(12 nodes) Autophagy, and Next to BRCA1, central domain network (Periophthalmus magnuspinnatus)

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Known Interactions

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Predicted Interactions

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Your Input:
	ENSPMGP00000005583	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (658 aa)
	ENSPMGP00000005679	ATG16 autophagy related 16-like 1 (S. cerevisiae). (561 aa)
	ENSPMGP00000008914	GSAP-16 domain-containing protein. (122 aa)
	ENSPMGP00000009645	NBR1 autophagy cargo receptor b. (717 aa)
	ENSPMGP00000015048	Microtubule-associated protein 1 light chain 3 alpha. (121 aa)
	ENSPMGP00000019321	Autophagy-related protein 3. (288 aa)
	ENSPMGP00000021842	Microtubule-associated protein 1 light chain 3 beta. (126 aa)
	ENSPMGP00000022372	Microtubule-associated protein 1 light chain 3 gamma, like. (123 aa)
	ENSPMGP00000023583	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	ENSPMGP00000023674	NBR1 autophagy cargo receptor a. (571 aa)
	ENSPMGP00000027701	GABA(A) receptor-associated protein b. (161 aa)
	ENSPMGP00000028496	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (105 aa)

Your Current Organism:

Periophthalmus magnuspinnatus

NCBI taxonomy Id: 409849
Other names: P. magnuspinnatus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
ENSPMGP00000005583	ENSPMGP00000005679	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	ATG16 autophagy related 16-like 1 (S. cerevisiae).	0.851
ENSPMGP00000005583	ENSPMGP00000008914	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	GSAP-16 domain-containing protein.	0.674
ENSPMGP00000005583	ENSPMGP00000009645	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	NBR1 autophagy cargo receptor b.	0.702
ENSPMGP00000005583	ENSPMGP00000015048	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Microtubule-associated protein 1 light chain 3 alpha.	0.960
ENSPMGP00000005583	ENSPMGP00000019321	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Autophagy-related protein 3.	0.999
ENSPMGP00000005583	ENSPMGP00000021842	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Microtubule-associated protein 1 light chain 3 beta.	0.960
ENSPMGP00000005583	ENSPMGP00000022372	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Microtubule-associated protein 1 light chain 3 gamma, like.	0.939
ENSPMGP00000005583	ENSPMGP00000023583	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Autophagy protein 5; Involved in autophagic vesicle formation.	0.953
ENSPMGP00000005583	ENSPMGP00000023674	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	NBR1 autophagy cargo receptor a.	0.702
ENSPMGP00000005583	ENSPMGP00000027701	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	GABA(A) receptor-associated protein b.	0.993
ENSPMGP00000005583	ENSPMGP00000028496	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
ENSPMGP00000005679	ENSPMGP00000005583	ATG16 autophagy related 16-like 1 (S. cerevisiae).	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.851
ENSPMGP00000005679	ENSPMGP00000008914	ATG16 autophagy related 16-like 1 (S. cerevisiae).	GSAP-16 domain-containing protein.	0.646
ENSPMGP00000005679	ENSPMGP00000009645	ATG16 autophagy related 16-like 1 (S. cerevisiae).	NBR1 autophagy cargo receptor b.	0.707
ENSPMGP00000005679	ENSPMGP00000015048	ATG16 autophagy related 16-like 1 (S. cerevisiae).	Microtubule-associated protein 1 light chain 3 alpha.	0.851
ENSPMGP00000005679	ENSPMGP00000019321	ATG16 autophagy related 16-like 1 (S. cerevisiae).	Autophagy-related protein 3.	0.993
ENSPMGP00000005679	ENSPMGP00000021842	ATG16 autophagy related 16-like 1 (S. cerevisiae).	Microtubule-associated protein 1 light chain 3 beta.	0.851
ENSPMGP00000005679	ENSPMGP00000022372	ATG16 autophagy related 16-like 1 (S. cerevisiae).	Microtubule-associated protein 1 light chain 3 gamma, like.	0.810
ENSPMGP00000005679	ENSPMGP00000023583	ATG16 autophagy related 16-like 1 (S. cerevisiae).	Autophagy protein 5; Involved in autophagic vesicle formation.	0.998
ENSPMGP00000005679	ENSPMGP00000023674	ATG16 autophagy related 16-like 1 (S. cerevisiae).	NBR1 autophagy cargo receptor a.	0.707