STRINGSTRING
ENSPMGP00000023271 ENSPMGP00000023271 ENSPMGP00000002787 ENSPMGP00000002787 ENSPMGP00000002793 ENSPMGP00000002793 ENSPMGP00000002858 ENSPMGP00000002858 ENSPMGP00000003741 ENSPMGP00000003741 ENSPMGP00000003939 ENSPMGP00000003939 ENSPMGP00000003957 ENSPMGP00000003957 ENSPMGP00000003968 ENSPMGP00000003968 ENSPMGP00000004107 ENSPMGP00000004107 ENSPMGP00000004122 ENSPMGP00000004122 ENSPMGP00000004216 ENSPMGP00000004216 ENSPMGP00000004772 ENSPMGP00000004772 ENSPMGP00000004977 ENSPMGP00000004977 ENSPMGP00000005307 ENSPMGP00000005307 ENSPMGP00000005337 ENSPMGP00000005337 ENSPMGP00000006344 ENSPMGP00000006344 ENSPMGP00000007496 ENSPMGP00000007496 ENSPMGP00000008434 ENSPMGP00000008434 ENSPMGP00000008510 ENSPMGP00000008510 ENSPMGP00000008537 ENSPMGP00000008537 ENSPMGP00000008638 ENSPMGP00000008638 ENSPMGP00000008667 ENSPMGP00000008667 ENSPMGP00000008747 ENSPMGP00000008747 ENSPMGP00000009018 ENSPMGP00000009018 ENSPMGP00000010052 ENSPMGP00000010052 ENSPMGP00000010557 ENSPMGP00000010557 ENSPMGP00000010788 ENSPMGP00000010788 ENSPMGP00000011036 ENSPMGP00000011036 ENSPMGP00000011542 ENSPMGP00000011542 ENSPMGP00000012369 ENSPMGP00000012369 RCBTB1 RCBTB1 ENSPMGP00000013868 ENSPMGP00000013868 ENSPMGP00000013995 ENSPMGP00000013995 ENSPMGP00000014113 ENSPMGP00000014113 ENSPMGP00000014257 ENSPMGP00000014257 ENSPMGP00000015622 ENSPMGP00000015622 ENSPMGP00000015665 ENSPMGP00000015665 ENSPMGP00000015873 ENSPMGP00000015873 ENSPMGP00000016014 ENSPMGP00000016014 ENSPMGP00000016157 ENSPMGP00000016157 ENSPMGP00000016158 ENSPMGP00000016158 ENSPMGP00000016642 ENSPMGP00000016642 ENSPMGP00000016861 ENSPMGP00000016861 ENSPMGP00000018021 ENSPMGP00000018021 ENSPMGP00000018175 ENSPMGP00000018175 ENSPMGP00000018443 ENSPMGP00000018443 ENSPMGP00000018529 ENSPMGP00000018529 ENSPMGP00000019186 ENSPMGP00000019186 ENSPMGP00000019260 ENSPMGP00000019260 ENSPMGP00000019300 ENSPMGP00000019300 ENSPMGP00000019478 ENSPMGP00000019478 NTHL1 NTHL1 ENSPMGP00000020400 ENSPMGP00000020400 ENSPMGP00000020518 ENSPMGP00000020518 H4C2 H4C2 ENSPMGP00000021762 ENSPMGP00000021762 ENSPMGP00000021764 ENSPMGP00000021764 ENSPMGP00000022767 ENSPMGP00000022767 ENSPMGP00000022771 ENSPMGP00000022771 ENSPMGP00000022931 ENSPMGP00000022931 ENSPMGP00000022998 ENSPMGP00000022998 UNG UNG ENSPMGP00000002767 ENSPMGP00000002767 ENSPMGP00000023441 ENSPMGP00000023441 ENSPMGP00000023442 ENSPMGP00000023442 ENSPMGP00000023998 ENSPMGP00000023998 FEN1 FEN1 ENSPMGP00000026065 ENSPMGP00000026065 ENSPMGP00000026408 ENSPMGP00000026408 ENSPMGP00000026851 ENSPMGP00000026851 ENSPMGP00000027525 ENSPMGP00000027525 ENSPMGP00000027653 ENSPMGP00000027653 ENSPMGP00000027896 ENSPMGP00000027896 ENSPMGP00000027900 ENSPMGP00000027900 ENSPMGP00000028425 ENSPMGP00000028425 ENSPMGP00000028598 ENSPMGP00000028598 ENSPMGP00000029368 ENSPMGP00000029368 ENSPMGP00000029939 ENSPMGP00000029939 ENSPMGP00000030014 ENSPMGP00000030014 ENSPMGP00000030015 ENSPMGP00000030015 ENSPMGP00000002223 ENSPMGP00000002223 ENSPMGP00000001872 ENSPMGP00000001872 ENSPMGP00000001504 ENSPMGP00000001504 ENSPMGP00000001334 ENSPMGP00000001334 RPA1 RPA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPMGP00000023271TINF2_N domain-containing protein. (445 aa)
ENSPMGP00000002787Polymerase (DNA directed), epsilon 2. (325 aa)
ENSPMGP00000002793Poly [ADP-ribose] polymerase. (624 aa)
ENSPMGP00000002858Uncharacterized protein. (158 aa)
ENSPMGP00000003741Histone H2A; Belongs to the histone H2A family. (135 aa)
ENSPMGP00000003939Uncharacterized protein; Belongs to the histone H2B family. (103 aa)
ENSPMGP00000003957Replication factor C (activator 1) 2. (342 aa)
ENSPMGP00000003968Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (248 aa)
ENSPMGP00000004107Thymine DNA glycosylase, tandem duplicate 1. (379 aa)
ENSPMGP00000004122Histone H2A; Belongs to the histone H2A family. (136 aa)
ENSPMGP00000004216Thymine DNA glycosylase, tandem duplicate 1. (356 aa)
ENSPMGP00000004772Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (571 aa)
ENSPMGP00000004977N-methylpurine DNA glycosylase. (283 aa)
ENSPMGP00000005307Polymerase (DNA directed), epsilon 3 (p17 subunit). (146 aa)
ENSPMGP00000005337Replication protein A2. (280 aa)
ENSPMGP00000006344Poly [ADP-ribose] polymerase. (532 aa)
ENSPMGP00000007496Uncharacterized protein. (131 aa)
ENSPMGP00000008434Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (99 aa)
ENSPMGP00000008510Nei-like DNA glycosylase 3. (533 aa)
ENSPMGP00000008537Polynucleotide kinase 3'-phosphatase. (590 aa)
ENSPMGP00000008638Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
