STRINGSTRING
LoxF LoxF TomloxE TomloxE A0A3Q7EN25 A0A3Q7EN25 A0A3Q7ENA3 A0A3Q7ENA3 A0A3Q7ENA4 A0A3Q7ENA4 Opr2 Opr2 TomloxC TomloxC A0A3Q7EUJ3 A0A3Q7EUJ3 A0A3Q7F8D0 A0A3Q7F8D0 A0A3Q7FW38 A0A3Q7FW38 LoxD LoxD A0A3Q7GDK8 A0A3Q7GDK8 A0A3Q7HN01 A0A3Q7HN01 A0A3Q7I7A9 A0A3Q7I7A9 A0A3Q7IQ54 A0A3Q7IQ54 A0A3Q7IV99 A0A3Q7IV99 A0A3Q7IXS9 A0A3Q7IXS9 A0A3Q7JD55 A0A3Q7JD55 A0A3Q7JSV3 A0A3Q7JSV3 AOS1 AOS1 HPL HPL alpha-DOX2 alpha-DOX2 AOS3 AOS3 OPR3 OPR3 aoc aoc AOS2 AOS2 OPR1 OPR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LoxFLipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (447 aa)
TomloxELipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (1520 aa)
A0A3Q7EN25Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (1634 aa)
A0A3Q7ENA3Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (859 aa)
A0A3Q7ENA4Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (854 aa)
Opr2Oxidored_FMN domain-containing protein. (355 aa)
TomloxCUncharacterized protein. (557 aa)
A0A3Q7EUJ3Uncharacterized protein; Belongs to the cytochrome P450 family. (938 aa)
A0A3Q7F8D0Uncharacterized protein. (632 aa)
A0A3Q7FW38Uncharacterized protein. (412 aa)
LoxDLipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (908 aa)
A0A3Q7GDK8Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (911 aa)
A0A3Q7HN01Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (861 aa)
A0A3Q7I7A9Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (1731 aa)
A0A3Q7IQ54Uncharacterized protein. (565 aa)
A0A3Q7IV99Oxidored_FMN domain-containing protein. (354 aa)
A0A3Q7IXS9Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (510 aa)
A0A3Q7JD55Uncharacterized protein. (552 aa)
A0A3Q7JSV3Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (538 aa)
AOS1Allene oxide synthase 1, chloroplastic; Cytochrome P450 of the CYP74A subfamily involved in the biosynthesis of jasmonic acid from lipoxygenase-derived hydroperoxides of free fatty acids. Catalyzes the synthesis of unstable allene oxide, which is further converted spontaneously by hydrolysis or cyclization. Can use 13S-hydroperoxy-9(Z),11(E),15(Z)-octadecatrienoic acid (13- HPOT) and 13S-hydroperoxy-9(Z),11(E)-octadecadienoic acid (13-HPOD) as substrates. (534 aa)
HPLFatty acid hydroperoxide lyase, chloroplastic; Cytochrome P450 of the CYP74B subfamily involved in the biosynthesis of traumatin and C6 aldehydes. Metabolizes 13- but not 9-hydroperoxides of linoleic and linolenic acids. Can use 15S- hydroperoxy-11(Z),13(E),17(Z)-eicosatrienoic acid (15-HPET) and 13S- hydroperoxy-9(Z),11(E),15(Z)-octadecatrienoic acid (13-HPOT) as substrates, but only 5% activity with 13S-hydroperoxy-9(Z),11(E)- octadecadienoic acid (13-HPOD). Produces n-hexanal and 12-oxo-9(Z)-dodecanoic acid from 13-HPOD. (476 aa)
alpha-DOX2Alpha-dioxygenase 2 enzyme. (632 aa)
AOS3Allene oxide synthase 3; Cytochrome P450 metabolizing both 13- and 9-hydroperoxides of linoleic and linolenic acids, but with a marked preference for 9- hydroperoxy fatty acids. Has no activity toward 13S-hydroperoxy-9(Z),11(E),15(Z)-octadecatrienoic acid (13-HPOT). Catalyzes not only the synthesis of allene oxide, but also its hydrolysis and cyclization. The first step is the synthesis of (12Z)-9,10-epoxyoctadeca-10,12-dienoic acid (9,10-EOD) and the final products are (9R)-alpha-ketol and the racemic cis-10-oxo-11-phytoenoic acid. The cyclase activity possesses regiospecificity and ( [...] (491 aa)
OPR312-oxophytodienoate reductase 3; Specifically cleaves olefinic bonds in cyclic enones. Involved in the biosynthesis of jasmonic acid (JA) and perhaps in biosynthesis or metabolism of other oxylipin signaling moleclules. It is required for the spatial and temporal regulation of JA levels during dehiscence of anthers, promoting the stomium degeneration program (By similarity). In vitro, reduces 9S,13S-12-oxophytodienoic acid (9S,13S- OPDA) and 9R,13R-OPDA to 9S,13S-OPC-8:0 and 9R,13R-OPC-8:0, respectively; Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. (396 aa)
aocAllene oxide cyclase. (244 aa)
AOS2Allene oxide synthase 2, chloroplastic; Cytochrome P450 of the CYP74A subfamily involved in the biosynthesis of jasmonic acid from lipoxygenase-derived hydroperoxides of free fatty acids. Catalyzes the synthesis of unstable allene oxide, which is further converted spontaneously by hydrolysis or cyclization. Metabolizes 13- but not 9-hydroperoxides of linoleic and linolenic acids. Can use 15S-hydroperoxy-11(Z),13(E),17(Z)-eicosatrienoic acid (15-HPET) and 13S-hydroperoxy-9(Z),11(E),15(Z)-octadecatrienoic acid (13-HPOT) as substrates, but only 50% activity with 13S-hydroperoxy- 9(Z),11(E [...] (510 aa)
OPR112-oxophytodienoate reductase 1; Specifically cleaves olefinic bonds in alpha,beta-unsaturated carbonyls and may be involved in detoxification or modification of these reactive compounds. May be involved in the biosynthesis or metabolism of oxylipin signaling molecules. In vitro, reduces 9R,13R- 12-oxophyodienoic acid (9R,13R-OPDA) to 9R,13R-OPC-8:0, but not 9S,13S- OPDA, the natural precursor of jasmonic acid. Also reduces N- ethylmaleimide and maleic acid; Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. (376 aa)
Your Current Organism:
Solanum lycopersicum
NCBI taxonomy Id: 4081
Other names: Lycopersicon esculentum, Lycopersicon esculentum Mill., Lycopersicon esculentum var. esculentum, S. lycopersicum, Solanum esculentum, Solanum esculentum Dunal, Solanum lycopersicum L., Solanum lycopersicum var. humboldtii, tomato
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