STRINGSTRING
hpt hpt gpt gpt guaA guaA guaB guaB XNC1_3112 XNC1_3112
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
hptHypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (179 aa)
gptGuanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (153 aa)
guaAGMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. (525 aa)
guaBIMP dehydrogeanse; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (517 aa)
XNC1_3112Putative protein controls HAP (6-N-hydroxylaminopurine) mutagenesis (Ham1); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (199 aa)
Your Current Organism:
Xenorhabdus nematophila
NCBI taxonomy Id: 406817
Other names: X. nematophila ATCC 19061, Xenorhabdus nematophila ATCC 19061, Xenorhabdus nematophila str. ATCC 19061, Xenorhabdus nematophila strain ATCC 19061
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