STRINGSTRING
CDV56_104576 CDV56_104576 CDV56_108480 CDV56_108480 POB3 POB3 CDV56_102259 CDV56_102259 CDV56_105944 CDV56_105944 CDV56_104127 CDV56_104127 LET1 LET1 CDV56_102527 CDV56_102527 HTB1 HTB1 CDV56_106589 CDV56_106589 SPT6 SPT6 CDV56_104973 CDV56_104973 CDV56_106555 CDV56_106555 RAD5 RAD5 CDV56_106077 CDV56_106077 INO80 INO80 CDV56_107162 CDV56_107162 TEL1 TEL1 CDV56_104184 CDV56_104184 CDV56_104941 CDV56_104941 CDV56_107774 CDV56_107774 CDV56_107158 CDV56_107158 CDV56_106843 CDV56_106843 CDV56_103679 CDV56_103679 CDV56_100575 CDV56_100575 CDV56_107379 CDV56_107379 CDV56_102236 CDV56_102236 CDV56_104899 CDV56_104899 CDV56_104888 CDV56_104888 NCB2 NCB2 CHZ1 CHZ1 CDV56_107238 CDV56_107238 HTZ1 HTZ1 HTA1 HTA1 CDV56_106316 CDV56_106316 HAT2 HAT2 CDV56_105359 CDV56_105359 CDV56_107582 CDV56_107582 CDV56_107053 CDV56_107053 CDV56_107214 CDV56_107214 CDV56_104759 CDV56_104759 CDV56_102120 CDV56_102120 CDV56_108362 CDV56_108362 CDV56_104102 CDV56_104102 MCM5 MCM5 CDV56_101797 CDV56_101797 ESA1 ESA1 CDV56_102755 CDV56_102755 CDV56_107967 CDV56_107967 CDV56_108212 CDV56_108212 CDV56_107432 CDV56_107432 CDV56_107349 CDV56_107349 CDV56_100271 CDV56_100271 CDV56_100343 CDV56_100343 CDV56_104317 CDV56_104317 CDV56_107122 CDV56_107122 CDV56_108606 CDV56_108606 CDV56_106953 CDV56_106953 GCN5 GCN5 CDV56_109612 CDV56_109612 SET9 SET9 CDV56_109270 CDV56_109270 CDV56_108209 CDV56_108209 CDV56_109541 CDV56_109541 CDV56_109693 CDV56_109693 CDV56_109376 CDV56_109376 SWC4 SWC4 CDV56_107742 CDV56_107742 CDV56_104210 CDV56_104210 FPR4 FPR4 CDV56_107574 CDV56_107574 SWR1 SWR1 CDV56_108043 CDV56_108043 CDV56_106868 CDV56_106868 CDV56_106786 CDV56_106786 CDV56_107040 CDV56_107040 CDV56_102938 CDV56_102938 CDV56_105859 CDV56_105859 CDV56_108614 CDV56_108614 CDV56_105651 CDV56_105651 JHD1 JHD1 CDV56_107925 CDV56_107925 CDV56_108203 CDV56_108203 CDV56_103358 CDV56_103358 ARP6 ARP6 CDV56_105623 CDV56_105623 UBC2 UBC2 SET1 SET1 CDV56_106844 CDV56_106844 HIR3 HIR3 CDV56_108617 CDV56_108617 CDV56_108888 CDV56_108888 CDV56_108481 CDV56_108481 CDV56_108222 CDV56_108222 RBX1 RBX1 CDV56_107169 CDV56_107169 CDV56_108713 CDV56_108713 CDV56_104990 CDV56_104990 CDV56_107285 CDV56_107285 CDV56_103545 CDV56_103545 DOT1 DOT1 CDV56_107906 CDV56_107906 YAF9 YAF9 CDV56_105500 CDV56_105500 CDV56_108545 CDV56_108545 CDV56_107497 CDV56_107497 CDV56_103270 CDV56_103270 SWC5 SWC5 CDV56_105021 CDV56_105021 CDV56_101628 CDV56_101628 SPT4 SPT4 CDV56_102788 CDV56_102788 CDV56_104572 CDV56_104572 HAT1 HAT1 CDV56_104388 CDV56_104388 HSP90 HSP90 CDV56_104513 CDV56_104513 CDV56_102103 CDV56_102103 CDV56_105366 CDV56_105366 ARP4 ARP4 CDV56_100211 CDV56_100211 EAF3 EAF3 CDV56_102502 CDV56_102502 CDV56_101499 CDV56_101499 HIR1 HIR1 CDV56_104634 CDV56_104634 CDV56_102225 CDV56_102225 RVB1 RVB1 CDV56_103527 CDV56_103527 CDV56_104494 CDV56_104494 CDV56_100659 CDV56_100659 CDV56_106136 CDV56_106136 CDV56_103473 CDV56_103473 CDV56_103132 CDV56_103132 CDV56_102258 CDV56_102258 ASA1 ASA1 CDV56_101472 CDV56_101472 CDV56_102961 CDV56_102961 CDV56_103182 CDV56_103182 CDV56_100378 CDV56_100378 CDV56_103734 CDV56_103734 CDV56_103978 CDV56_103978 CDV56_103767 CDV56_103767 CDV56_102089 CDV56_102089 CDV56_102128 CDV56_102128 CDV56_100669 CDV56_100669 CDV56_103757 CDV56_103757 CDV56_103174 CDV56_103174 CDV56_101979 CDV56_101979 CDV56_104095 CDV56_104095 CDV56_104097 CDV56_104097 CDV56_101602 CDV56_101602 CDV56_101924 CDV56_101924 CDV56_101409 CDV56_101409 CDV56_101921 CDV56_101921 CDV56_104078 