
| | NJ7G_3920 | dTDP-4-dehydrorhamnose reductase. (303 aa) |
| | purC | SAICAR synthetase. (339 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (225 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (83 aa) |
| | NJ7G_4038 | Hydroxypyruvate reductase. (447 aa) |
| | NJ7G_4041 | Phosphoribosylglycinamide formyltransferase. (544 aa) |
| | NJ7G_4042 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (461 aa) |
| | NJ7G_4045 | Peptidase M20. (397 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine. (276 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (462 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (255 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (308 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (269 aa) |
| | NJ7G_4083 | Para-aminobenzoate synthase component I. (518 aa) |
| | NJ7G_4084 | Glutamine amidotransferase of anthranilate synthase. (229 aa) |
| | NJ7G_4092 | Aminotransferase class IV. (311 aa) |
| | NJ7G_4096 | Nucleotidyl transferase. (301 aa) |
| | trpC | Indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (278 aa) |
| | trpB-2 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (439 aa) |
| | trpA | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (301 aa) |
| | aroA-2 | Putative phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (264 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. (421 aa) |
| | aroD | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (224 aa) |
| | mfnA | Tyrosine decarboxylase; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily. (361 aa) |
| | NJ7G_4196 | Pyruvate kinase; Belongs to the pyruvate kinase family. (585 aa) |
| | NJ7G_4208 | Isocitrate dehydrogenase, NADP-dependent. (436 aa) |
| | NJ7G_4215 | 3-hydroxy-3-methylglutaryl Coenzyme A reductase; Belongs to the HMG-CoA reductase family. (408 aa) |
| | NJ7G_4277 | NAD-dependent epimerase/dehydratase; Catalyzes the NAD-dependent oxidation of glucose 6-phosphate to 6-phosphogluconolactone; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (257 aa) |
| | NJ7G_4348 | acyl-CoA dehydrogenase domain-containing protein. (433 aa) |
| | NJ7G_4371 | Short-chain dehydrogenase/reductase SDR. (261 aa) |
