(5 nodes) Protein neddylation network (Periophthalmus magnuspinnatus)

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Your Input:
	ENSPMGP00000012948	DCN1-like protein. (178 aa)
	ENSPMGP00000017027	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (505 aa)
	ENSPMGP00000018230	Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family. (135 aa)
	UBA3	Ubiquitin like modifier activating enzyme 3. (436 aa)
	ENSPMGP00000023295	Ubiquitin-like domain-containing protein. (90 aa)

Your Current Organism:

Periophthalmus magnuspinnatus

NCBI taxonomy Id: 409849
Other names: P. magnuspinnatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPMGP00000012948	ENSPMGP00000017027	ENSPMGP00000012948	ENSPMGP00000017027	DCN1-like protein.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	0.775
ENSPMGP00000012948	ENSPMGP00000018230	ENSPMGP00000012948	ENSPMGP00000018230	DCN1-like protein.	Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family.	0.938
ENSPMGP00000012948	ENSPMGP00000023295	ENSPMGP00000012948	ENSPMGP00000023295	DCN1-like protein.	Ubiquitin-like domain-containing protein.	0.912
ENSPMGP00000012948	UBA3	ENSPMGP00000012948	ENSPMGP00000019145	DCN1-like protein.	Ubiquitin like modifier activating enzyme 3.	0.822
ENSPMGP00000017027	ENSPMGP00000012948	ENSPMGP00000017027	ENSPMGP00000012948	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	DCN1-like protein.	0.775
ENSPMGP00000017027	ENSPMGP00000018230	ENSPMGP00000017027	ENSPMGP00000018230	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family.	0.975
ENSPMGP00000017027	ENSPMGP00000023295	ENSPMGP00000017027	ENSPMGP00000023295	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Ubiquitin-like domain-containing protein.	0.983
ENSPMGP00000017027	UBA3	ENSPMGP00000017027	ENSPMGP00000019145	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Ubiquitin like modifier activating enzyme 3.	0.999
ENSPMGP00000018230	ENSPMGP00000012948	ENSPMGP00000018230	ENSPMGP00000012948	Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family.	DCN1-like protein.	0.938
ENSPMGP00000018230	ENSPMGP00000017027	ENSPMGP00000018230	ENSPMGP00000017027	Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	0.975
ENSPMGP00000018230	ENSPMGP00000023295	ENSPMGP00000018230	ENSPMGP00000023295	Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-like domain-containing protein.	0.950
ENSPMGP00000018230	UBA3	ENSPMGP00000018230	ENSPMGP00000019145	Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin like modifier activating enzyme 3.	0.979
ENSPMGP00000023295	ENSPMGP00000012948	ENSPMGP00000023295	ENSPMGP00000012948	Ubiquitin-like domain-containing protein.	DCN1-like protein.	0.912
ENSPMGP00000023295	ENSPMGP00000017027	ENSPMGP00000023295	ENSPMGP00000017027	Ubiquitin-like domain-containing protein.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	0.983
ENSPMGP00000023295	ENSPMGP00000018230	ENSPMGP00000023295	ENSPMGP00000018230	Ubiquitin-like domain-containing protein.	Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family.	0.950
ENSPMGP00000023295	UBA3	ENSPMGP00000023295	ENSPMGP00000019145	Ubiquitin-like domain-containing protein.	Ubiquitin like modifier activating enzyme 3.	0.982
UBA3	ENSPMGP00000012948	ENSPMGP00000019145	ENSPMGP00000012948	Ubiquitin like modifier activating enzyme 3.	DCN1-like protein.	0.822
UBA3	ENSPMGP00000017027	ENSPMGP00000019145	ENSPMGP00000017027	Ubiquitin like modifier activating enzyme 3.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	0.999
UBA3	ENSPMGP00000018230	ENSPMGP00000019145	ENSPMGP00000018230	Ubiquitin like modifier activating enzyme 3.	Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family.	0.979
UBA3	ENSPMGP00000023295	ENSPMGP00000019145	ENSPMGP00000023295	Ubiquitin like modifier activating enzyme 3.	Ubiquitin-like domain-containing protein.	0.982