(10 nodes) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex, and DNA-binding protein RHL1 network (Nicotiana tabacum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107761646	DNA-binding protein BIN4-like. (404 aa)
	LOC107764270	DNA topoisomerase 6 subunit B-like. (181 aa)
	LOC107765455	Uncharacterized protein LOC107765455. (251 aa)
	LOC107779586	DNA-binding protein BIN4-like isoform X1. (404 aa)
	LOC107786355	DNA topoisomerase 6 subunit A; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (420 aa)
	LOC107791525	DNA topoisomerase 6 subunit A; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (420 aa)
	LOC107798097	DNA-binding protein RHL1-like isoform X1. (382 aa)
	LOC107808977	Uncharacterized protein LOC107808977. (165 aa)
	LOC107815486	DNA topoisomerase 6 subunit B; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP; Belongs to the TOP6B family. (580 aa)
	LOC107821159	DNA-binding protein RHL1-like isoform X1. (393 aa)

Your Current Organism:

Nicotiana tabacum

NCBI taxonomy Id: 4097
Other names: American tobacco, N. tabacum, Nicotiana tabacum L., common tobacco, tobacco

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC107761646	LOC107764270	A0A1S3X6A8	A0A1S3XEK2	DNA-binding protein BIN4-like.	DNA topoisomerase 6 subunit B-like.	0.576
LOC107761646	LOC107779586	A0A1S3X6A8	A0A1S3YTJ8	DNA-binding protein BIN4-like.	DNA-binding protein BIN4-like isoform X1.	0.544
LOC107761646	LOC107786355	A0A1S3X6A8	A0A1S3ZG35	DNA-binding protein BIN4-like.	DNA topoisomerase 6 subunit A; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity.	0.694
LOC107761646	LOC107791525	A0A1S3X6A8	A0A1S3ZXM9	DNA-binding protein BIN4-like.	DNA topoisomerase 6 subunit A; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity.	0.694
LOC107761646	LOC107798097	A0A1S3X6A8	A0A1S4AIV7	DNA-binding protein BIN4-like.	DNA-binding protein RHL1-like isoform X1.	0.671
LOC107761646	LOC107815486	A0A1S3X6A8	A0A1S4C6K2	DNA-binding protein BIN4-like.	DNA topoisomerase 6 subunit B; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP; Belongs to the TOP6B family.	0.717
LOC107761646	LOC107821159	A0A1S3X6A8	A0A1S4CPR2	DNA-binding protein BIN4-like.	DNA-binding protein RHL1-like isoform X1.	0.672
LOC107764270	LOC107761646	A0A1S3XEK2	A0A1S3X6A8	DNA topoisomerase 6 subunit B-like.	DNA-binding protein BIN4-like.	0.576
LOC107764270	LOC107779586	A0A1S3XEK2	A0A1S3YTJ8	DNA topoisomerase 6 subunit B-like.	DNA-binding protein BIN4-like isoform X1.	0.576
LOC107764270	LOC107786355	A0A1S3XEK2	A0A1S3ZG35	DNA topoisomerase 6 subunit B-like.	DNA topoisomerase 6 subunit A; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity.	0.955
LOC107764270	LOC107791525	A0A1S3XEK2	A0A1S3ZXM9	DNA topoisomerase 6 subunit B-like.	DNA topoisomerase 6 subunit A; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity.	0.955
LOC107764270	LOC107798097	A0A1S3XEK2	A0A1S4AIV7	DNA topoisomerase 6 subunit B-like.	DNA-binding protein RHL1-like isoform X1.	0.595
LOC107764270	LOC107821159	A0A1S3XEK2	A0A1S4CPR2	DNA topoisomerase 6 subunit B-like.	DNA-binding protein RHL1-like isoform X1.	0.593
LOC107779586	LOC107761646	A0A1S3YTJ8	A0A1S3X6A8	DNA-binding protein BIN4-like isoform X1.	DNA-binding protein BIN4-like.	0.544
LOC107779586	LOC107764270	A0A1S3YTJ8	A0A1S3XEK2	DNA-binding protein BIN4-like isoform X1.	DNA topoisomerase 6 subunit B-like.	0.576
LOC107779586	LOC107786355	A0A1S3YTJ8	A0A1S3ZG35	DNA-binding protein BIN4-like isoform X1.	DNA topoisomerase 6 subunit A; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity.	0.694
LOC107779586	LOC107791525	A0A1S3YTJ8	A0A1S3ZXM9	DNA-binding protein BIN4-like isoform X1.	DNA topoisomerase 6 subunit A; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity.	0.694
LOC107779586	LOC107798097	A0A1S3YTJ8	A0A1S4AIV7	DNA-binding protein BIN4-like isoform X1.	DNA-binding protein RHL1-like isoform X1.	0.696
LOC107779586	LOC107815486	A0A1S3YTJ8	A0A1S4C6K2	DNA-binding protein BIN4-like isoform X1.	DNA topoisomerase 6 subunit B; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP; Belongs to the TOP6B family.	0.717
LOC107779586	LOC107821159	A0A1S3YTJ8	A0A1S4CPR2	DNA-binding protein BIN4-like isoform X1.	DNA-binding protein RHL1-like isoform X1.	0.698