(84 nodes) Flavonoid biosynthesis, and AMP-binding enzyme, C-terminal domain network (Solanum lycopersicum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A3Q7E8S4	Uncharacterized protein. (274 aa)
	A0A3Q7EAD4	Uncharacterized protein; Belongs to the cytochrome P450 family. (507 aa)
	A0A3Q7ESA3	Uncharacterized protein. (257 aa)
	A0A3Q7F0V5	Hydrolase_4 domain-containing protein. (373 aa)
	A0A3Q7F5L4	Uncharacterized protein. (437 aa)
	A0A3Q7F5S6	Uncharacterized protein. (440 aa)
	F3H	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (362 aa)
	A0A3Q7F7T4	Uncharacterized protein. (438 aa)
	A0A3Q7FDU8	Uncharacterized protein. (242 aa)
	A0A3Q7FDV2	Uncharacterized protein. (304 aa)
	A0A3Q7FFN0	Uncharacterized protein. (234 aa)
	A0A3Q7FGA3	Phenylalanine ammonia-lyase. (484 aa)
	A0A3Q7FHW6	Epimerase domain-containing protein. (334 aa)
	A0A3Q7FRD3	Uncharacterized protein. (552 aa)
	A0A3Q7FTB8	Uncharacterized protein. (435 aa)
	A0A3Q7FTN2	X8 domain-containing protein. (749 aa)
	A0A3Q7FUU7	Hydrolase_4 domain-containing protein. (327 aa)
	A0A3Q7FX33	Uncharacterized protein. (1142 aa)
	A0A3Q7GBK5	NmrA domain-containing protein. (76 aa)
	CHI1	Chalcone-flavonone isomerase family protein; Belongs to the chalcone isomerase family. (204 aa)
	A0A3Q7GCJ0	Uncharacterized protein. (570 aa)
	A0A3Q7GDH4	Hydrolase_4 domain-containing protein. (397 aa)
	A0A3Q7GF23	Chalcone-flavonone isomerase family protein; Belongs to the chalcone isomerase family. (222 aa)
	A0A3Q7GFM3	Uncharacterized protein. (431 aa)
	4CL	Uncharacterized protein. (699 aa)
	A0A3Q7GIN5	Uncharacterized protein. (146 aa)
	A0A3Q7GLK0	Uncharacterized protein. (121 aa)
	CHS2-2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. (389 aa)
	A0A3Q7GPF4	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. (361 aa)
	A0A3Q7GQI7	Hydrolase_4 domain-containing protein. (319 aa)
	A0A3Q7H037	Uncharacterized protein. (560 aa)
	A0A3Q7H4X1	Methyltransf_2 domain-containing protein. (230 aa)
	A0A3Q7H4X3	Uncharacterized protein. (774 aa)
	A0A3Q7H6N0	Uncharacterized protein. (450 aa)
	A0A3Q7H6Z8	Uncharacterized protein. (461 aa)
	A0A3Q7H7I5	Uncharacterized protein. (445 aa)
	A0A3Q7H8S7	Uncharacterized protein. (451 aa)
	A0A3Q7HCX3	Uncharacterized protein. (419 aa)
	A0A3Q7HE34	Uncharacterized protein; Belongs to the cytochrome P450 family. (528 aa)
	A0A3Q7HFP3	Chalcone-flavonone isomerase family protein; Belongs to the chalcone isomerase family. (209 aa)
	A0A3Q7HG80	Uncharacterized protein; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. (392 aa)
	A0A3Q7HJ18	Uncharacterized protein. (436 aa)
	A0A3Q7HTA5	Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
	A0A3Q7HTJ6	Uncharacterized protein. (957 aa)
	A0A3Q7HVK9	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (436 aa)
	A0A3Q7HXX4	Uncharacterized protein. (317 aa)
	A0A3Q7HYF0	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. (361 aa)
	A0A3Q7I071	Uncharacterized protein. (452 aa)
	A0A3Q7I495	Glycosyltransferase; Belongs to the UDP-glycosyltransferase family. (469 aa)
	A0A3Q7ID95	Uncharacterized protein; Belongs to the PAL/histidase family. (1391 aa)
	A0A3Q7IDJ3	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (356 aa)
	A0A3Q7IGY7	Uncharacterized protein. (245 aa)
	A0A3Q7IJA9	Uncharacterized protein; Belongs to the cytochrome P450 family. (340 aa)
	A0A3Q7IPA2	Phenylalanine ammonia-lyase. (711 aa)
	A0A3Q7IQR1	Uncharacterized protein. (461 aa)
	A0A3Q7IZ99	Uncharacterized protein. (439 aa)
	A0A3Q7IZP9	Uncharacterized protein. (1395 aa)
	A0A3Q7IZU3	Uncharacterized protein. (538 aa)
	A0A3Q7J0W2	Uncharacterized protein. (443 aa)
	A0A3Q7J189	Uncharacterized protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (965 aa)
	A0A3Q7J1E2	Uncharacterized protein. (443 aa)
	A0A3Q7J1H6	Hydrolase_4 domain-containing protein. (352 aa)
	A0A3Q7J2A9	Uncharacterized protein. (439 aa)
	CHS1-2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. (389 aa)
	A0A3Q7J4U7	Uncharacterized protein. (464 aa)
	A0A3Q7J8S1	Uncharacterized protein. (548 aa)
	A0A3Q7JJW7	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (352 aa)
	A0A3Q7JQD0	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (359 aa)
	A0A3Q7JRL8	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (500 aa)
	A0A3Q7JYN3	Uncharacterized protein. (459 aa)
	B5M6H1_SOLLC	Anthocyanin acyltransferase. (454 aa)
	AT3	AT3. (454 aa)
	AT1	AT1. (452 aa)
	K4BPC3_SOLLC	Uncharacterized protein. (220 aa)
	K4C0B3_SOLLC	Uncharacterized protein. (154 aa)
	K4C0H5_SOLLC	Uncharacterized protein. (47 aa)
	HQT	Hydroxycinnamoyl-CoA:quinate hydroxycinnamoyl transferase. (430 aa)
	AnthOMT	Anthocyanin O-methyltransferase. (235 aa)
	K4D2J5_SOLLC	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. (355 aa)
	CHS2	Chalcone synthase 2; The primary product of this enzyme is 4,2',4',6'- tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin. (389 aa)
	PAL	Phenylalanine ammonia-lyase; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton; Belongs to the PAL/histidase family. (704 aa)
	DFRA_SOLLC	Dihydroflavonol 4-reductase; Bifunctional enzyme involved in flavonoid metabolism. (379 aa)
	CCR2	Cinnamoyl-CoA reductase. (332 aa)
	CCR1	Cinnamoyl-CoA reductase. (332 aa)

