(46 nodes) Porphyrin and chlorophyll metabolism network (Solanum lycopersicum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	A0A3Q7EGF4	NAD(P)-bd_dom domain-containing protein. (420 aa)
	A0A3Q7EHA7	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (451 aa)
	A0A3Q7EIN5	TP_methylase domain-containing protein; Belongs to the precorrin methyltransferase family. (376 aa)
	A0A3Q7ERP6	Glutamyl-tRNA reductase; Belongs to the glutamyl-tRNA reductase family. (552 aa)
	A0A3Q7F889	CbiX domain-containing protein. (206 aa)
	A0A3Q7FCW5	Uncharacterized protein. (718 aa)
	A0A3Q7FEP9	Uncharacterized protein. (1102 aa)
	A0A3Q7FGN1	Uncharacterized protein. (314 aa)
	A0A3Q7FHT9	RING-type domain-containing protein. (105 aa)
	A0A3Q7FUB1	Mg-por_mtran_C domain-containing protein. (396 aa)
	A0A3Q7FY87	Mg-protoporphyrin IX chelatase; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. Belongs to the Mg-chelatase subunits D/I family. (766 aa)
	GSA-AT	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (482 aa)
	A0A3Q7G0W1	DUF3479 domain-containing protein. (1381 aa)
	A0A3Q7G340	Staygreen domain-containing protein. (242 aa)
	A0A3Q7G876	Glutamyl-tRNA reductase; Belongs to the glutamyl-tRNA reductase family. (544 aa)
	A0A3Q7GF00	Uncharacterized protein; Belongs to the ferrochelatase family. (162 aa)
	A0A3Q7GJR4	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (317 aa)
	A0A3Q7GR78	Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (388 aa)
	A0A3Q7GUQ9	Rieske domain-containing protein. (535 aa)
	A0A3Q7H105	Uncharacterized protein. (750 aa)
	A0A3Q7H4I4	TPR_REGION domain-containing protein. (551 aa)
	A0A3Q7H6Q7	Uncharacterized protein. (484 aa)
	A0A3Q7HCM1	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (346 aa)
	POR2	NADPH-protochlorophyllide oxidoreductase; Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide); Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily. (399 aa)
	A0A3Q7HGD7	Uncharacterized protein. (365 aa)
	A0A3Q7HMZ6	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (489 aa)
	A0A3Q7HN24	Uncharacterized protein; Belongs to the ferrochelatase family. (447 aa)
	A0A3Q7HPJ9	Uncharacterized protein. (312 aa)
	A0A3Q7I124	Uncharacterized protein. (369 aa)
	A0A3Q7I3Z4	Uncharacterized protein. (307 aa)
	A0A3Q7I6E4	Uncharacterized protein. (309 aa)
	A0A3Q7I822	Uncharacterized protein. (459 aa)
	A0A3Q7I9A2	Uncharacterized protein. (399 aa)
	A0A3Q7IBI0	NADPH-protochlorophyllide oxidoreductase; Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide); Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily. (395 aa)
	A0A3Q7IBR0	Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (420 aa)
	A0A3Q7IJM9	Uncharacterized protein; Belongs to the ferrochelatase family. (128 aa)
	A0A3Q7IJU8	Rubrerythrin domain-containing protein. (404 aa)
	A0A3Q7ILF6	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (454 aa)
	A0A3Q7IMI0	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (488 aa)
	A0A3Q7IS91	Rieske domain-containing protein. (535 aa)
	A0A3Q7J1P1	Uncharacterized protein. (340 aa)
	A0A3Q7J565	NADPH-protochlorophyllide oxidoreductase; Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide); Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily. (397 aa)
	A0A3Q7J6X7	Mg-protoporphyrin IX chelatase; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. Belongs to the Mg-chelatase subunits D/I family. (427 aa)
	A0A3Q7JB25	Staygreen domain-containing protein. (247 aa)
	A0A3Q7JNY6	Rieske domain-containing protein. (537 aa)
	SGR1	Protein STAY-GREEN 1, chloroplastic; Required to trigger chlorophyll degradation during leaf senescence and fruit ripening (Ref.3,. Binds directly PSY1 to regulate the accumulation of lycopene and beta-carotene in the maturing fruits. Belongs to the staygreen family. (272 aa)

Your Current Organism:

Solanum lycopersicum

NCBI taxonomy Id: 4081
Other names: Lycopersicon esculentum, Lycopersicon esculentum Mill., Lycopersicon esculentum var. esculentum, S. lycopersicum, Solanum esculentum, Solanum esculentum Dunal, Solanum lycopersicum L., Solanum lycopersicum var. humboldtii, tomato

