(29 nodes) Side of membrane network (Thioploca ingrica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	THII_3263	Anaerobic dehydrogenase-like component. (258 aa)
	THII_3280	Septum site-determining protein MinD. (268 aa)
	THII_3365	Hypothetical protein. (286 aa)
	THII_2775	Band 7 protein. (236 aa)
	lapB	Heat shock protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. (395 aa)
	THII_0024	Molecular chaperone TorD. (171 aa)
	rne	Ribonuclease, Rne/Rng family; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (694 aa)
	hflD	Uncharacterized protein involved in purine metabolism. (208 aa)
	ftsA	Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (411 aa)
	THII_2510	Membrane protease subunit, stomatin/prohibitin. (398 aa)
	THII_2393	Band 7 protein; HflC and HflK could regulate a protease. (328 aa)
	hypA	Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (114 aa)
	THII_2196	Transposase, IS4 family. (292 aa)
	THII_3870	Ribonuclease G and E. (525 aa)
	THII_3950	Phage shock protein A (IM30), suppresses sigma54-dependent transcription. (225 aa)
	THII_3234	Cobyrinic acid a,c-diamide synthase. (348 aa)
	THII_3172	Hypothetical protein. (917 aa)
	THII_2195	Transposase, IS4 family. (141 aa)
	ccmE	Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (160 aa)
	THII_2861	Hypothetical protein. (966 aa)
	THII_1355	Hypothetical protein. (104 aa)
	ftsE	Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (223 aa)
	lgt	Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (261 aa)
	ccmA	Cytochrome c biogenesis protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (220 aa)
	THII_0143	Parvulin-like peptidyl-prolyl isomerase. (647 aa)
	THII_2989	Glycoside hydrolase family protein. (124 aa)
	THII_2919	Hypothetical protein. (250 aa)
	THII_3251	Cytochrome c biogenesis protein; Possible subunit of a heme lyase. (153 aa)
	THII_3252	TPR repeat containing protein. (425 aa)

Your Current Organism:

Thioploca ingrica

NCBI taxonomy Id: 40754
Other names: T. ingrica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
THII_0143	THII_3365	THII_0143	THII_3365	Parvulin-like peptidyl-prolyl isomerase.	Hypothetical protein.	0.458
THII_2195	THII_2196	THII_2195	THII_2196	Transposase, IS4 family.	Transposase, IS4 family.	0.974
THII_2196	THII_2195	THII_2196	THII_2195	Transposase, IS4 family.	Transposase, IS4 family.	0.974
THII_3251	THII_3252	THII_3251	THII_3252	Cytochrome c biogenesis protein; Possible subunit of a heme lyase.	TPR repeat containing protein.	0.989
THII_3251	ccmA	THII_3251	THII_0662	Cytochrome c biogenesis protein; Possible subunit of a heme lyase.	Cytochrome c biogenesis protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	0.841
THII_3251	ccmE	THII_3251	THII_3166	Cytochrome c biogenesis protein; Possible subunit of a heme lyase.	Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.	0.865
THII_3252	THII_3251	THII_3252	THII_3251	TPR repeat containing protein.	Cytochrome c biogenesis protein; Possible subunit of a heme lyase.	0.989
THII_3252	ccmA	THII_3252	THII_0662	TPR repeat containing protein.	Cytochrome c biogenesis protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	0.818
THII_3252	ccmE	THII_3252	THII_3166	TPR repeat containing protein.	Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.	0.844
THII_3365	THII_0143	THII_3365	THII_0143	Hypothetical protein.	Parvulin-like peptidyl-prolyl isomerase.	0.458
THII_3365	lapB	THII_3365	THII_0037	Hypothetical protein.	Heat shock protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.	0.481
ccmA	THII_3251	THII_0662	THII_3251	Cytochrome c biogenesis protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	Cytochrome c biogenesis protein; Possible subunit of a heme lyase.	0.841
ccmA	THII_3252	THII_0662	THII_3252	Cytochrome c biogenesis protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	TPR repeat containing protein.	0.818
ccmA	ccmE	THII_0662	THII_3166	Cytochrome c biogenesis protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.	0.883
ccmE	THII_3251	THII_3166	THII_3251	Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.	Cytochrome c biogenesis protein; Possible subunit of a heme lyase.	0.865
ccmE	THII_3252	THII_3166	THII_3252	Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.	TPR repeat containing protein.	0.844
ccmE	ccmA	THII_3166	THII_0662	Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.	Cytochrome c biogenesis protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.	0.883
lapB	THII_3365	THII_0037	THII_3365	Heat shock protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.	Hypothetical protein.	0.481