CDV56_104078 CDV56_103583 CDV56_103583 CDV56_103598 CDV56_103598 ASF1 ASF1 CDV56_102245 CDV56_102245 CDV56_100738 CDV56_100738 CDV56_100979 CDV56_100979 CDV56_102989 CDV56_102989 CDV56_102030 CDV56_102030 RCO1 RCO1 CDV56_101523 CDV56_101523 CDV56_100864 CDV56_100864 BRE1 BRE1 CDV56_102844 CDV56_102844 EAF1 EAF1 CDV56_104695 CDV56_104695 RVB2 RVB2 CDV56_109153 CDV56_109153 CDV56_107321 CDV56_107321 CDV56_104674 CDV56_104674 CDV56_106254 CDV56_106254 CDV56_109323 CDV56_109323 CDV56_108963 CDV56_108963 CDV56_107524 CDV56_107524 CDV56_104804 CDV56_104804 MCM7 MCM7 CDV56_109523 CDV56_109523 CDV56_108616 CDV56_108616
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDV56_104576Uncharacterized protein. (373 aa)
CDV56_108480Uncharacterized protein. (402 aa)
POB3FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (598 aa)
CDV56_102259Uncharacterized protein. (716 aa)
CDV56_105944Beta-lactamase domain-containing protein. (430 aa)
CDV56_104127Uncharacterized protein. (248 aa)
LET126S protease regulatory subunit 8; Belongs to the AAA ATPase family. (389 aa)
CDV56_102527Uncharacterized protein. (890 aa)
HTB1Histone H2B; Belongs to the histone H2B family. (140 aa)
CDV56_106589Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2061 aa)
SPT6Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1421 aa)
CDV56_104973Uncharacterized protein. (708 aa)
CDV56_106555Uncharacterized protein. (262 aa)
RAD5DNA helicase rad5. (1248 aa)
CDV56_106077Zn(2)-C6 fungal-type domain-containing protein. (891 aa)
INO80Putative DNA helicase ino80. (1707 aa)
CDV56_107162SNF2_N domain-containing protein. (252 aa)
TEL1Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2904 aa)
CDV56_104184UCH_1 domain-containing protein. (415 aa)
CDV56_104941Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (357 aa)
CDV56_107774Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
CDV56_107158Uncharacterized protein. (1202 aa)
CDV56_106843HMG box domain-containing protein. (373 aa)
CDV56_103679CULLIN_2 domain-containing protein; Belongs to the cullin family. (2550 aa)
CDV56_100575Uncharacterized protein. (967 aa)
CDV56_107379NET domain-containing protein. (232 aa)
CDV56_102236Rtt106 domain-containing protein. (459 aa)
CDV56_104899N-acetyltransferase domain-containing protein. (280 aa)
CDV56_104888Uncharacterized protein. (1409 aa)
NCB2Negative cofactor 2 transcription regulator complex subunit ncb2. (142 aa)
CHZ1Histone H2A.Z-specific chaperone. (121 aa)
CDV56_107238Uncharacterized protein. (411 aa)
HTZ1Histone H2A; Belongs to the histone H2A family. (138 aa)
HTA1Histone H2A; Belongs to the histone H2A family. (133 aa)
CDV56_106316Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (801 aa)
HAT2Histone acetyltransferase type B subunit 2. (436 aa)
CDV56_105359Uncharacterized protein. (372 aa)
CDV56_107582Uncharacterized protein. (1515 aa)
CDV56_107053RNA-dependent RNA polymerase. (1433 aa)
CDV56_107214YL1_C domain-containing protein. (747 aa)
CDV56_104759Sister chromatid cohesion protein. (1771 aa)
CDV56_102120Hist_deacetyl domain-containing protein. (696 aa)
CDV56_108362Uncharacterized protein. (277 aa)
CDV56_104102Stc1 domain-containing protein. (265 aa)
MCM5DNA helicase; Belongs to the MCM family. (719 aa)
CDV56_101797Uncharacterized protein. (372 aa)
ESA1Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (510 aa)
CDV56_102755Uncharacterized protein. (528 aa)
CDV56_107967Uncharacterized protein. (673 aa)
CDV56_108212Uncharacterized protein. (340 aa)
