(42 nodes) (2019) Application of Data-Independent Acquisition Approach to Study the Proteome Change from Early to Later Phases of Tomato Pathogenesis Responses. network (Solanum lycopersicum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A3Q7H039	Uncharacterized protein. (552 aa)
	ARG2	Uncharacterized protein; Belongs to the arginase family. (664 aa)
	TomloxE	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (1520 aa)
	A0A3Q7EN25	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (1634 aa)
	A0A3Q7ENA3	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (859 aa)
	A0A3Q7ENA4	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (854 aa)
	A0A3Q7EQL9	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (394 aa)
	TomloxC	Uncharacterized protein. (557 aa)
	A0A3Q7ET25	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (912 aa)
	A0A3Q7F174	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (359 aa)
	A0A3Q7F755	Thioredoxin; Belongs to the thioredoxin family. (118 aa)
	A0A3Q7FRV3	Thioredoxin; Belongs to the thioredoxin family. (125 aa)
	CNX61.0	Uncharacterized protein. (748 aa)
	LoxD	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (908 aa)
	A0A3Q7FX86	Thioredoxin; Belongs to the thioredoxin family. (133 aa)
	A0A3Q7G9Y3	Thioredoxin; Belongs to the thioredoxin family. (135 aa)
	A0A3Q7GBG5	Thioredoxin; Belongs to the thioredoxin family. (139 aa)
	A0A3Q7GDK8	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (911 aa)
	A0A3Q7GE00	Thioredoxin; Belongs to the thioredoxin family. (135 aa)
	HSP90	HATPase_c domain-containing protein. (704 aa)
	A0A3Q7HN01	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (861 aa)
	PR1a2	Uncharacterized protein; Belongs to the CRISP family. (488 aa)
	A0A3Q7I7A9	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (1731 aa)
	A0A3Q7I8A0	Glutathione reductase; Maintains high levels of reduced glutathione. (508 aa)
	A0A3Q7IMD9	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (390 aa)
	HSP70	Uncharacterized protein; Belongs to the heat shock protein 70 family. (692 aa)
	A0A3Q7IXS9	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (510 aa)
	GR	Glutathione reductase; Maintains high levels of reduced glutathione. (557 aa)
	A0A3Q7JDI3	Chitin-binding type-1 domain-containing protein. (322 aa)
	A0A3Q7JEH3	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (414 aa)
	A0A3Q7JSV3	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (538 aa)
	gst	Glutathione-S-transferase; Belongs to the GST superfamily. (224 aa)
	G8Z278_SOLLC	Hop-interacting protein THI111. (407 aa)
	K4BM07_SOLLC	Thioredoxin; Belongs to the thioredoxin family. (122 aa)
	NIM1	NPR1. (576 aa)
	PR1B1	Pathogenesis-related leaf protein 6; Probably involved in the defense reaction of plants against pathogens. Has antifungal activity. (159 aa)
	ACO1	1-aminocyclopropane-1-carboxylate oxidase 1. (315 aa)
	ZEP	Zeaxanthin epoxidase, chloroplastic; Converts zeaxanthin into antheraxanthin and subsequently violaxanthin. Involved in the epoxidation of zeaxanthin. Plays an important role in resistance to stresses, seed development and dormancy. (669 aa)
	P4	Pathogenesis-related leaf protein 4; Probably involved in the defense reaction of plants against pathogens. (159 aa)
	PR-1a1	Pathogenesis-related protein 1A1; Probably involved in the defense reaction of plants against pathogens; Belongs to the CRISP family. (175 aa)
	APX	Ascorbate peroxidase; Belongs to the peroxidase family. (250 aa)
	LoxF	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. (447 aa)

Your Current Organism:

Solanum lycopersicum

NCBI taxonomy Id: 4081
Other names: Lycopersicon esculentum, Lycopersicon esculentum Mill., Lycopersicon esculentum var. esculentum, S. lycopersicum, Solanum esculentum, Solanum esculentum Dunal, Solanum lycopersicum L., Solanum lycopersicum var. humboldtii, tomato

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A3Q7EN25	A0A3Q7F755	A0A3Q7EN25	A0A3Q7F755	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Thioredoxin; Belongs to the thioredoxin family.	0.462
A0A3Q7EN25	A0A3Q7FRV3	A0A3Q7EN25	A0A3Q7FRV3	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Thioredoxin; Belongs to the thioredoxin family.	0.415
A0A3Q7EN25	A0A3Q7GDK8	A0A3Q7EN25	A0A3Q7GDK8	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	0.666
A0A3Q7EN25	A0A3Q7I8A0	A0A3Q7EN25	A0A3Q7I8A0	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Glutathione reductase; Maintains high levels of reduced glutathione.	0.526
A0A3Q7EN25	A0A3Q7IXS9	A0A3Q7EN25	A0A3Q7IXS9	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	0.660
A0A3Q7EN25	A0A3Q7JSV3	A0A3Q7EN25	A0A3Q7JSV3	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	0.662
A0A3Q7EN25	APX	A0A3Q7EN25	Q52QQ4	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Ascorbate peroxidase; Belongs to the peroxidase family.	0.717
A0A3Q7EN25	GR	A0A3Q7EN25	A0A3Q7J0B1	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Glutathione reductase; Maintains high levels of reduced glutathione.	0.524
A0A3Q7EN25	LoxD	A0A3Q7EN25	A0A3Q7FWG1	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	0.663
A0A3Q7EN25	LoxF	A0A3Q7EN25	A0A3Q7E8Z0	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	0.660
A0A3Q7EN25	NIM1	A0A3Q7EN25	K4CDU6	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	NPR1.	0.560
A0A3Q7EN25	PR1B1	A0A3Q7EN25	P04284	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Pathogenesis-related leaf protein 6; Probably involved in the defense reaction of plants against pathogens. Has antifungal activity.	0.462
A0A3Q7EN25	TomloxC	A0A3Q7EN25	A0A3Q7ERA8	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Uncharacterized protein.	0.650
A0A3Q7ENA3	A0A3Q7F755	A0A3Q7ENA3	A0A3Q7F755	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Thioredoxin; Belongs to the thioredoxin family.	0.461
A0A3Q7ENA3	A0A3Q7FRV3	A0A3Q7ENA3	A0A3Q7FRV3	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Thioredoxin; Belongs to the thioredoxin family.	0.406
A0A3Q7ENA3	A0A3Q7I8A0	A0A3Q7ENA3	A0A3Q7I8A0	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Glutathione reductase; Maintains high levels of reduced glutathione.	0.525
A0A3Q7ENA3	APX	A0A3Q7ENA3	Q52QQ4	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Ascorbate peroxidase; Belongs to the peroxidase family.	0.718
A0A3Q7ENA3	GR	A0A3Q7ENA3	A0A3Q7J0B1	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Glutathione reductase; Maintains high levels of reduced glutathione.	0.525
A0A3Q7ENA3	NIM1	A0A3Q7ENA3	K4CDU6	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	NPR1.	0.554
A0A3Q7ENA3	PR1B1	A0A3Q7ENA3	P04284	Lipoxygenase; Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.	Pathogenesis-related leaf protein 6; Probably involved in the defense reaction of plants against pathogens. Has antifungal activity.	0.462

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