(30 nodes) Brassinosteroid biosynthetic process network (Solanum lycopersicum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A3Q7IC09	Uncharacterized protein; Belongs to the cytochrome P450 family. (481 aa)
	SSR2	Sterol side chain reductase. (566 aa)
	A0A3Q7E9H9	Uncharacterized protein. (434 aa)
	A0A3Q7EII3	Uncharacterized protein; Belongs to the cytochrome P450 family. (497 aa)
	A0A3Q7EKQ0	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (324 aa)
	SlSSR1	FAD-binding PCMH-type domain-containing protein. (625 aa)
	A0A3Q7F7B3	Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
	A0A3Q7F9H0	Uncharacterized protein; Belongs to the cytochrome P450 family. (486 aa)
	A0A3Q7FE01	Uncharacterized protein; Belongs to the cytochrome P450 family. (400 aa)
	CYP90B3	Uncharacterized protein; Belongs to the cytochrome P450 family. (492 aa)
	A0A3Q7FVN9	Uncharacterized protein; Belongs to the cytochrome P450 family. (486 aa)
	A0A3Q7FZ48	Uncharacterized protein; Belongs to the cytochrome P450 family. (466 aa)
	A0A3Q7G393	Uncharacterized protein; Belongs to the cytochrome P450 family. (486 aa)
	A0A3Q7G6X6	Uncharacterized protein; Belongs to the cytochrome P450 family. (477 aa)
	A0A3Q7GBH0	Uncharacterized protein. (358 aa)
	A0A3Q7GIK0	Uncharacterized protein. (118 aa)
	A0A3Q7GN97	3Beta_HSD domain-containing protein. (164 aa)
	A0A3Q7H0B6	Uncharacterized protein. (434 aa)
	CYP724B2	Uncharacterized protein; Belongs to the cytochrome P450 family. (467 aa)
	A0A3Q7HI15	Uncharacterized protein. (216 aa)
	A0A3Q7HKZ1	Uncharacterized protein; Belongs to the cytochrome P450 family. (386 aa)
	A0A3Q7HVR6	Uncharacterized protein; Belongs to the cytochrome P450 family. (476 aa)
	A0A3Q7HY94	Uncharacterized protein. (131 aa)
	A0A3Q7ICT3	3Beta_HSD domain-containing protein. (251 aa)
	A0A3Q7IEG4	Uncharacterized protein; Belongs to the cytochrome P450 family. (496 aa)
	A0A3Q7J325	Uncharacterized protein; Belongs to the cytochrome P450 family. (487 aa)
	K4C5W4_SOLLC	CYP90A1-like protein; Belongs to the cytochrome P450 family. (487 aa)
	CYP85A1	Cytochrome P450 85A1; Catalyzes the C6-oxidation step in brassinosteroids biosynthesis. Converts 6-deoxocastasterone to castasterone. May also convert 6-deoxoteasterone to teasterone, 3-dehydro-6-deoxoteasterone to 3-dehydroteasterone, and 6-deoxotyphasterol to typhasterol, but not castasterone to brassinolide; Belongs to the cytochrome P450 family. (464 aa)
	CYP85A3	Cytochrome P450 85A3; Catalyzes the C6-oxidation step in brassinosteroids biosynthesis. Converts 6-deoxocastasterone to castasterone, and castasterone to brassinolide; Belongs to the cytochrome P450 family. (467 aa)
	DET2	Steroid 5-alpha-reductase DET2; Involved in a reduction step in the biosynthesis of the plant steroid, brassinolide. Can use progesterone, testosterone, androstenedione and campestenone as substrate. (257 aa)

Your Current Organism:

Solanum lycopersicum

NCBI taxonomy Id: 4081
Other names: Lycopersicon esculentum, Lycopersicon esculentum Mill., Lycopersicon esculentum var. esculentum, S. lycopersicum, Solanum esculentum, Solanum esculentum Dunal, Solanum lycopersicum L., Solanum lycopersicum var. humboldtii, tomato

