STRINGSTRING
RPA1 RPA1 ENSPMGP00000016967 ENSPMGP00000016967 ENSPMGP00000016603 ENSPMGP00000016603 ENSPMGP00000016599 ENSPMGP00000016599 HUS1 HUS1 ENSPMGP00000014113 ENSPMGP00000014113 ENSPMGP00000013512 ENSPMGP00000013512 ENSPMGP00000013336 ENSPMGP00000013336 RCBTB1 RCBTB1 ENSPMGP00000011905 ENSPMGP00000011905 ENSPMGP00000011646 ENSPMGP00000011646 ENSPMGP00000011645 ENSPMGP00000011645 ENSPMGP00000010557 ENSPMGP00000010557 ENSPMGP00000010440 ENSPMGP00000010440 ENSPMGP00000010071 ENSPMGP00000010071 ENSPMGP00000008014 ENSPMGP00000008014 ENSPMGP00000006737 ENSPMGP00000006737 ENSPMGP00000005554 ENSPMGP00000005554 ENSPMGP00000005337 ENSPMGP00000005337 ENSPMGP00000005322 ENSPMGP00000005322 ENSPMGP00000004772 ENSPMGP00000004772 ENSPMGP00000004508 ENSPMGP00000004508 ENSPMGP00000003957 ENSPMGP00000003957 ENSPMGP00000002858 ENSPMGP00000002858 ENSPMGP00000002437 ENSPMGP00000002437 ENSPMGP00000001519 ENSPMGP00000001519 ENSPMGP00000000209 ENSPMGP00000000209 ENSPMGP00000029368 ENSPMGP00000029368 ENSPMGP00000028552 ENSPMGP00000028552 ENSPMGP00000027589 ENSPMGP00000027589 ENSPMGP00000026544 ENSPMGP00000026544 ENSPMGP00000026408 ENSPMGP00000026408 ENSPMGP00000026072 ENSPMGP00000026072 ENSPMGP00000024916 ENSPMGP00000024916 ENSPMGP00000024148 ENSPMGP00000024148 ENSPMGP00000024084 ENSPMGP00000024084 ENSPMGP00000023519 ENSPMGP00000023519 ENSPMGP00000023182 ENSPMGP00000023182 ENSPMGP00000021944 ENSPMGP00000021944 ENSPMGP00000020400 ENSPMGP00000020400 ENSPMGP00000019587 ENSPMGP00000019587 ENSPMGP00000019369 ENSPMGP00000019369 ENSPMGP00000018716 ENSPMGP00000018716 ENSPMGP00000018529 ENSPMGP00000018529
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (587 aa)
ENSPMGP00000016967Ankyrin repeat domain 11. (2717 aa)
ENSPMGP00000016603ANK_REP_REGION domain-containing protein. (261 aa)
ENSPMGP00000016599BRCT domain-containing protein. (176 aa)
HUS1Checkpoint protein; Belongs to the HUS1 family. (275 aa)
ENSPMGP00000014113Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (568 aa)
ENSPMGP00000013512DNA topoisomerase II binding protein 1. (1436 aa)
ENSPMGP00000013336Tyrosine-protein kinase. (1096 aa)
RCBTB1Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (350 aa)
ENSPMGP00000011905RING-type domain-containing protein. (103 aa)
ENSPMGP00000011646Metallophos domain-containing protein. (104 aa)
ENSPMGP00000011645MRE11 homolog A, double strand break repair nuclease. (451 aa)
ENSPMGP00000010557Methionine sulfoxide reductase B1b. (383 aa)
ENSPMGP00000010440Cell cycle checkpoint control protein; Belongs to the rad9 family. (385 aa)
ENSPMGP00000010071RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (454 aa)
ENSPMGP00000008014ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (896 aa)
ENSPMGP00000006737RAD17 checkpoint clamp loader component. (472 aa)
ENSPMGP00000005554RecQ mediated genome instability 2. (149 aa)
ENSPMGP00000005337Replication protein A2. (280 aa)
ENSPMGP00000005322Uncharacterized protein. (141 aa)
ENSPMGP00000004772Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (571 aa)
ENSPMGP00000004508RAD9 checkpoint clamp component B. (183 aa)
ENSPMGP00000003957Replication factor C (activator 1) 2. (342 aa)
ENSPMGP00000002858Uncharacterized protein. (158 aa)
ENSPMGP00000002437Uncharacterized protein. (283 aa)
ENSPMGP00000001519DNA replication helicase/nuclease 2. (918 aa)
ENSPMGP00000000209Cell division cycle associated 7a. (399 aa)
ENSPMGP00000029368Replication factor C (activator 1) 3. (270 aa)
ENSPMGP00000028552RAD1 homolog (S. pombe). (281 aa)
ENSPMGP00000027589RAD52 homolog, DNA repair protein. (390 aa)
ENSPMGP00000026544RecQ helicase-like 4. (1317 aa)
ENSPMGP00000026408Replication protein A3. (122 aa)
ENSPMGP00000026072Exonuclease 3'-5' domain containing 2. (626 aa)
ENSPMGP00000024916Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (548 aa)
ENSPMGP00000024148RAD50 homolog, double strand break repair protein. (1270 aa)
ENSPMGP00000024084Exonuclease 1. (559 aa)
ENSPMGP00000023519Uncharacterized protein. (465 aa)
ENSPMGP00000023182DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (340 aa)
ENSPMGP00000021944DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (929 aa)
ENSPMGP00000020400Replication factor C (activator 1) 4. (358 aa)
ENSPMGP00000019587ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2554 aa)
ENSPMGP00000019369ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2737 aa)
ENSPMGP00000018716Tudor domain containing 3. (757 aa)
ENSPMGP00000018529Replication factor C (activator 1) 5. (336 aa)
Your Current Organism:
Periophthalmus magnuspinnatus
NCBI taxonomy Id: 409849
Other names: P. magnuspinnatus
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