(17 nodes) Breast cancer carboxy-terminal domain network (Periophthalmus magnuspinnatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPMGP00000016417	DNA ligase. (913 aa)
	ENSPMGP00000016599	BRCT domain-containing protein. (176 aa)
	PES1	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (551 aa)
	ENSPMGP00000026065	X-ray repair complementing defective repair in Chinese hamster cells 1. (567 aa)
	ENSPMGP00000013512	DNA topoisomerase II binding protein 1. (1436 aa)
	ENSPMGP00000012544	BRCT domain-containing protein. (357 aa)
	ENSPMGP00000010788	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (975 aa)
	ENSPMGP00000029700	Uncharacterized protein. (1612 aa)
	ENSPMGP00000030014	BRCT domain-containing protein. (398 aa)
	ENSPMGP00000026605	DBF4 zinc finger. (529 aa)
	ENSPMGP00000026644	Nibrin. (675 aa)
	ENSPMGP00000027667	Epithelial cell transforming 2. (867 aa)
	ENSPMGP00000028030	BRCT domain-containing protein. (221 aa)
	ENSPMGP00000028311	Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (528 aa)
	ENSPMGP00000013670	DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (497 aa)
	ENSPMGP00000028678	BRCT domain-containing protein. (508 aa)
	ENSPMGP00000015520	BRCT domain-containing protein. (144 aa)

Your Current Organism:

Periophthalmus magnuspinnatus

NCBI taxonomy Id: 409849
Other names: P. magnuspinnatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPMGP00000010788	ENSPMGP00000013670	ENSPMGP00000010788	ENSPMGP00000013670	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family.	0.615
ENSPMGP00000010788	ENSPMGP00000016417	ENSPMGP00000010788	ENSPMGP00000016417	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	DNA ligase.	0.618
ENSPMGP00000010788	ENSPMGP00000026065	ENSPMGP00000010788	ENSPMGP00000026065	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.933
ENSPMGP00000010788	ENSPMGP00000028030	ENSPMGP00000010788	ENSPMGP00000028030	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	BRCT domain-containing protein.	0.574
ENSPMGP00000010788	ENSPMGP00000028311	ENSPMGP00000010788	ENSPMGP00000028311	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family.	0.728
ENSPMGP00000010788	ENSPMGP00000030014	ENSPMGP00000010788	ENSPMGP00000030014	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	BRCT domain-containing protein.	0.583
ENSPMGP00000012544	ENSPMGP00000016417	ENSPMGP00000012544	ENSPMGP00000016417	BRCT domain-containing protein.	DNA ligase.	0.734
ENSPMGP00000012544	ENSPMGP00000026065	ENSPMGP00000012544	ENSPMGP00000026065	BRCT domain-containing protein.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.704
ENSPMGP00000012544	ENSPMGP00000026605	ENSPMGP00000012544	ENSPMGP00000026605	BRCT domain-containing protein.	DBF4 zinc finger.	0.422
ENSPMGP00000012544	ENSPMGP00000028030	ENSPMGP00000012544	ENSPMGP00000028030	BRCT domain-containing protein.	BRCT domain-containing protein.	0.588
ENSPMGP00000012544	ENSPMGP00000028311	ENSPMGP00000012544	ENSPMGP00000028311	BRCT domain-containing protein.	Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family.	0.551
ENSPMGP00000012544	ENSPMGP00000028678	ENSPMGP00000012544	ENSPMGP00000028678	BRCT domain-containing protein.	BRCT domain-containing protein.	0.464
ENSPMGP00000012544	ENSPMGP00000030014	ENSPMGP00000012544	ENSPMGP00000030014	BRCT domain-containing protein.	BRCT domain-containing protein.	0.730
ENSPMGP00000013512	ENSPMGP00000015520	ENSPMGP00000013512	ENSPMGP00000015520	DNA topoisomerase II binding protein 1.	BRCT domain-containing protein.	0.842
ENSPMGP00000013512	ENSPMGP00000016599	ENSPMGP00000013512	ENSPMGP00000016599	DNA topoisomerase II binding protein 1.	BRCT domain-containing protein.	0.420
ENSPMGP00000013512	ENSPMGP00000026065	ENSPMGP00000013512	ENSPMGP00000026065	DNA topoisomerase II binding protein 1.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.433
ENSPMGP00000013512	ENSPMGP00000026605	ENSPMGP00000013512	ENSPMGP00000026605	DNA topoisomerase II binding protein 1.	DBF4 zinc finger.	0.691
ENSPMGP00000013512	ENSPMGP00000028030	ENSPMGP00000013512	ENSPMGP00000028030	DNA topoisomerase II binding protein 1.	BRCT domain-containing protein.	0.988
ENSPMGP00000013512	ENSPMGP00000028678	ENSPMGP00000013512	ENSPMGP00000028678	DNA topoisomerase II binding protein 1.	BRCT domain-containing protein.	0.864
ENSPMGP00000013512	ENSPMGP00000029700	ENSPMGP00000013512	ENSPMGP00000029700	DNA topoisomerase II binding protein 1.	Uncharacterized protein.	0.935