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A3Q7E9H9	A0A3Q7F7B3	A0A3Q7E9H9	A0A3Q7F7B3	Uncharacterized protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.490
A0A3Q7E9H9	A0A3Q7FVN9	A0A3Q7E9H9	A0A3Q7FVN9	Uncharacterized protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.419
A0A3Q7E9H9	A0A3Q7H0B6	A0A3Q7E9H9	A0A3Q7H0B6	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A3Q7E9H9	CYP90B3	A0A3Q7E9H9	A0A3Q7FV39	Uncharacterized protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.527
A0A3Q7E9H9	SSR2	A0A3Q7E9H9	A0A0C6G3Q8	Uncharacterized protein.	Sterol side chain reductase.	0.964
A0A3Q7E9H9	SlSSR1	A0A3Q7E9H9	A0A3Q7EY91	Uncharacterized protein.	FAD-binding PCMH-type domain-containing protein.	0.965
A0A3Q7EII3	A0A3Q7IC09	A0A3Q7EII3	A0A3Q7IC09	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.905
A0A3Q7EII3	A0A3Q7J325	A0A3Q7EII3	A0A3Q7J325	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.904
A0A3Q7F7B3	A0A3Q7E9H9	A0A3Q7F7B3	A0A3Q7E9H9	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.490
A0A3Q7F7B3	A0A3Q7FVN9	A0A3Q7F7B3	A0A3Q7FVN9	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.902
A0A3Q7F7B3	A0A3Q7H0B6	A0A3Q7F7B3	A0A3Q7H0B6	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.490
A0A3Q7F7B3	A0A3Q7HY94	A0A3Q7F7B3	A0A3Q7HY94	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.942
A0A3Q7F7B3	CYP724B2	A0A3Q7F7B3	A0A3Q7HFY0	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.907
A0A3Q7F7B3	CYP85A1	A0A3Q7F7B3	Q43147	Uncharacterized protein; Belongs to the cytochrome P450 family.	Cytochrome P450 85A1; Catalyzes the C6-oxidation step in brassinosteroids biosynthesis. Converts 6-deoxocastasterone to castasterone. May also convert 6-deoxoteasterone to teasterone, 3-dehydro-6-deoxoteasterone to 3-dehydroteasterone, and 6-deoxotyphasterol to typhasterol, but not castasterone to brassinolide; Belongs to the cytochrome P450 family.	0.908
A0A3Q7F7B3	CYP85A3	A0A3Q7F7B3	Q50LE0	Uncharacterized protein; Belongs to the cytochrome P450 family.	Cytochrome P450 85A3; Catalyzes the C6-oxidation step in brassinosteroids biosynthesis. Converts 6-deoxocastasterone to castasterone, and castasterone to brassinolide; Belongs to the cytochrome P450 family.	0.908
A0A3Q7F7B3	CYP90B3	A0A3Q7F7B3	A0A3Q7FV39	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.907
A0A3Q7F7B3	DET2	A0A3Q7F7B3	Q5K2N1	Uncharacterized protein; Belongs to the cytochrome P450 family.	Steroid 5-alpha-reductase DET2; Involved in a reduction step in the biosynthesis of the plant steroid, brassinolide. Can use progesterone, testosterone, androstenedione and campestenone as substrate.	0.942
A0A3Q7F7B3	K4C5W4_SOLLC	A0A3Q7F7B3	K4C5W4	Uncharacterized protein; Belongs to the cytochrome P450 family.	CYP90A1-like protein; Belongs to the cytochrome P450 family.	0.905
A0A3Q7FVN9	A0A3Q7E9H9	A0A3Q7FVN9	A0A3Q7E9H9	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.419
A0A3Q7FVN9	A0A3Q7F7B3	A0A3Q7FVN9	A0A3Q7F7B3	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.902

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