node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSPMGP00000002432 | ENSPMGP00000005583 | ENSPMGP00000002432 | ENSPMGP00000005583 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | 0.769 |
ENSPMGP00000002432 | ENSPMGP00000005679 | ENSPMGP00000002432 | ENSPMGP00000005679 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | ATG16 autophagy related 16-like 1 (S. cerevisiae). | 0.582 |
ENSPMGP00000002432 | ENSPMGP00000008914 | ENSPMGP00000002432 | ENSPMGP00000008914 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | GSAP-16 domain-containing protein. | 0.404 |
ENSPMGP00000002432 | ENSPMGP00000009645 | ENSPMGP00000002432 | ENSPMGP00000009645 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | NBR1 autophagy cargo receptor b. | 0.502 |
ENSPMGP00000002432 | ENSPMGP00000012966 | ENSPMGP00000002432 | ENSPMGP00000012966 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | 0.836 |
ENSPMGP00000002432 | ENSPMGP00000015048 | ENSPMGP00000002432 | ENSPMGP00000015048 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | Microtubule-associated protein 1 light chain 3 alpha. | 0.974 |
ENSPMGP00000002432 | ENSPMGP00000019321 | ENSPMGP00000002432 | ENSPMGP00000019321 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | Autophagy-related protein 3. | 0.857 |
ENSPMGP00000002432 | ENSPMGP00000021842 | ENSPMGP00000002432 | ENSPMGP00000021842 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | Microtubule-associated protein 1 light chain 3 beta. | 0.974 |
ENSPMGP00000002432 | ENSPMGP00000022363 | ENSPMGP00000002432 | ENSPMGP00000022363 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | Zgc:92606. | 0.957 |
ENSPMGP00000002432 | ENSPMGP00000022372 | ENSPMGP00000002432 | ENSPMGP00000022372 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | Microtubule-associated protein 1 light chain 3 gamma, like. | 0.883 |
ENSPMGP00000002432 | ENSPMGP00000023583 | ENSPMGP00000002432 | ENSPMGP00000023583 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | Autophagy protein 5; Involved in autophagic vesicle formation. | 0.659 |
ENSPMGP00000002432 | ENSPMGP00000023674 | ENSPMGP00000002432 | ENSPMGP00000023674 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | NBR1 autophagy cargo receptor a. | 0.502 |
ENSPMGP00000002432 | ENSPMGP00000023685 | ENSPMGP00000002432 | ENSPMGP00000023685 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | 0.824 |
ENSPMGP00000002432 | ENSPMGP00000027701 | ENSPMGP00000002432 | ENSPMGP00000027701 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | GABA(A) receptor-associated protein b. | 0.995 |
ENSPMGP00000002432 | ENSPMGP00000028482 | ENSPMGP00000002432 | ENSPMGP00000028482 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | Unc-51 like autophagy activating kinase 1a. | 0.936 |
ENSPMGP00000002432 | ENSPMGP00000028496 | ENSPMGP00000002432 | ENSPMGP00000028496 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | 0.711 |
ENSPMGP00000002432 | GABARAPL2 | ENSPMGP00000002432 | ENSPMGP00000027417 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | GABA type A receptor associated protein like 2. | 0.995 |
ENSPMGP00000005583 | ENSPMGP00000002432 | ENSPMGP00000005583 | ENSPMGP00000002432 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. | 0.769 |
ENSPMGP00000005583 | ENSPMGP00000005679 | ENSPMGP00000005583 | ENSPMGP00000005679 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | ATG16 autophagy related 16-like 1 (S. cerevisiae). | 0.851 |
ENSPMGP00000005583 | ENSPMGP00000008914 | ENSPMGP00000005583 | ENSPMGP00000008914 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | GSAP-16 domain-containing protein. | 0.674 |