(38 nodes) Ribosomal protein S5 domain 2-type fold, subgroup network (Solanum lycopersicum)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	A0A3Q7FYB9	Uncharacterized protein. (355 aa)
	ISPE	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic/chromoplastic; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (401 aa)
	K4DGB2_SOLLC	Uncharacterized protein. (226 aa)
	MDC	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprene-containing compounds such as sterols and terpenoids. Belongs to the diphosphomevalonate decarboxylase family. (422 aa)
	A0A494G9J3	OMP_b-brl_2 domain-containing protein. (810 aa)
	A0A494G8P7	Uncharacterized protein. (1015 aa)
	A0A3Q7JUG1	DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner. (729 aa)
	A0A3Q7JFC5	Methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family. (727 aa)
	A0A3Q7J0S0	Tr-type G domain-containing protein. (1024 aa)
	A0A3Q7IRK5	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (839 aa)
	A0A3Q7IP94	Elongation factor G, chloroplastic; Chloroplast-localized elongation factor EF-G involved in protein synthesis in plastids. Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl- tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (787 aa)
	A0A3Q7IJ97	Tr-type G domain-containing protein. (843 aa)
	A0A3Q7IDE9	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (972 aa)
	A0A3Q7I7B5	Uncharacterized protein. (1255 aa)
	A0A3Q7I1S8	Uncharacterized protein. (412 aa)
	A0A3Q7I0H0	Tr-type G domain-containing protein. (987 aa)
	A0A3Q7HU70	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (877 aa)
	A0A3Q7HTG9	Uncharacterized protein. (509 aa)
	A0A3Q7HMR2	Tr-type G domain-containing protein. (843 aa)
	A0A3Q7H8W1	Uncharacterized protein. (995 aa)
	A0A3Q7H2J3	RBR-type E3 ubiquitin transferase; Belongs to the universal ribosomal protein uS9 family. (739 aa)
	A0A3Q7GW90	GHMP_kinases_N domain-containing protein. (509 aa)
	A0A3Q7GU88	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family. (147 aa)
	A0A3Q7GDB0	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family. (147 aa)
	A0A3Q7G7F0	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (280 aa)
	A0A3Q7G5P1	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (280 aa)
	MLH1	DNA_mis_repair domain-containing protein. (739 aa)
	A0A3Q7G080	Diphosphomevalonate decarboxylase. (308 aa)
	A0A3Q7FVG0	RECA_2 domain-containing protein. (654 aa)
	A0A3Q7FTH2	Uncharacterized protein. (1217 aa)
	A0A3Q7F3S5	Uncharacterized protein; Belongs to the universal ribosomal protein uS5 family. (904 aa)
	A0A3Q7F0F8	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family. (150 aa)
	A0A3Q7EUH2	Topo-VIb_trans domain-containing protein. (411 aa)
	A0A3Q7EN40	Mevalonate kinase. (392 aa)
	A0A3Q7EKR8	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (766 aa)
	A0A3Q7EJJ5	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1478 aa)
	A0A3Q7EEN4	Uncharacterized protein. (500 aa)
	A0A3Q7EA63	GHMP_kinases_N domain-containing protein. (400 aa)

Your Current Organism:

Solanum lycopersicum

NCBI taxonomy Id: 4081
Other names: Lycopersicon esculentum, Lycopersicon esculentum Mill., Lycopersicon esculentum var. esculentum, S. lycopersicum, Solanum esculentum, Solanum esculentum Dunal, Solanum lycopersicum L., Solanum lycopersicum var. humboldtii, tomato

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A3Q7EA63	A0A3Q7EN40	A0A3Q7EA63	A0A3Q7EN40	GHMP_kinases_N domain-containing protein.	Mevalonate kinase.	0.622
A0A3Q7EA63	A0A3Q7G080	A0A3Q7EA63	A0A3Q7G080	GHMP_kinases_N domain-containing protein.	Diphosphomevalonate decarboxylase.	0.544
A0A3Q7EA63	A0A3Q7GW90	A0A3Q7EA63	A0A3Q7GW90	GHMP_kinases_N domain-containing protein.	GHMP_kinases_N domain-containing protein.	0.596
A0A3Q7EA63	A0A3Q7HTG9	A0A3Q7EA63	A0A3Q7HTG9	GHMP_kinases_N domain-containing protein.	Uncharacterized protein.	0.596
A0A3Q7EA63	MDC	A0A3Q7EA63	A8WBX7	GHMP_kinases_N domain-containing protein.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprene-containing compounds such as sterols and terpenoids. Belongs to the diphosphomevalonate decarboxylase family.	0.551
A0A3Q7EEN4	A0A3Q7EN40	A0A3Q7EEN4	A0A3Q7EN40	Uncharacterized protein.	Mevalonate kinase.	0.420
A0A3Q7EJJ5	A0A3Q7J0S0	A0A3Q7EJJ5	A0A3Q7J0S0	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Tr-type G domain-containing protein.	0.403
A0A3Q7EKR8	A0A3Q7F0F8	A0A3Q7EKR8	A0A3Q7F0F8	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.796
A0A3Q7EKR8	A0A3Q7F3S5	A0A3Q7EKR8	A0A3Q7F3S5	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.	Uncharacterized protein; Belongs to the universal ribosomal protein uS5 family.	0.847
A0A3Q7EKR8	A0A3Q7G5P1	A0A3Q7EKR8	A0A3Q7G5P1	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	0.874
A0A3Q7EKR8	A0A3Q7G7F0	A0A3Q7EKR8	A0A3Q7G7F0	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	0.874
A0A3Q7EKR8	A0A3Q7GDB0	A0A3Q7EKR8	A0A3Q7GDB0	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.796
A0A3Q7EKR8	A0A3Q7GU88	A0A3Q7EKR8	A0A3Q7GU88	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.796
A0A3Q7EN40	A0A3Q7EA63	A0A3Q7EN40	A0A3Q7EA63	Mevalonate kinase.	GHMP_kinases_N domain-containing protein.	0.622
A0A3Q7EN40	A0A3Q7EEN4	A0A3Q7EN40	A0A3Q7EEN4	Mevalonate kinase.	Uncharacterized protein.	0.420
A0A3Q7EN40	A0A3Q7FYB9	A0A3Q7EN40	A0A3Q7FYB9	Mevalonate kinase.	Uncharacterized protein.	0.599
A0A3Q7EN40	A0A3Q7G080	A0A3Q7EN40	A0A3Q7G080	Mevalonate kinase.	Diphosphomevalonate decarboxylase.	0.989
A0A3Q7EN40	A0A3Q7GW90	A0A3Q7EN40	A0A3Q7GW90	Mevalonate kinase.	GHMP_kinases_N domain-containing protein.	0.995
A0A3Q7EN40	A0A3Q7H8W1	A0A3Q7EN40	A0A3Q7H8W1	Mevalonate kinase.	Uncharacterized protein.	0.420
A0A3Q7EN40	A0A3Q7HTG9	A0A3Q7EN40	A0A3Q7HTG9	Mevalonate kinase.	Uncharacterized protein.	0.995

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