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pfp pfp THII_0786 THII_0786 THII_0913 THII_0913 pgi pgi THII_1549 THII_1549 THII_3338 THII_3338 THII_3339 THII_3339 pgk pgk tpiA tpiA THII_3498 THII_3498 THII_3499 THII_3499 eno eno THII_3702 THII_3702 THII_3736 THII_3736 gpmA gpmA glk glk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (422 aa)
THII_0786Hypothetical protein. (438 aa)
THII_0913Formate hydrogenlyase. (226 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (550 aa)
THII_1549Formate hydrogenlyase subunit 4. (330 aa)
THII_3338Ketose-bisphosphate aldolase, class-II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (353 aa)
THII_3339Pyruvate kinase; Belongs to the pyruvate kinase family. (480 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (394 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
THII_3498Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (454 aa)
THII_3499Pyruvate dehydrogenase E1 component, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (886 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (427 aa)
THII_3702Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (223 aa)
THII_3736Phosphoglycerate/bisphosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (210 aa)
gpmAPhosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (248 aa)
glkGlucokinase; Belongs to the bacterial glucokinase family. (342 aa)
Your Current Organism:
Thioploca ingrica
NCBI taxonomy Id: 40754
Other names: T. ingrica
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