(105 nodes) Ubiquitin conjugating enzyme activity, and E3 ubiquitin-protein ligase HECTD1/TRIP12-like network (Nicotiana tabacum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Fni3	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
	Ubc13-2	Ubiquitin-conjugating enzyme E2 36-like protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
	LOC107759180	Probable ubiquitin-conjugating enzyme E2 18; Belongs to the ubiquitin-conjugating enzyme family. (161 aa)
	LOC107759736	ubiquitin-60S ribosomal protein L40. (128 aa)
	LOC107760919	Fatty acid desaturase 4, chloroplastic-like. (339 aa)
	LOC107761107	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (414 aa)
	LOC107761315	Ubiquitin-conjugating enzyme E2 4-like isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	LOC107762511	Ubiquitin-conjugating enzyme E2 34-like. (231 aa)
	LOC107763564	LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase UPL3-like. (1845 aa)
	LOC107766185	E3 ubiquitin protein ligase. (849 aa)
	LOC107766688	Ubiquitin-conjugating enzyme E2 32-like. (299 aa)
	LOC107767217	E3 ubiquitin-protein ligase UPL3. (1824 aa)
	LOC107767426	F-box protein At5g07610-like. (376 aa)
	LOC107767854	ubiquitin-60S ribosomal protein L40. (128 aa)
	LOC107767930	Ubiquitin-conjugating enzyme E2 7-like; Belongs to the ubiquitin-conjugating enzyme family. (169 aa)
	LOC107768369	Ubiquitin-conjugating enzyme E2 10-like; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
	LOC107769260	Polyubiquitin 11. (186 aa)
	LOC107769653	Uncharacterized protein LOC107769653 isoform X1. (410 aa)
	LOC107769767	Probable ubiquitin-conjugating enzyme E2 16; Belongs to the ubiquitin-conjugating enzyme family. (100 aa)
	LOC107775245	Ubiquitin-conjugating enzyme E2 34-like. (231 aa)
	LOC107775515	E3 ubiquitin-protein ligase KEG-like. (1618 aa)
	LOC107775817	Ubiquitin-conjugating enzyme E2 2-like isoform X1. (156 aa)
	LOC107775987	Ubiquitin-conjugating enzyme E2 32-like. (301 aa)
	LOC107776491	Probable ubiquitin-conjugating enzyme E2 18; Belongs to the ubiquitin-conjugating enzyme family. (161 aa)
	LOC107777419	Ubiquitin-conjugating enzyme E2 28-like isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
	LOC107777942	Uncharacterized protein LOC107777942 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (574 aa)
	LOC107781334	Ubiquitin-conjugating enzyme E2 28-like; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
	LOC107782023	Ubiquitin-conjugating enzyme E2-17 kDa-like; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
	LOC107782760	E3 ubiquitin-protein ligase UPL3-like. (1268 aa)
	LOC107783068	E3 ubiquitin protein ligase. (884 aa)
	LOC107784606	Ubiquitin-conjugating enzyme E2 7 isoform X2; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
	LOC107785213	E3 ubiquitin-protein ligase UPL4-like isoform X1. (1541 aa)
	LOC107786522	Ubiquitin-activating enzyme E1 1-like; Belongs to the ubiquitin-activating E1 family. (1080 aa)
	LOC107786534	Ubiquitin-conjugating enzyme E2 27-like. (81 aa)
	LOC107788577	Ubiquitin-conjugating enzyme E2-17 kDa-like. (118 aa)
	LOC107788813	Ubiquitin-conjugating enzyme E2-23 kDa-like; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	LOC107788958	Uncharacterized protein LOC107788958. (593 aa)
	LOC107788956	Ubiquitin-conjugating enzyme E2 34-like. (239 aa)
	LOC107788973	Fatty acid desaturase 4, chloroplastic-like. (338 aa)
	LOC107789547	Ubiquitin-conjugating enzyme E2 5B-like; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
	LOC107790696	Ubiquitin-conjugating enzyme E2 34-like. (239 aa)
	LOC107790700	Uncharacterized protein LOC107790700. (593 aa)
	LOC107791260	Ubiquitin-conjugating enzyme E2-17 kDa-like; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
	LOC107791414	E3 ubiquitin-protein ligase UPL3-like. (908 aa)
	LOC107792179	Putative ubiquitin-conjugating enzyme E2 38 isoform X1. (465 aa)
	LOC107793006	Ubiquitin-conjugating enzyme E2 variant 1D-like. (146 aa)
