15 items (Nicotiana tabacum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107761272	Protein ALWAYS EARLY 3-like isoform X1. (1138 aa)
	LOC107766447	Transcription factor E2FC-like. (378 aa)
	LOC107770785	Transcription factor-like protein DPB isoform X1; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family. (345 aa)
	LOC107775071	Uncharacterized protein LOC107775071. (279 aa)
	LOC107777437	Retinoblastoma-related protein 1 isoform X1. (1002 aa)
	LOC107801954	Retinoblastoma-related protein 1-like. (850 aa)
	LOC107804732	Transcription factor-like protein DPB isoform X1; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family. (345 aa)
	LOC107805661	Protein tesmin/TSO1-like CXC 5. (596 aa)
	LOC107808192	Protein ALWAYS EARLY 3-like. (1137 aa)
	LOC107810296	Protein ALWAYS EARLY 3-like. (285 aa)
	LOC107810295	Protein ALWAYS EARLY 3-like. (80 aa)
	LOC107816179	Transcription factor E2FA-like. (348 aa)
	LOC107816762	Transcription factor E2FA-like. (484 aa)
	LOC107828303	WD-40 repeat-containing protein MSI2-like. (403 aa)
	RB1	Retinoblastoma-related protein 1; Regulator of biological processes that recruits a histone deacetylase to control gene transcription. May play a role in the entry into mitosis, negatively regulating the cell proliferation. Formation of stable complexes with geminiviridae replication-associated proteins may create a cellular environment which favors viral DNA replication (By similarity); Belongs to the retinoblastoma protein (RB) family. (961 aa)

Your Current Organism:

Nicotiana tabacum

NCBI taxonomy Id: 4097
Other names: American tobacco, N. tabacum, Nicotiana tabacum L., common tobacco, tobacco

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC107761272	LOC107766447	A0A1S3X518	A0A1S3XL48	Protein ALWAYS EARLY 3-like isoform X1.	Transcription factor E2FC-like.	0.821
LOC107761272	LOC107770785	A0A1S3X518	A0A1S3Y0J8	Protein ALWAYS EARLY 3-like isoform X1.	Transcription factor-like protein DPB isoform X1; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family.	0.883
LOC107761272	LOC107775071	A0A1S3X518	A0A1S3YDL8	Protein ALWAYS EARLY 3-like isoform X1.	Uncharacterized protein LOC107775071.	0.804
LOC107761272	LOC107777437	A0A1S3X518	A0A1S3YL29	Protein ALWAYS EARLY 3-like isoform X1.	Retinoblastoma-related protein 1 isoform X1.	0.950
LOC107761272	LOC107801954	A0A1S3X518	A0A1S4AW80	Protein ALWAYS EARLY 3-like isoform X1.	Retinoblastoma-related protein 1-like.	0.950
LOC107761272	LOC107804732	A0A1S3X518	A0A1S4B5T6	Protein ALWAYS EARLY 3-like isoform X1.	Transcription factor-like protein DPB isoform X1; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family.	0.883
LOC107761272	LOC107805661	A0A1S3X518	A0A1S4B8G5	Protein ALWAYS EARLY 3-like isoform X1.	Protein tesmin/TSO1-like CXC 5.	0.804
LOC107761272	LOC107816179	A0A1S3X518	A0A1S4C7X9	Protein ALWAYS EARLY 3-like isoform X1.	Transcription factor E2FA-like.	0.821
LOC107761272	LOC107816762	A0A1S3X518	A0A1S4C9R9	Protein ALWAYS EARLY 3-like isoform X1.	Transcription factor E2FA-like.	0.821
LOC107761272	LOC107828303	A0A1S3X518	A0A1S4DCA1	Protein ALWAYS EARLY 3-like isoform X1.	WD-40 repeat-containing protein MSI2-like.	0.883
LOC107761272	RB1	A0A1S3X518	Q9SXN6	Protein ALWAYS EARLY 3-like isoform X1.	Retinoblastoma-related protein 1; Regulator of biological processes that recruits a histone deacetylase to control gene transcription. May play a role in the entry into mitosis, negatively regulating the cell proliferation. Formation of stable complexes with geminiviridae replication-associated proteins may create a cellular environment which favors viral DNA replication (By similarity); Belongs to the retinoblastoma protein (RB) family.	0.950
LOC107766447	LOC107761272	A0A1S3XL48	A0A1S3X518	Transcription factor E2FC-like.	Protein ALWAYS EARLY 3-like isoform X1.	0.821
LOC107766447	LOC107770785	A0A1S3XL48	A0A1S3Y0J8	Transcription factor E2FC-like.	Transcription factor-like protein DPB isoform X1; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family.	0.977
LOC107766447	LOC107775071	A0A1S3XL48	A0A1S3YDL8	Transcription factor E2FC-like.	Uncharacterized protein LOC107775071.	0.545
LOC107766447	LOC107777437	A0A1S3XL48	A0A1S3YL29	Transcription factor E2FC-like.	Retinoblastoma-related protein 1 isoform X1.	0.952
LOC107766447	LOC107801954	A0A1S3XL48	A0A1S4AW80	Transcription factor E2FC-like.	Retinoblastoma-related protein 1-like.	0.952
LOC107766447	LOC107804732	A0A1S3XL48	A0A1S4B5T6	Transcription factor E2FC-like.	Transcription factor-like protein DPB isoform X1; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family.	0.977
LOC107766447	LOC107805661	A0A1S3XL48	A0A1S4B8G5	Transcription factor E2FC-like.	Protein tesmin/TSO1-like CXC 5.	0.545
LOC107766447	LOC107808192	A0A1S3XL48	A0A1S4BH11	Transcription factor E2FC-like.	Protein ALWAYS EARLY 3-like.	0.821
LOC107766447	LOC107810295	A0A1S3XL48	A0A1S4BNW9	Transcription factor E2FC-like.	Protein ALWAYS EARLY 3-like.	0.821