(62 nodes) Ribosomal large subunit biogenesis network (Periophthalmus magnuspinnatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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textmining

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protein homology

Your Input:
	NOP2	NOP2 nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (726 aa)
	ENSPMGP00000027588	Ribosomal L1 domain containing 1. (294 aa)
	ENSPMGP00000027601	Uncharacterized protein. (143 aa)
	ENSPMGP00000028556	Brix domain containing 2. (320 aa)
	ENSPMGP00000028972	C19h1orf109 homolog (H. sapiens). (211 aa)
	ENSPMGP00000029300	Spermatogenesis associated 5-like 1. (728 aa)
	ENSPMGP00000029519	General transcription factor IIIA, b. (259 aa)
	BOP1	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (688 aa)
	ENSPMGP00000011414	NOC2-like nucleolar associated transcriptional repressor. (732 aa)
	ENSPMGP00000011255	PAK1 interacting protein 1. (357 aa)
	ENSPMGP00000011183	Zinc finger protein 622. (447 aa)
	ENSPMGP00000010862	Ribosomal protein L7. (245 aa)
	SPATA5	Spermatogenesis associated 5; Belongs to the AAA ATPase family. (674 aa)
	ENSPMGP00000009990	Nucleophosmin 1b. (159 aa)
	ENSPMGP00000014289	Nucleophosmin 1a. (272 aa)
	MALSU1	Mitochondrial assembly of ribosomal large subunit 1. (234 aa)
	ENSPMGP00000014783	Nuclear VCP like; Belongs to the AAA ATPase family. (400 aa)
	EIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (169 aa)
	ENSPMGP00000015815	FtsJ RNA 2'-O-methyltransferase 3. (729 aa)
	ENSPMGP00000015880	RAP domain-containing protein. (554 aa)
	ENSPMGP00000016068	Zinc finger, HIT-type containing 2. (529 aa)
	ENSPMGP00000016382	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (225 aa)
	ENSPMGP00000016980	Ribosomal protein L10. (179 aa)
	ENSPMGP00000018042	Uncharacterized protein. (422 aa)
	WDR12	Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (400 aa)
	RPL5-2	Ribosomal protein L5b. (301 aa)
	ENSPMGP00000020590	Nucleolar protein interacting with the FHA domain of MKI67. (261 aa)
	ENSPMGP00000020719	NSA2 ribosome biogenesis homolog (S. cerevisiae). (262 aa)
	ENSPMGP00000021506	Ribosomal protein L14. (138 aa)
	ENSPMGP00000021822	Uncharacterized protein. (118 aa)
	ENSPMGP00000022443	Ribosomal RNA processing 15 homolog. (240 aa)
	ENSPMGP00000022762	Ribosomal protein L6. (264 aa)
	PES1	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (551 aa)
	ENSPMGP00000024034	Helicase ATP-binding domain-containing protein. (306 aa)
	ENSPMGP00000024383	Ribosomal protein L35. (122 aa)
	ENSPMGP00000026746	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (453 aa)
	ENSPMGP00000009538	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28. (562 aa)
	ENSPMGP00000009130	Notchless homolog 1 (Drosophila). (464 aa)
	ENSPMGP00000009011	Zinc finger, HIT-type containing 3. (120 aa)
	ENSPMGP00000008969	Ribosomal protein L26. (145 aa)
	ENSPMGP00000008709	HEAT repeat containing 3. (676 aa)
	ENSPMGP00000008653	RNA helicase. (602 aa)
	ENSPMGP00000007803	TNF receptor-associated factor 7. (596 aa)
	ENSPMGP00000007143	Ribosomal L24 domain containing 1. (186 aa)
	ENSPMGP00000006491	Ribosomal protein L23a; Belongs to the universal ribosomal protein uL23 family. (155 aa)
	ENSPMGP00000006007	LTO1 maturation factor of ABCE1. (147 aa)
	ENSPMGP00000004929	Protein MAK16 homolog; Belongs to the MAK16 family. (295 aa)
	CINP	Cyclin dependent kinase 2 interacting protein. (207 aa)
	ENSPMGP00000004738	Mitochondrial ribosomal protein L1. (327 aa)
	ENSPMGP00000004679	Mitochondrial ribosomal protein L20; Belongs to the bacterial ribosomal protein bL20 family. (149 aa)
	ENSPMGP00000004048	WD repeat domain 74. (303 aa)
	ENSPMGP00000004029	NOP16 nucleolar protein homolog (yeast). (172 aa)
	ENSPMGP00000003376	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (163 aa)
	ENSPMGP00000002636	Ribosomal protein L7-like 1. (252 aa)
	ENSPMGP00000002596	Si:dkey-208k4.2. (371 aa)
	ENSPMGP00000001654	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (610 aa)
	ENSPMGP00000000905	Mitochondrial rRNA methyltransferase 2. (239 aa)
	ENSPMGP00000000326	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (122 aa)
	ZNHIT6	Zinc finger HIT-type containing 6. (282 aa)
	ENSPMGP00000012898	EBNA1 binding protein 2. (318 aa)
	RPL5	Ribosomal protein L5. (281 aa)
	ENSPMGP00000013900	Ribosome production factor 1 homolog. (356 aa)