CDV56_107432Uncharacterized protein; Belongs to the actin family. (755 aa)
CDV56_107349YL1_C domain-containing protein. (185 aa)
CDV56_100271Uncharacterized protein. (86 aa)
CDV56_100343SAGA-associated factor 11; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA [...] (348 aa)
CDV56_104317Uncharacterized protein. (700 aa)
CDV56_107122Uncharacterized protein; Belongs to the actin family. (688 aa)
CDV56_108606Flavin_Reduct domain-containing protein. (315 aa)
CDV56_106953SWIRM domain-containing protein. (379 aa)
GCN5Histone acetyltransferase. (408 aa)
CDV56_109612HRDC domain-containing protein. (769 aa)
SET9Histone-lysine N-methyltransferase set9. (626 aa)
CDV56_109270ARID domain-containing protein. (983 aa)
CDV56_108209RXT2_N domain-containing protein. (511 aa)
CDV56_109541Uncharacterized protein. (1193 aa)
CDV56_109693Uncharacterized protein. (346 aa)
CDV56_109376Uncharacterized protein. (794 aa)
SWC4Swr complex subunit. (596 aa)
CDV56_107742DNA helicase; Belongs to the MCM family. (889 aa)
CDV56_104210Uncharacterized protein. (1897 aa)
FPR4FK506-binding protein. (482 aa)
CDV56_107574WD_REPEATS_REGION domain-containing protein. (551 aa)
SWR1Swr1 complex component. (1694 aa)
CDV56_108043Uncharacterized protein. (170 aa)
CDV56_106868Uncharacterized protein. (1479 aa)
CDV56_106786Uncharacterized protein. (635 aa)
CDV56_107040WD_REPEATS_REGION domain-containing protein. (635 aa)
CDV56_102938Uncharacterized protein. (1184 aa)
CDV56_105859Uncharacterized protein. (2166 aa)
CDV56_108614C2H2-type domain-containing protein. (920 aa)
CDV56_105651Uncharacterized protein. (348 aa)
JHD1JmjC domain-containing histone demethylation protein 1. (1424 aa)
CDV56_107925PHD-type domain-containing protein. (475 aa)
CDV56_108203SWIB domain-containing protein. (508 aa)
CDV56_103358Uncharacterized protein. (1163 aa)
ARP6Actin-protein 6; Belongs to the actin family. (468 aa)
CDV56_105623Uncharacterized protein. (675 aa)
UBC2Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
SET1Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1242 aa)
CDV56_106844NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily. (422 aa)
HIR3Histone transcription regulator 3. (2020 aa)
CDV56_108617Uncharacterized protein. (810 aa)
CDV56_108888Uncharacterized protein. (570 aa)
CDV56_108481Uncharacterized protein. (313 aa)
CDV56_108222RFX-type winged-helix domain-containing protein. (685 aa)
RBX1RING-box protein 1. (100 aa)
CDV56_107169Uncharacterized protein. (1887 aa)
CDV56_108713zf-C3H1 domain-containing protein. (1305 aa)
CDV56_104990B30.2/SPRY domain-containing protein. (617 aa)
CDV56_107285Uncharacterized protein. (259 aa)
CDV56_103545Chromo domain-containing protein. (210 aa)
DOT1Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (503 aa)
CDV56_107906Beta-lactamase domain-containing protein. (391 aa)
YAF9NuA4 histone H4 acetyltransferase complex and the SWR1 complex subunit. (252 aa)
CDV56_105500Uncharacterized protein. (250 aa)
CDV56_108545Chromo domain-containing protein. (1221 aa)
CDV56_107497HUN domain-containing protein. (376 aa)
CDV56_103270Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa)
SWC5Swr complex subunit. (359 aa)
CDV56_105021Uncharacterized protein. (1490 aa)
CDV56_101628Uncharacterized protein. (1735 aa)
SPT4Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (122 aa)
CDV56_102788Uncharacterized protein. (833 aa)
CDV56_104572Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (487 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (509 aa)