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A3Q7EGF4	A0A3Q7EHA7	A0A3Q7EGF4	A0A3Q7EHA7	NAD(P)-bd_dom domain-containing protein.	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.	0.524
A0A3Q7EGF4	A0A3Q7ERP6	A0A3Q7EGF4	A0A3Q7ERP6	NAD(P)-bd_dom domain-containing protein.	Glutamyl-tRNA reductase; Belongs to the glutamyl-tRNA reductase family.	0.876
A0A3Q7EGF4	A0A3Q7FEP9	A0A3Q7EGF4	A0A3Q7FEP9	NAD(P)-bd_dom domain-containing protein.	Uncharacterized protein.	0.526
A0A3Q7EGF4	A0A3Q7FGN1	A0A3Q7EGF4	A0A3Q7FGN1	NAD(P)-bd_dom domain-containing protein.	Uncharacterized protein.	0.493
A0A3Q7EGF4	A0A3Q7FUB1	A0A3Q7EGF4	A0A3Q7FUB1	NAD(P)-bd_dom domain-containing protein.	Mg-por_mtran_C domain-containing protein.	0.692
A0A3Q7EGF4	A0A3Q7FY87	A0A3Q7EGF4	A0A3Q7FY87	NAD(P)-bd_dom domain-containing protein.	Mg-protoporphyrin IX chelatase; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. Belongs to the Mg-chelatase subunits D/I family.	0.889
A0A3Q7EGF4	A0A3Q7G0W1	A0A3Q7EGF4	A0A3Q7G0W1	NAD(P)-bd_dom domain-containing protein.	DUF3479 domain-containing protein.	0.642
A0A3Q7EGF4	A0A3Q7G340	A0A3Q7EGF4	A0A3Q7G340	NAD(P)-bd_dom domain-containing protein.	Staygreen domain-containing protein.	0.900
A0A3Q7EGF4	A0A3Q7G876	A0A3Q7EGF4	A0A3Q7G876	NAD(P)-bd_dom domain-containing protein.	Glutamyl-tRNA reductase; Belongs to the glutamyl-tRNA reductase family.	0.833
A0A3Q7EGF4	A0A3Q7GR78	A0A3Q7EGF4	A0A3Q7GR78	NAD(P)-bd_dom domain-containing protein.	Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.	0.573
A0A3Q7EGF4	A0A3Q7GUQ9	A0A3Q7EGF4	A0A3Q7GUQ9	NAD(P)-bd_dom domain-containing protein.	Rieske domain-containing protein.	0.965
A0A3Q7EGF4	A0A3Q7H6Q7	A0A3Q7EGF4	A0A3Q7H6Q7	NAD(P)-bd_dom domain-containing protein.	Uncharacterized protein.	0.583
A0A3Q7EGF4	A0A3Q7HCM1	A0A3Q7EGF4	A0A3Q7HCM1	NAD(P)-bd_dom domain-containing protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.571
A0A3Q7EGF4	A0A3Q7HGD7	A0A3Q7EGF4	A0A3Q7HGD7	NAD(P)-bd_dom domain-containing protein.	Uncharacterized protein.	0.593
A0A3Q7EGF4	A0A3Q7HPJ9	A0A3Q7EGF4	A0A3Q7HPJ9	NAD(P)-bd_dom domain-containing protein.	Uncharacterized protein.	0.900
A0A3Q7EGF4	A0A3Q7I124	A0A3Q7EGF4	A0A3Q7I124	NAD(P)-bd_dom domain-containing protein.	Uncharacterized protein.	0.973
A0A3Q7EGF4	A0A3Q7I3Z4	A0A3Q7EGF4	A0A3Q7I3Z4	NAD(P)-bd_dom domain-containing protein.	Uncharacterized protein.	0.900
A0A3Q7EGF4	A0A3Q7I6E4	A0A3Q7EGF4	A0A3Q7I6E4	NAD(P)-bd_dom domain-containing protein.	Uncharacterized protein.	0.900
A0A3Q7EGF4	A0A3Q7I822	A0A3Q7EGF4	A0A3Q7I822	NAD(P)-bd_dom domain-containing protein.	Uncharacterized protein.	0.566
A0A3Q7EGF4	A0A3Q7I9A2	A0A3Q7EGF4	A0A3Q7I9A2	NAD(P)-bd_dom domain-containing protein.	Uncharacterized protein.	0.530

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