(57 nodes) Regulation of lipid metabolism by PPARalpha network (Periophthalmus magnuspinnatus)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	ENSPMGP00000029637	SIN3 transcription regulator family member Aa. (1266 aa)
	ENSPMGP00000000268	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1688 aa)
	MED11	Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (119 aa)
	MED18	Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (209 aa)
	ENSPMGP00000001559	Family with sequence similarity 120B. (637 aa)
	ENSPMGP00000002169	Nuclear transcription factor Y, gamma. (306 aa)
	ENSPMGP00000002618	Four and a half LIM domains 3a. (279 aa)
	ENSPMGP00000002691	MAP7 domain containing 1a. (580 aa)
	ENSPMGP00000002699	Uncharacterized protein. (766 aa)
	ENSPMGP00000004149	Nuclear respiratory factor 1. (506 aa)
	ENSPMGP00000004896	Metal-regulatory transcription factor 1. (738 aa)
	ENSPMGP00000005522	Tumor necrosis factor receptor superfamily, member 21. (625 aa)
	ENSPMGP00000006009	Transducin beta like 1 X-linked. (512 aa)
	ENSPMGP00000006049	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (603 aa)
	ENSPMGP00000006415	CREB binding protein a. (2183 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha b. (436 aa)
	ENSPMGP00000007632	SIN3 transcription regulator family member B. (1080 aa)
	ENSPMGP00000007715	Uncharacterized protein. (192 aa)
	ENSPMGP00000007969	Ankyrin repeat domain 1a (cardiac muscle). (288 aa)
	ENSPMGP00000008402	Nucleic_acid_bd domain-containing protein. (186 aa)
	ENSPMGP00000009572	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (93 aa)
	ENSPMGP00000010616	Uncharacterized protein. (64 aa)
	HDAC3	Histone deacetylase 3. (353 aa)
	ENSPMGP00000011277	Transducin (beta)-like 1 X-linked receptor 1b. (509 aa)
	ENSPMGP00000011683	Mediator complex subunit 29. (177 aa)
	ENSPMGP00000011773	Nuclear receptor coactivator 2. (1389 aa)
	ENSPMGP00000012825	Four and a half LIM domains 2b. (279 aa)
	ENSPMGP00000013779	CARM1 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (420 aa)
	MED19	Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (243 aa)
	ENSPMGP00000015267	Nuclear transcription factor Y, beta a. (218 aa)
	ENSPMGP00000015448	ANK_REP_REGION domain-containing protein. (321 aa)
	ENSPMGP00000015516	LYN proto-oncogene, Src family tyrosine kinase. (607 aa)
	ENSPMGP00000015527	Uncharacterized protein. (359 aa)
	ENSPMGP00000015706	Four and a half LIM domains 5. (275 aa)
	ENSPMGP00000017473	Peroxisome proliferator-activated receptor gamma, coactivator 1 beta. (739 aa)
	ENSPMGP00000017544	Grainyhead-like transcription factor 1. (612 aa)
	MED9	Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (99 aa)
	FABP1	Fatty acid binding protein 1. (127 aa)
	ENSPMGP00000021317	Fatty acid binding protein 1. (127 aa)
	ENSPMGP00000021497	TFIIS N-terminal domain-containing protein. (562 aa)
	ENSPMGP00000022138	MAP7 domain containing 3. (517 aa)
	ENSPMGP00000022562	Nuclear receptor corepressor 1. (2249 aa)
	ENSPMGP00000023742	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (855 aa)
	ENSPMGP00000025117	Nuclear receptor coactivator 1. (1344 aa)
	ENSPMGP00000025175	Ankyrin repeat domain 2 (stretch responsive muscle). (277 aa)
	ENSPMGP00000026235	SIN3 transcription regulator family member Ab. (1256 aa)
	ENSPMGP00000026595	Uncharacterized protein. (466 aa)
	ENSPMGP00000028127	Uncharacterized protein. (279 aa)
	ENSPMGP00000028129	Uncharacterized protein. (197 aa)
	ENSPMGP00000028350	CP2 domain-containing protein. (584 aa)
	ENSPMGP00000028430	Nuclear receptor corepressor 2. (1874 aa)
	ENSPMGP00000028722	Grainyhead-like transcription factor 2b. (615 aa)
	ENSPMGP00000029066	Uncharacterized protein. (517 aa)
	ENSPMGP00000029100	MAP7 domain containing 1. (557 aa)
	ENSPMGP00000029103	Thyroid hormone receptor associated protein 3b. (736 aa)
	ENSPMGP00000029109	Uncharacterized protein. (469 aa)
	ENSPMGP00000029603	Nuclear transcription factor Y, alpha, like. (309 aa)

