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sthA sthA gabD gabD nudC nudC nadR nadR gabD-2 gabD-2 XNC1_0881 XNC1_0881 ushA ushA XNC1_1260 XNC1_1260 nadD nadD pncB pncB pntA pntA pntB pntB pncA pncA cobB cobB nadK nadK nadE nadE rihB rihB deoD deoD surE surE
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Your Input:
sthASoluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (465 aa)
gabDSuccinate-semialdehyde dehydrogenase I, NADP-dependent; Belongs to the aldehyde dehydrogenase family. (477 aa)
nudCNADH pyrophosphatase; Belongs to the Nudix hydrolase family. NudC subfamily. (257 aa)
nadRTranscriptional regulator of NAD biosynthesis; regulator of PnuC activity; NMN adenylyltransferase. (408 aa)
gabD-2Succinate-semialdehyde dehydrogenase I, NADP-dependent; Belongs to the aldehyde dehydrogenase family. (490 aa)
XNC1_0881Protein mazG. (266 aa)
ushABifunctional: UDP-sugar hydrolase; 5'-nucleotidase; Belongs to the 5'-nucleotidase family. (552 aa)
XNC1_1260Conserved hypothetical protein; Belongs to the CinA family. (167 aa)
nadDNicotinic acid mononucleotide adenylyltransferase, NAD(P)-requiring; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (246 aa)
pncBNicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (404 aa)
pntAPyridine nucleotide transhydrogenase (proton pump), alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. (510 aa)
pntBPyridine nucleotide transhydrogenase (proton pump), beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (462 aa)
pncANicotinamidase/pyrazinamidase. (222 aa)
cobBPutative enzyme with DHS-like NAD/FAD-binding domain; Belongs to the sirtuin family. Class III subfamily. (276 aa)
nadKNAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (299 aa)
nadEPutative glutamine-dependent NAD(+) synthetase (NAD(+) synthase [glutamine-hydrolyzing]) (NadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (540 aa)
rihBRibonucleoside hydrolase 2, pyrimidine-specific, silent; Belongs to the IUNH family. (316 aa)
deoDPurine-nucleoside phosphorylase. (238 aa)
surESurvival protein, protein damage control; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. (254 aa)
Your Current Organism:
Xenorhabdus nematophila
NCBI taxonomy Id: 406817
Other names: X. nematophila ATCC 19061, Xenorhabdus nematophila ATCC 19061, Xenorhabdus nematophila str. ATCC 19061, Xenorhabdus nematophila strain ATCC 19061
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