ENSPMGP00000008667Histone H2B; Belongs to the histone H2B family. (110 aa)
ENSPMGP00000008747Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa)
ENSPMGP00000009018Nei-like DNA glycosylase 1. (397 aa)
ENSPMGP00000010052annotation not available (124 aa)
ENSPMGP00000010557Methionine sulfoxide reductase B1b. (383 aa)
ENSPMGP00000010788Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (975 aa)
ENSPMGP00000011036DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (549 aa)
ENSPMGP00000011542ATPase_AAA_core domain-containing protein. (799 aa)
ENSPMGP00000012369Histone H2B; Belongs to the histone H2B family. (111 aa)
RCBTB1Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (350 aa)
ENSPMGP00000013868Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa)
ENSPMGP00000013995Histone H2B; Belongs to the histone H2B family. (113 aa)
ENSPMGP00000014113Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (568 aa)
ENSPMGP00000014257Telo_bind domain-containing protein. (352 aa)
ENSPMGP000000156228-oxoguanine DNA glycosylase. (383 aa)
ENSPMGP00000015665Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ENSPMGP00000015873Histone_H2A_C domain-containing protein; Belongs to the histone H2A family. (116 aa)
ENSPMGP00000016014Histone H2B; Belongs to the histone H2B family. (118 aa)
ENSPMGP00000016157Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (165 aa)
ENSPMGP00000016158Histone H2B; Belongs to the histone H2B family. (156 aa)
ENSPMGP00000016642Zgc:110269. (304 aa)
ENSPMGP00000016861Methyl-CpG binding domain protein 4. (192 aa)
ENSPMGP00000018021Von Willebrand factor A domain containing 5B2. (976 aa)
ENSPMGP00000018175Uncharacterized protein. (405 aa)
ENSPMGP00000018443Histone H2B; Belongs to the histone H2B family. (108 aa)
ENSPMGP00000018529Replication factor C (activator 1) 5. (336 aa)
ENSPMGP00000019186DNA polymerase. (1034 aa)
ENSPMGP00000019260annotation not available (245 aa)
ENSPMGP00000019300Uncharacterized protein; Belongs to the histone H2B family. (115 aa)
ENSPMGP00000019478Histone H2A; Belongs to the histone H2A family. (97 aa)
NTHL1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (336 aa)
ENSPMGP00000020400Replication factor C (activator 1) 4. (358 aa)
ENSPMGP00000020518DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (333 aa)
H4C2H4 clustered histone 2. (103 aa)
ENSPMGP00000021762Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSPMGP00000021764Histone H2B; Belongs to the histone H2B family. (128 aa)
ENSPMGP00000022767DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (202 aa)
ENSPMGP00000022771DNA_pol_B_thumb domain-containing protein. (54 aa)
ENSPMGP00000022931DNA ligase. (895 aa)
ENSPMGP00000022998Histone H2A; Belongs to the histone H2A family. (137 aa)
UNGUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (303 aa)
ENSPMGP00000002767Dpoe2NT domain-containing protein. (92 aa)
ENSPMGP00000023441DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (310 aa)
ENSPMGP00000023442DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (328 aa)
ENSPMGP00000023998annotation not available (124 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (381 aa)
ENSPMGP00000026065X-ray repair complementing defective repair in Chinese hamster cells 1. (567 aa)
ENSPMGP00000026408Replication protein A3. (122 aa)
ENSPMGP00000026851Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (100 aa)
ENSPMGP00000027525Polymerase (DNA-directed), epsilon 4, accessory subunit. (131 aa)
ENSPMGP00000027653Single-strand-selective monofunctional uracil-DNA glycosylase 1. (288 aa)
ENSPMGP00000027896Si:dkey-28b4.7. (119 aa)
ENSPMGP00000027900annotation not available (92 aa)
ENSPMGP00000028425Uncharacterized protein. (725 aa)
ENSPMGP00000028598Polymerase (DNA directed), delta 2, regulatory subunit. (446 aa)
ENSPMGP00000029368Replication factor C (activator 1) 3. (270 aa)
ENSPMGP00000029939ADP-ribosylhydrolase like 2. (385 aa)
ENSPMGP00000030014BRCT domain-containing protein. (398 aa)
ENSPMGP00000030015RFC1 domain-containing protein. (135 aa)
ENSPMGP00000002223Uncharacterized protein. (458 aa)
ENSPMGP00000001872Poly (ADP-ribose) glycohydrolase a. (626 aa)
ENSPMGP00000001504Uncharacterized protein; Belongs to the histone H2A family. (245 aa)
ENSPMGP00000001334Histone H2A; Belongs to the histone H2A family. (134 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (587 aa)
Your Current Organism:
Periophthalmus magnuspinnatus
NCBI taxonomy Id: 409849
Other names: P. magnuspinnatus
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