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xcnK xcnK xcnA xcnA XNC1_1757 XNC1_1757 XNC1_1762 XNC1_1762 XNC1_1763 XNC1_1763 XNC1_2022 XNC1_2022 XNC1_2038 XNC1_2038 XNC1_0646 XNC1_0646 acs acs XNC1_1475 XNC1_1475 XNC1_2039 XNC1_2039 XNC1_2040 XNC1_2040 XNC1_2157 XNC1_2157 XNC1_2161 XNC1_2161 fadD fadD XNC1_2228 XNC1_2228 XNC1_2229 XNC1_2229 aas aas XNC1_1226 XNC1_1226 XNC1_1172 XNC1_1172 XNC1_2230 XNC1_2230 XNC1_2233 XNC1_2233 XNC1_2299 XNC1_2299 XNC1_2300 XNC1_2300 XNC1_2464 XNC1_2464 XNC1_2465 XNC1_2465 XNC1_2466 XNC1_2466 XNC1_2467 XNC1_2467 XNC1_2713 XNC1_2713 XNC1_2781 XNC1_2781 XNC1_2782 XNC1_2782 XNC1_2783 XNC1_2783 menE menE paaK paaK XNC1_1561 XNC1_1561 fliF fliF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
xcnKNon-ribosomal peptide synthase involved in xenocoumacin synthesis; Function experimentally demonstrated in the studied strain; enzyme. (857 aa)
xcnANon-ribosomal peptide synthase involved in Xenocoumacin synthesis; Function experimentally demonstrated in the studied strain; enzyme. (2672 aa)
XNC1_1757Putative Phenylalanine racemase (ATP-hydrolyzing). (4823 aa)
XNC1_1762Putative Phenylalanine racemase (ATP-hydrolyzing); Belongs to the ATP-dependent AMP-binding enzyme family. (2302 aa)
XNC1_1763Putative Phenylalanine racemase (ATP-hydrolyzing). (2396 aa)
XNC1_2022Non Ribosomal peptide synthetase (-succinylbenzoate--CoA ligase); Function of strongly homologous gene; enzyme. (4138 aa)
XNC1_2038Non-ribosomal peptide synthetase; Function of strongly homologous gene; enzyme. (5994 aa)
XNC1_0646Putative non-ribosomal peptide synthetase (fragment). (1054 aa)
acsacetyl-CoA synthetase, has propionyl-CoA synthetase activity; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compo [...] (651 aa)
XNC1_1475Non-ribosomal peptide synthetase; Function of strongly homologous gene; enzyme. (734 aa)
XNC1_2039Non-ribosomal peptide synthetase (fragment); Belongs to the ATP-dependent AMP-binding enzyme family. (2242 aa)
XNC1_2040Putative Phenylalanine racemase (ATP-hydrolyzing). (5480 aa)
XNC1_2157Phenylalanine racemase (ATP-hydrolyzing)(polyketide synthase); Function of strongly homologous gene; enzyme. (1893 aa)
XNC1_2161Putative Phenylalanine racemase (ATP-hydrolyzing). (1102 aa)
fadDacyl-CoA synthetase (long-chain-fatty-acid--CoA ligase). (563 aa)
XNC1_2228Peptide synthetase; Function of strongly homologous gene; enzyme. (1560 aa)
XNC1_2229Peptide synthetase; Function of strongly homologous gene; enzyme. (1554 aa)
aasBifunctional: 2-acylglycerophospho-ethanolamine acyl transferase (N-terminal); Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family. (717 aa)
XNC1_1226Putative acetyl-CoA synthetase of the propionate catabolism operon with firefly luciferase-like ATPase domain (fragment). (132 aa)
XNC1_1172Putative AMP-dependent synthetase/ligase. (535 aa)
XNC1_2230Peptide synthetase; Function of strongly homologous gene; enzyme. (1998 aa)
XNC1_2233Peptide synthetase (Phenylalanine racemase); Function of strongly homologous gene; enzyme; Belongs to the ATP-dependent AMP-binding enzyme family. (1403 aa)
XNC1_2299Putative Peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (2000 aa)
XNC1_2300Putative Peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1347 aa)
XNC1_2464Putative Phenylalanine racemase (ATP-hydrolyzing). (3642 aa)
XNC1_2465Conserved hypothetical protein; Belongs to the ATP-dependent AMP-binding enzyme family. (1138 aa)
XNC1_2466Putative Ornithine racemase. (3279 aa)
XNC1_2467Putative Ornithine racemase. (2773 aa)
XNC1_2713Putative Non-ribosomal peptide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (4949 aa)
XNC1_2781Peptide synthetase XpsB. (3592 aa)
XNC1_2782Peptide synthetase XpsB. (3326 aa)
XNC1_2783Peptide synthetase XpsA; Belongs to the ATP-dependent AMP-binding enzyme family. (1079 aa)
menEo-succinylbenzoate-CoA ligase. (467 aa)
paaKphenylacetyl-CoA ligase, phenylacetic acid degradation; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (447 aa)
XNC1_1561Putative Nonribosomal peptide synthase (NRPS); Belongs to the ATP-dependent AMP-binding enzyme family. (1019 aa)
fliFFlagellar biosynthesis; The M ring may be actively involved in energy transduction. Belongs to the FliF family. (574 aa)
Your Current Organism:
Xenorhabdus nematophila
NCBI taxonomy Id: 406817
Other names: X. nematophila ATCC 19061, Xenorhabdus nematophila ATCC 19061, Xenorhabdus nematophila str. ATCC 19061, Xenorhabdus nematophila strain ATCC 19061
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