Your Current Organism:

Periophthalmus magnuspinnatus

NCBI taxonomy Id: 409849
Other names: P. magnuspinnatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BOP1	EIF6	ENSPMGP00000029817	ENSPMGP00000015046	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	0.962
BOP1	ENSPMGP00000000326	ENSPMGP00000029817	ENSPMGP00000000326	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.	0.826
BOP1	ENSPMGP00000000905	ENSPMGP00000029817	ENSPMGP00000000905	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Mitochondrial rRNA methyltransferase 2.	0.945
BOP1	ENSPMGP00000001654	ENSPMGP00000029817	ENSPMGP00000001654	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.992
BOP1	ENSPMGP00000002636	ENSPMGP00000029817	ENSPMGP00000002636	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal protein L7-like 1.	0.984
BOP1	ENSPMGP00000003376	ENSPMGP00000029817	ENSPMGP00000003376	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.933
BOP1	ENSPMGP00000004048	ENSPMGP00000029817	ENSPMGP00000004048	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD repeat domain 74.	0.994
BOP1	ENSPMGP00000004738	ENSPMGP00000029817	ENSPMGP00000004738	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Mitochondrial ribosomal protein L1.	0.634
BOP1	ENSPMGP00000004929	ENSPMGP00000029817	ENSPMGP00000004929	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Protein MAK16 homolog; Belongs to the MAK16 family.	0.964
BOP1	ENSPMGP00000006491	ENSPMGP00000029817	ENSPMGP00000006491	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal protein L23a; Belongs to the universal ribosomal protein uL23 family.	0.951
BOP1	ENSPMGP00000007143	ENSPMGP00000029817	ENSPMGP00000007143	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal L24 domain containing 1.	0.986
BOP1	ENSPMGP00000008653	ENSPMGP00000029817	ENSPMGP00000008653	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RNA helicase.	0.995
BOP1	ENSPMGP00000008969	ENSPMGP00000029817	ENSPMGP00000008969	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal protein L26.	0.876
BOP1	ENSPMGP00000009130	ENSPMGP00000029817	ENSPMGP00000009130	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Notchless homolog 1 (Drosophila).	0.913
BOP1	ENSPMGP00000009538	ENSPMGP00000029817	ENSPMGP00000009538	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28.	0.911
BOP1	ENSPMGP00000009990	ENSPMGP00000029817	ENSPMGP00000009990	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleophosmin 1b.	0.619
BOP1	ENSPMGP00000010862	ENSPMGP00000029817	ENSPMGP00000010862	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal protein L7.	0.984
BOP1	ENSPMGP00000011183	ENSPMGP00000029817	ENSPMGP00000011183	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Zinc finger protein 622.	0.426
BOP1	ENSPMGP00000011255	ENSPMGP00000029817	ENSPMGP00000011255	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	PAK1 interacting protein 1.	0.771
BOP1	ENSPMGP00000011414	ENSPMGP00000029817	ENSPMGP00000011414	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	NOC2-like nucleolar associated transcriptional repressor.	0.994