	LOC107793416	E3 ubiquitin protein ligase. (849 aa)
	LOC107793496	Ubiquitin-conjugating enzyme E2-23 kDa-like; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	LOC107793770	E3 ubiquitin protein ligase. (884 aa)
	LOC107793857	Ubiquitin-activating enzyme E1 1-like; Belongs to the ubiquitin-activating E1 family. (1092 aa)
	LOC107794380	Ubiquitin-conjugating enzyme E2 27-like. (106 aa)
	LOC107794743	Ubiquitin-conjugating enzyme E2-23 kDa-like; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	LOC107795599	Ubiquitin-conjugating enzyme E2 10; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
	LOC107795844	Ubiquitin-conjugating enzyme E2-23 kDa-like; Belongs to the ubiquitin-conjugating enzyme family. (247 aa)
	LOC107796639	Probable ubiquitin-conjugating enzyme E2 18. (116 aa)
	LOC107797361	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1887 aa)
	LOC107798409	E3 ubiquitin-protein ligase UPL3-like. (848 aa)
	LOC107798708	Ubiquitin-conjugating enzyme E2-23 kDa-like; Belongs to the ubiquitin-conjugating enzyme family. (185 aa)
	LOC107799069	ubiquitin-40S ribosomal protein S27a-like. (156 aa)
	LOC107799066	Probable ubiquitin-conjugating enzyme E2 18. (168 aa)
	LOC107799978	F-box protein At5g07610-like. (379 aa)
	LOC107800616	Ubiquitin thioesterase. (301 aa)
	LOC107801240	BTB/POZ domain-containing protein At2g30600-like isoform X1. (826 aa)
	LOC107802689	Ubiquitin-like isoform X1. (129 aa)
	LOC107804146	Ubiquitin-conjugating enzyme E2 28-like isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (239 aa)
	LOC107804278	Uncharacterized protein LOC107804278. (276 aa)
	LOC107804942	SUMO-conjugating enzyme UBC9-like; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
	LOC107806064	Ubiquitin-conjugating enzyme E2 2-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	LOC107806158	E3 ubiquitin-protein ligase KEG-like. (1625 aa)
	LOC107806522	Ubiquitin-conjugating enzyme E2 28-like isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
	LOC107806663	BTB/POZ domain-containing protein At2g30600-like isoform X1. (824 aa)
	LOC107807144	Phosphatidylinositol 4-kinase gamma 4-like; Belongs to the PI3/PI4-kinase family. (584 aa)
	LOC107807136	Ubiquitin-conjugating enzyme E2 2 isoform X2. (146 aa)
	LOC107807583	NEDD8-activating enzyme E1 catalytic subunit-like. (186 aa)
	LOC107809255	Ubiquitin-conjugating enzyme E2 7-like; Belongs to the ubiquitin-conjugating enzyme family. (109 aa)
	LOC107809646	Uncharacterized protein LOC107809646 isoform X1. (412 aa)
	LOC107810039	Ubiquitin-conjugating enzyme E2 2-like. (208 aa)
	LOC107810129	E3 ubiquitin-protein ligase PRT1. (432 aa)
	LOC107810175	Ubiquitin-conjugating enzyme E2 4-like; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	LOC107810677	Ubiquitin-conjugating enzyme E2 27-like. (113 aa)
	LOC107812668	Ubiquitin-conjugating enzyme E2 2-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	LOC107814408	Ubiquitin thioesterase. (296 aa)
	LOC107815862	Ubiquitin-conjugating enzyme E2 27-like. (116 aa)
	LOC107816141	Constitutive photomorphogenesis protein 10. (176 aa)
	LOC107816375	Ubiquitin-activating enzyme E1 1-like; Belongs to the ubiquitin-activating E1 family. (1080 aa)
	LOC107816778	Ubiquitin-conjugating enzyme E2 2-like; Belongs to the ubiquitin-conjugating enzyme family. (209 aa)
	LOC107819396	Ubiquitin-conjugating enzyme E2 7 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (168 aa)
	LOC107820058	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2050 aa)
	LOC107820117	Ubiquitin-conjugating enzyme E2 7-like; Belongs to the ubiquitin-conjugating enzyme family. (169 aa)
	LOC107820910	Ubiquitin-conjugating enzyme E2 28-like; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
	LOC107821932	E3 ubiquitin-protein ligase UPL4-like isoform X1. (1539 aa)
	LOC107822697	Ubiquitin-conjugating enzyme E2 2-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	LOC107823977	ubiquitin-NEDD8-like protein RUB2 isoform X1. (154 aa)
