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A0A3Q7E8I1 A0A3Q7E8I1 SCOA-2 SCOA-2 A0A3Q7EHA9 A0A3Q7EHA9 A0A3Q7ENY7 A0A3Q7ENY7 A0A3Q7EPC2 A0A3Q7EPC2 A0A3Q7EYC4 A0A3Q7EYC4 A0A3Q7EZ95 A0A3Q7EZ95 A0A3Q7F6D8 A0A3Q7F6D8 A0A3Q7F7G5 A0A3Q7F7G5 A0A3Q7F897 A0A3Q7F897 A0A3Q7FQ43 A0A3Q7FQ43 A0A3Q7FWL2 A0A3Q7FWL2 A0A3Q7FX41 A0A3Q7FX41 A0A3Q7FZL0 A0A3Q7FZL0 A0A3Q7G266 A0A3Q7G266 A0A3Q7G2H1 A0A3Q7G2H1 A0A3Q7G512 A0A3Q7G512 A0A3Q7G917 A0A3Q7G917 A0A3Q7G9B3 A0A3Q7G9B3 A0A3Q7GC36 A0A3Q7GC36 A0A3Q7GDJ7 A0A3Q7GDJ7 A0A3Q7GH43 A0A3Q7GH43 A0A3Q7GLT1 A0A3Q7GLT1 A0A3Q7GNY6 A0A3Q7GNY6 A0A3Q7H441 A0A3Q7H441 A0A3Q7H5I5 A0A3Q7H5I5 A0A3Q7HBK4 A0A3Q7HBK4 A0A3Q7HBW2 A0A3Q7HBW2 A0A3Q7HFR4 A0A3Q7HFR4 MMDH1 MMDH1 A0A3Q7HH10 A0A3Q7HH10 A0A3Q7HIF6 A0A3Q7HIF6 A0A3Q7HJL9 A0A3Q7HJL9 A0A3Q7HUE5 A0A3Q7HUE5 A0A3Q7HV38 A0A3Q7HV38 A0A3Q7I742 A0A3Q7I742 A0A3Q7I7B3 A0A3Q7I7B3 A0A3Q7IPV0 A0A3Q7IPV0 A0A3Q7IT31 A0A3Q7IT31 Slalpha-kGDH Slalpha-kGDH A0A3Q7J2T1 A0A3Q7J2T1 A0A3Q7J330 A0A3Q7J330 A0A3Q7J3Q3 A0A3Q7J3Q3 A0A3Q7J4V1 A0A3Q7J4V1 A0A3Q7JCG7 A0A3Q7JCG7 ICDH1 ICDH1 A0A3Q7JEL1 A0A3Q7JEL1 A0A3Q7JEN8 A0A3Q7JEN8 A0A3Q7JS72 A0A3Q7JS72 D2KQI9_SOLLC D2KQI9_SOLLC gMDH gMDH SUCA2_SOLLC SUCA2_SOLLC Q8GT30_SOLLC Q8GT30_SOLLC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A3Q7E8I1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (415 aa)
SCOA-2Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (332 aa)
A0A3Q7EHA9Citrate synthase; Belongs to the citrate synthase family. (470 aa)
A0A3Q7ENY7Uncharacterized protein; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (574 aa)
A0A3Q7EPC2Uncharacterized protein. (423 aa)
A0A3Q7EYC4Ligase_CoA domain-containing protein. (608 aa)
A0A3Q7EZ95Malate dehydrogenase. (352 aa)
A0A3Q7F6D8Iso_dh domain-containing protein. (357 aa)
A0A3Q7F7G5Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (629 aa)
A0A3Q7F897Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (483 aa)
A0A3Q7FQ43Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (125 aa)
A0A3Q7FWL2Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (391 aa)
A0A3Q7FX41Transket_pyr domain-containing protein. (1020 aa)
A0A3Q7FZL0Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (408 aa)
A0A3Q7G266Uncharacterized protein. (421 aa)
A0A3Q7G2H14Fe-4S ferredoxin-type domain-containing protein. (309 aa)
A0A3Q7G512Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (299 aa)
A0A3Q7G917Uncharacterized protein. (423 aa)
A0A3Q7G9B3Uncharacterized protein. (662 aa)
A0A3Q7GC36Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (391 aa)
A0A3Q7GDJ7Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (459 aa)
A0A3Q7GH43Uncharacterized protein. (528 aa)
A0A3Q7GLT1Uncharacterized protein. (571 aa)
A0A3Q7GNY6Uncharacterized protein. (488 aa)
A0A3Q7H441Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (553 aa)
A0A3Q7H5I5Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (421 aa)
A0A3Q7HBK4Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (995 aa)
A0A3Q7HBW2Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (372 aa)
A0A3Q7HFR4Citrate synthase. (511 aa)
MMDH1Malate dehydrogenase. (348 aa)
A0A3Q7HH10Transket_pyr domain-containing protein. (846 aa)
A0A3Q7HIF6Lipoyl-binding domain-containing protein. (468 aa)
A0A3Q7HJL9Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (408 aa)
A0A3Q7HUE5Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (717 aa)
A0A3Q7HV38Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (367 aa)
A0A3Q7I742Uncharacterized protein. (494 aa)
A0A3Q7I7B3Malate dehydrogenase. (339 aa)
A0A3Q7IPV0Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (644 aa)
A0A3Q7IT31Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (468 aa)
Slalpha-kGDHLipoyl-binding domain-containing protein. (468 aa)
A0A3Q7J2T1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (981 aa)
A0A3Q7J330Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (440 aa)
A0A3Q7J3Q3Uncharacterized protein. (412 aa)
A0A3Q7J4V1Citrate synthase. (514 aa)
A0A3Q7JCG7Uncharacterized protein. (648 aa)
ICDH1Iso_dh domain-containing protein. (373 aa)
A0A3Q7JEL1Ligase_CoA domain-containing protein. (608 aa)
A0A3Q7JEN8Dihydrolipoyl dehydrogenase. (504 aa)
A0A3Q7JS72Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (440 aa)
D2KQI9_SOLLCSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (274 aa)
gMDHGlyoxisomal malate dehydrogenase; Belongs to the LDH/MDH superfamily. (357 aa)
SUCA2_SOLLCSuccinate--CoA ligase [ADP-forming] subunit alpha-2, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (337 aa)
Q8GT30_SOLLCDihydrolipoyl dehydrogenase. (500 aa)
Your Current Organism:
Solanum lycopersicum
NCBI taxonomy Id: 4081
Other names: Lycopersicon esculentum, Lycopersicon esculentum Mill., Lycopersicon esculentum var. esculentum, S. lycopersicum, Solanum esculentum, Solanum esculentum Dunal, Solanum lycopersicum L., Solanum lycopersicum var. humboldtii, tomato
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