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LIAS | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (381 aa) | ||||
ENSPMGP00000000232 | Excision repair cross-complementation group 2. (659 aa) | ||||
ENSPMGP00000000981 | INO80 complex subunit Da. (949 aa) | ||||
NUBP1 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (383 aa) | ||||
ENSPMGP00000001519 | DNA replication helicase/nuclease 2. (918 aa) | ||||
ENSPMGP00000001523 | Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (65 aa) | ||||
ENSPMGP00000002116 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (452 aa) | ||||
ENSPMGP00000004675 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (259 aa) | ||||
ENSPMGP00000004769 | Aconitase 2, mitochondrial. (765 aa) | ||||
ENSPMGP00000005030 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). (698 aa) | ||||
NUBP2 | Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (267 aa) | ||||
ENSPMGP00000007381 | Molybdenum cofactor synthesis 1. (369 aa) | ||||
ENSPMGP00000007825 | MTTase N-terminal domain-containing protein. (188 aa) | ||||
ENSPMGP00000009101 | NADH:ubiquinone oxidoreductase core subunit S8a. (193 aa) | ||||
ENSPMGP00000009518 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11. (829 aa) | ||||
ENSPMGP00000010347 | Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (421 aa) | ||||
ENSPMGP00000010348 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (495 aa) | ||||
ENSPMGP00000013081 | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (508 aa) | ||||
ENSPMGP00000013504 | 2Fe-2S ferredoxin-type domain-containing protein. (91 aa) | ||||
ENSPMGP00000013507 | NADH:ubiquinone oxidoreductase core subunit S1. (263 aa) | ||||
ENSPMGP00000014108 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (409 aa) | ||||
ENSPMGP00000014155 | Iron-sulfur cluster assembly 2. (150 aa) | ||||
ENSPMGP00000014596 | NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae). (274 aa) | ||||
ENSPMGP00000015007 | Uncharacterized protein; Belongs to the complex I 49 kDa subunit family. (447 aa) | ||||
SDHB | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (274 aa) | ||||
ENSPMGP00000016780 | BRCA1 interacting protein C-terminal helicase 1. (864 aa) | ||||
ENSPMGP00000016820 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (596 aa) | ||||
ENSPMGP00000017287 | Uncharacterized protein. (185 aa) | ||||
ENSPMGP00000017892 | NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (464 aa) | ||||
ENSPMGP00000018940 | Helicase ATP-binding domain-containing protein. (107 aa) | ||||
ENSPMGP00000019186 | DNA polymerase. (1034 aa) | ||||
ENSPMGP00000020009 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (538 aa) | ||||
NTHL1 | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (336 aa) | ||||
ENSPMGP00000020419 | Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (66 aa) | ||||
ENSPMGP00000020774 | Iron-responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. (962 aa) | ||||
CIAPIN1 | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (295 aa) | ||||
ENSPMGP00000022930 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (937 aa) | ||||
ENSPMGP00000023441 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (310 aa) | ||||
ENSPMGP00000023442 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (328 aa) | ||||
ENSPMGP00000025427 | NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (228 aa) | ||||
ENSPMGP00000025453 | Nuclear prelamin A recognition factor-like; Belongs to the NARF family. (448 aa) | ||||
ENSPMGP00000025651 | Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. (894 aa) | ||||
ENSPMGP00000025978 | Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (64 aa) | ||||
ENSPMGP00000027034 | Oxidored_q6 domain-containing protein; Belongs to the complex I 20 kDa subunit family. (241 aa) | ||||
ENSPMGP00000027988 | CDK5 regulatory subunit associated protein 1-like 1. (543 aa) | ||||
ENSPMGP00000028273 | Nucleotide binding protein-like. (309 aa) | ||||
ENSPMGP00000028409 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. (489 aa) | ||||
RTEL1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1105 aa) |