	LOC107824081	Probable ubiquitin-conjugating enzyme E2 16; Belongs to the ubiquitin-conjugating enzyme family. (161 aa)
	LOC107824880	Probable ubiquitin-conjugating enzyme E2 18; Belongs to the ubiquitin-conjugating enzyme family. (161 aa)
	LOC107826039	E3 ubiquitin-protein ligase UPL3-like. (399 aa)
	LOC107826943	E3 ubiquitin-protein ligase UPL3-like. (92 aa)
	LOC107827608	ubiquitin-NEDD8-like protein RUB2. (154 aa)
	LOC107827781	ubiquitin-NEDD8-like protein RUB1. (179 aa)
	LOC107829201	Ubiquitin-conjugating enzyme E2 variant 1D. (146 aa)
	LOC107829766	Ubiquitin-activating enzyme E1 1-like; Belongs to the ubiquitin-activating E1 family. (1092 aa)
	LOC107829718	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1704 aa)
	LOC107831705	Uncharacterized protein LOC107831705. (495 aa)
	ubc2-1	Ubiquitin-conjugating enzyme E2 2 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	LOC107803861	Ubiquitin-conjugating enzyme E2 27-like; Belongs to the ubiquitin-conjugating enzyme family. (192 aa)

Your Current Organism:

Nicotiana tabacum

NCBI taxonomy Id: 4097
Other names: American tobacco, N. tabacum, Nicotiana tabacum L., common tobacco, tobacco

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Fni3	LOC107759736	A0A075EYQ4	A0A1S3X011	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	ubiquitin-60S ribosomal protein L40.	0.586
Fni3	LOC107760919	A0A075EYQ4	A0A1S3X3H9	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	Fatty acid desaturase 4, chloroplastic-like.	0.645
Fni3	LOC107761107	A0A075EYQ4	A0A1S3X4A8	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.615
Fni3	LOC107761315	A0A075EYQ4	A0A1S3X529	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2 4-like isoform X1; Belongs to the ubiquitin-conjugating enzyme family.	0.467
Fni3	LOC107762511	A0A075EYQ4	A0A1S3X8L6	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2 34-like.	0.551
Fni3	LOC107763564	A0A075EYQ4	A0A1S3XCA8	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase UPL3-like.	0.871
Fni3	LOC107766185	A0A075EYQ4	A0A1S3XKG1	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	E3 ubiquitin protein ligase.	0.480
Fni3	LOC107766688	A0A075EYQ4	A0A1S3XM54	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2 32-like.	0.448
Fni3	LOC107767217	A0A075EYQ4	A0A1S3XNS7	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	E3 ubiquitin-protein ligase UPL3.	0.871
Fni3	LOC107767426	A0A075EYQ4	A0A1S3XQG6	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	F-box protein At5g07610-like.	0.586
Fni3	LOC107767854	A0A075EYQ4	A0A1S3XRD6	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	ubiquitin-60S ribosomal protein L40.	0.586
Fni3	LOC107767930	A0A075EYQ4	A0A1S3XRF1	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2 7-like; Belongs to the ubiquitin-conjugating enzyme family.	0.423
Fni3	LOC107769260	A0A075EYQ4	A0A1S3XVQ1	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	Polyubiquitin 11.	0.422
Fni3	LOC107769653	A0A075EYQ4	A0A1S3XWX3	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein LOC107769653 isoform X1.	0.545
Fni3	LOC107775245	A0A075EYQ4	A0A1S3YDY3	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2 34-like.	0.551
Fni3	LOC107775515	A0A075EYQ4	A0A1S3YF09	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	E3 ubiquitin-protein ligase KEG-like.	0.866
Fni3	LOC107775817	A0A075EYQ4	A0A1S3YFV4	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2 2-like isoform X1.	0.462
Fni3	LOC107775987	A0A075EYQ4	A0A1S3YG75	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2 32-like.	0.448
Fni3	LOC107782760	A0A075EYQ4	A0A1S3Z465	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	E3 ubiquitin-protein ligase UPL3-like.	0.871
Fni3	LOC107783068	A0A075EYQ4	A0A1S3Z5N7	Ubiquitin-conjugating enzyme E2 35-like protein; Belongs to the ubiquitin-conjugating enzyme family.	E3 ubiquitin protein ligase.	0.480