Your Current Organism:

Periophthalmus magnuspinnatus

NCBI taxonomy Id: 409849
Other names: P. magnuspinnatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPMGP00000000268	ENSPMGP00000001559	ENSPMGP00000000268	ENSPMGP00000001559	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Family with sequence similarity 120B.	0.531
ENSPMGP00000000268	ENSPMGP00000002691	ENSPMGP00000000268	ENSPMGP00000002691	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	MAP7 domain containing 1a.	0.496
ENSPMGP00000000268	ENSPMGP00000002699	ENSPMGP00000000268	ENSPMGP00000002699	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.557
ENSPMGP00000000268	ENSPMGP00000006009	ENSPMGP00000000268	ENSPMGP00000006009	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Transducin beta like 1 X-linked.	0.772
ENSPMGP00000000268	ENSPMGP00000006049	ENSPMGP00000000268	ENSPMGP00000006049	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.826
ENSPMGP00000000268	ENSPMGP00000006415	ENSPMGP00000000268	ENSPMGP00000006415	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	CREB binding protein a.	0.836
ENSPMGP00000000268	ENSPMGP00000007632	ENSPMGP00000000268	ENSPMGP00000007632	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	SIN3 transcription regulator family member B.	0.622
ENSPMGP00000000268	ENSPMGP00000008402	ENSPMGP00000000268	ENSPMGP00000008402	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nucleic_acid_bd domain-containing protein.	0.762
ENSPMGP00000000268	ENSPMGP00000009572	ENSPMGP00000000268	ENSPMGP00000009572	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.988
ENSPMGP00000000268	ENSPMGP00000010616	ENSPMGP00000000268	ENSPMGP00000010616	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.624
ENSPMGP00000000268	ENSPMGP00000011277	ENSPMGP00000000268	ENSPMGP00000011277	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Transducin (beta)-like 1 X-linked receptor 1b.	0.772
ENSPMGP00000000268	ENSPMGP00000011683	ENSPMGP00000000268	ENSPMGP00000011683	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator complex subunit 29.	0.994
ENSPMGP00000000268	ENSPMGP00000011773	ENSPMGP00000000268	ENSPMGP00000011773	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor coactivator 2.	0.807
ENSPMGP00000000268	ENSPMGP00000013779	ENSPMGP00000000268	ENSPMGP00000013779	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	CARM1 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.826
ENSPMGP00000000268	ENSPMGP00000015516	ENSPMGP00000000268	ENSPMGP00000015516	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	LYN proto-oncogene, Src family tyrosine kinase.	0.738
ENSPMGP00000000268	ENSPMGP00000015527	ENSPMGP00000000268	ENSPMGP00000015527	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.807
ENSPMGP00000000268	ENSPMGP00000021497	ENSPMGP00000000268	ENSPMGP00000021497	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	TFIIS N-terminal domain-containing protein.	0.982
ENSPMGP00000000268	ENSPMGP00000022138	ENSPMGP00000000268	ENSPMGP00000022138	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	MAP7 domain containing 3.	0.473
ENSPMGP00000000268	ENSPMGP00000022562	ENSPMGP00000000268	ENSPMGP00000022562	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor corepressor 1.	0.727
ENSPMGP00000000268	ENSPMGP00000023742	ENSPMGP00000000268	ENSPMGP00000023742	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.594