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| | ENSPMGP00000000209 | Cell division cycle associated 7a. (399 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (587 aa) |
| | ENSPMGP00000000945 | Wee1-like protein kinase. (496 aa) |
| | ENSPMGP00000001504 | Uncharacterized protein; Belongs to the histone H2A family. (245 aa) |
| | ENSPMGP00000001519 | DNA replication helicase/nuclease 2. (918 aa) |
| | ENSPMGP00000002437 | Uncharacterized protein. (283 aa) |
| | ENSPMGP00000002742 | RING-type domain-containing protein. (121 aa) |
| | ENSPMGP00000003482 | Abraxas 1, BRCA1 A complex subunit. (335 aa) |
| | ENSPMGP00000003939 | Uncharacterized protein; Belongs to the histone H2B family. (103 aa) |
| | ENSPMGP00000003957 | Replication factor C (activator 1) 2. (342 aa) |
| | ENSPMGP00000004508 | RAD9 checkpoint clamp component B. (183 aa) |
| | SFN | Stratifin; Belongs to the 14-3-3 family. (148 aa) |
| | ENSPMGP00000005322 | Uncharacterized protein. (141 aa) |
| | ENSPMGP00000005337 | Replication protein A2. (280 aa) |
| | ENSPMGP00000005554 | RecQ mediated genome instability 2. (149 aa) |
| | ENSPMGP00000005957 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (412 aa) |
| | ENSPMGP00000005992 | BRCA1/BRCA2-containing complex, subunit 3. (272 aa) |
| | ENSPMGP00000006737 | RAD17 checkpoint clamp loader component. (472 aa) |
| | ENSPMGP00000007021 | BRISC and BRCA1 A complex member 2. (326 aa) |
| | ENSPMGP00000008014 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (896 aa) |
| | ENSPMGP00000008434 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (99 aa) |
| | ENSPMGP00000008638 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa) |
| | ENSPMGP00000008667 | Histone H2B; Belongs to the histone H2B family. (110 aa) |
| | ENSPMGP00000008747 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa) |
| | ENSPMGP00000010052 | annotation not available (124 aa) |
| | ENSPMGP00000010071 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (454 aa) |
| | ENSPMGP00000010440 | Cell cycle checkpoint control protein; Belongs to the rad9 family. (385 aa) |
| | ENSPMGP00000010557 | Methionine sulfoxide reductase B1b. (383 aa) |
| | ENSPMGP00000010951 | Wee1-like protein kinase. (636 aa) |
| | ENSPMGP00000011190 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (241 aa) |
| | ENSPMGP00000011645 | MRE11 homolog A, double strand break repair nuclease. (451 aa) |
| | ENSPMGP00000011646 | Metallophos domain-containing protein. (104 aa) |
| | ENSPMGP00000011905 | RING-type domain-containing protein. (103 aa) |
| | ENSPMGP00000012369 | Histone H2B; Belongs to the histone H2B family. (111 aa) |
| | ENSPMGP00000013512 | DNA topoisomerase II binding protein 1. (1436 aa) |
| | ENSPMGP00000013690 | BRCT domain-containing protein. (564 aa) |
| | ENSPMGP00000013868 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa) |
| | ENSPMGP00000013995 | Histone H2B; Belongs to the histone H2B family. (113 aa) |
| | ENSPMGP00000014113 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (568 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (275 aa) |
| | ENSPMGP00000014769 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (244 aa) |
| | ENSPMGP00000015624 | Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (307 aa) |
| | ENSPMGP00000015634 | Uncharacterized protein. (67 aa) |
| | ENSPMGP00000015665 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | ENSPMGP00000016014 | Histone H2B; Belongs to the histone H2B family. (118 aa) |
| | ENSPMGP00000016157 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (165 aa) |
| | ENSPMGP00000016158 | Histone H2B; Belongs to the histone H2B family. (156 aa) |
| | ENSPMGP00000016554 | 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1; Belongs to the 14-3-3 family. (275 aa) |
| | ENSPMGP00000016599 | BRCT domain-containing protein. (176 aa) |
| | ENSPMGP00000016603 | ANK_REP_REGION domain-containing protein. (261 aa) |
| | ENSPMGP00000016967 | Ankyrin repeat domain 11. (2717 aa) |
| | ENSPMGP00000018039 | BRISC and BRCA1 A complex member 1. (380 aa) |
| | ENSPMGP00000018043 | Protein inhibitor of activated STAT, 4a. (503 aa) |
| | ENSPMGP00000018443 | Histone H2B; Belongs to the histone H2B family. (108 aa) |
| | ENSPMGP00000018529 | Replication factor C (activator 1) 5. (336 aa) |
| | ENSPMGP00000018715 | Checkpoint kinase 2. (476 aa) |
| | ENSPMGP00000018716 | Tudor domain containing 3. (757 aa) |
| | ENSPMGP00000018756 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (251 aa) |
| | ENSPMGP00000019260 | annotation not available (245 aa) |
| | ENSPMGP00000019300 | Uncharacterized protein; Belongs to the histone H2B family. (115 aa) |
| | ENSPMGP00000019369 | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2737 aa) |
| | ENSPMGP00000019587 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2554 aa) |
| | ENSPMGP00000019885 | Uncharacterized protein. (161 aa) |
| | ENSPMGP00000020400 | Replication factor C (activator 1) 4. (358 aa) |
| | H4C2 | H4 clustered histone 2. (103 aa) |
| | ENSPMGP00000021764 | Histone H2B; Belongs to the histone H2B family. (128 aa) |
| | ENSPMGP00000021944 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (929 aa) |
| | ENSPMGP00000022998 | Histone H2A; Belongs to the histone H2A family. (137 aa) |
| | ENSPMGP00000023519 | Uncharacterized protein. (465 aa) |
| | ENSPMGP00000023998 | annotation not available (124 aa) |
| | ENSPMGP00000024084 | Exonuclease 1. (559 aa) |
| | ENSPMGP00000024148 | RAD50 homolog, double strand break repair protein. (1270 aa) |
| | UBE2N | Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) |
| | ENSPMGP00000024731 | Nuclear receptor binding SET domain protein 2. (1123 aa) |
| | ENSPMGP00000024916 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (548 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (465 aa) |
| | ENSPMGP00000026072 | Exonuclease 3'-5' domain containing 2. (626 aa) |
| | ENSPMGP00000026090 | Cell division cycle 25B. (454 aa) |
| | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (252 aa) |
| | ENSPMGP00000026408 | Replication protein A3. (122 aa) |
| | ENSPMGP00000026544 | RecQ helicase-like 4. (1317 aa) |
| | ENSPMGP00000026851 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (100 aa) |
| | ENSPMGP00000027900 | annotation not available (92 aa) |
| | ENSPMGP00000028252 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (243 aa) |
| | ENSPMGP00000028441 | Cyclin B1; Belongs to the cyclin family. (401 aa) |
| | ENSPMGP00000028552 | RAD1 homolog (S. pombe). (281 aa) |
| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b; Belongs to the 14-3-3 family. (235 aa) |
| | ENSPMGP00000028736 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (251 aa) |
| | ENSPMGP00000029368 | Replication factor C (activator 1) 3. (270 aa) |
| | ENSPMGP00000029700 | Uncharacterized protein. (1612 aa) |