Your Current Organism:

Solanum lycopersicum

NCBI taxonomy Id: 4081
Other names: Lycopersicon esculentum, Lycopersicon esculentum Mill., Lycopersicon esculentum var. esculentum, S. lycopersicum, Solanum esculentum, Solanum esculentum Dunal, Solanum lycopersicum L., Solanum lycopersicum var. humboldtii, tomato

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
4CL	A0A3Q7E8S4	A0A3Q7GIB5	A0A3Q7E8S4	Uncharacterized protein.	Uncharacterized protein.	0.689
4CL	A0A3Q7EAD4	A0A3Q7GIB5	A0A3Q7EAD4	Uncharacterized protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.501
4CL	A0A3Q7ESA3	A0A3Q7GIB5	A0A3Q7ESA3	Uncharacterized protein.	Uncharacterized protein.	0.902
4CL	A0A3Q7F0V5	A0A3Q7GIB5	A0A3Q7F0V5	Uncharacterized protein.	Hydrolase_4 domain-containing protein.	0.848
4CL	A0A3Q7F5L4	A0A3Q7GIB5	A0A3Q7F5L4	Uncharacterized protein.	Uncharacterized protein.	0.689
4CL	A0A3Q7F5S6	A0A3Q7GIB5	A0A3Q7F5S6	Uncharacterized protein.	Uncharacterized protein.	0.689
4CL	A0A3Q7F7T4	A0A3Q7GIB5	A0A3Q7F7T4	Uncharacterized protein.	Uncharacterized protein.	0.689
4CL	A0A3Q7FDU8	A0A3Q7GIB5	A0A3Q7FDU8	Uncharacterized protein.	Uncharacterized protein.	0.902
4CL	A0A3Q7FDV2	A0A3Q7GIB5	A0A3Q7FDV2	Uncharacterized protein.	Uncharacterized protein.	0.902
4CL	A0A3Q7FFN0	A0A3Q7GIB5	A0A3Q7FFN0	Uncharacterized protein.	Uncharacterized protein.	0.897
4CL	A0A3Q7FGA3	A0A3Q7GIB5	A0A3Q7FGA3	Uncharacterized protein.	Phenylalanine ammonia-lyase.	0.883
4CL	A0A3Q7FHW6	A0A3Q7GIB5	A0A3Q7FHW6	Uncharacterized protein.	Epimerase domain-containing protein.	0.519
4CL	A0A3Q7FTB8	A0A3Q7GIB5	A0A3Q7FTB8	Uncharacterized protein.	Uncharacterized protein.	0.707
4CL	A0A3Q7FTN2	A0A3Q7GIB5	A0A3Q7FTN2	Uncharacterized protein.	X8 domain-containing protein.	0.592
4CL	A0A3Q7FUU7	A0A3Q7GIB5	A0A3Q7FUU7	Uncharacterized protein.	Hydrolase_4 domain-containing protein.	0.851
4CL	A0A3Q7GDH4	A0A3Q7GIB5	A0A3Q7GDH4	Uncharacterized protein.	Hydrolase_4 domain-containing protein.	0.847
4CL	A0A3Q7GFM3	A0A3Q7GIB5	A0A3Q7GFM3	Uncharacterized protein.	Uncharacterized protein.	0.689
4CL	A0A3Q7GIN5	A0A3Q7GIB5	A0A3Q7GIN5	Uncharacterized protein.	Uncharacterized protein.	0.897
4CL	A0A3Q7GLK0	A0A3Q7GIB5	A0A3Q7GLK0	Uncharacterized protein.	Uncharacterized protein.	0.897
4CL	A0A3Q7GPF4	A0A3Q7GIB5	A0A3Q7GPF4	Uncharacterized protein.	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.	0.872

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