CDV56_104388SHNi-TPR domain-containing protein. (463 aa)
HSP90Heat shock protein 90. (704 aa)
CDV56_104513Uncharacterized protein. (1121 aa)
CDV56_102103Uncharacterized protein. (846 aa)
CDV56_105366Uncharacterized protein. (1012 aa)
ARP4NuA4 histone acetyltransferase subunit; Belongs to the actin family. (472 aa)
CDV56_100211Uncharacterized protein. (1090 aa)
EAF3Esa1p-associated factor. (330 aa)
CDV56_102502Uncharacterized protein. (715 aa)
CDV56_101499Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (99 aa)
HIR1Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1063 aa)
CDV56_104634tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. (488 aa)
CDV56_102225WD_REPEATS_REGION domain-containing protein. (1065 aa)
RVB1RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (458 aa)
CDV56_103527ANK_REP_REGION domain-containing protein. (605 aa)
CDV56_104494Uncharacterized protein. (174 aa)
CDV56_100659Uncharacterized protein. (640 aa)
CDV56_106136APH domain-containing protein. (292 aa)
CDV56_103473Deacetylase sirtuin-type domain-containing protein. (612 aa)
CDV56_103132MFS domain-containing protein. (1670 aa)
CDV56_102258AAA domain-containing protein. (706 aa)
ASA1ASTRA complex subunit. (447 aa)
CDV56_101472Uncharacterized protein. (1132 aa)
CDV56_102961Uncharacterized protein. (287 aa)
CDV56_103182PAPA-1 domain-containing protein. (322 aa)
CDV56_100378Uncharacterized protein. (1660 aa)
CDV56_103734Uncharacterized protein. (303 aa)
CDV56_103978Uncharacterized protein. (1214 aa)
CDV56_103767Structural maintenance of chromosomes protein. (1179 aa)
CDV56_102089Uncharacterized protein. (964 aa)
CDV56_102128Uncharacterized protein. (528 aa)
CDV56_100669WD_REPEATS_REGION domain-containing protein. (479 aa)
CDV56_103757Helicase ATP-binding domain-containing protein. (1141 aa)
CDV56_103174C3H1-type domain-containing protein. (1246 aa)
CDV56_101979Bromo domain-containing protein. (1182 aa)
CDV56_104095Helicase C-terminal domain-containing protein. (328 aa)
CDV56_104097Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (1242 aa)
CDV56_101602Uncharacterized protein. (1830 aa)
CDV56_101924Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1058 aa)
CDV56_101409Uncharacterized protein. (665 aa)
CDV56_101921Uncharacterized protein. (310 aa)
CDV56_104078CBFD_NFYB_HMF domain-containing protein. (216 aa)
CDV56_103583Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (373 aa)
CDV56_103598Uncharacterized protein. (93 aa)
ASF1Histone chaperone asf1. (152 aa)
CDV56_102245Uncharacterized protein. (731 aa)
CDV56_100738Uncharacterized protein. (777 aa)
CDV56_100979JmjC domain-containing protein. (576 aa)
CDV56_102989Uncharacterized protein. (111 aa)
CDV56_102030PHD-type domain-containing protein. (861 aa)
RCO1Transcriptional regulatory protein rco1. (588 aa)
CDV56_101523Uncharacterized protein. (203 aa)
CDV56_100864Uncharacterized protein. (542 aa)
BRE1E3 ubiquitin protein ligase. (725 aa)
CDV56_102844Uncharacterized protein. (797 aa)
EAF1Chromatin modification-protein VID21. (1467 aa)
CDV56_104695Uncharacterized protein. (219 aa)
RVB2RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (469 aa)
CDV56_109153Uncharacterized protein. (589 aa)
CDV56_107321Uncharacterized protein. (1425 aa)
CDV56_104674Uncharacterized protein. (730 aa)
CDV56_106254Uncharacterized protein. (697 aa)
CDV56_109323Uncharacterized protein. (392 aa)
CDV56_108963Uncharacterized protein. (472 aa)
CDV56_107524Uncharacterized protein. (811 aa)
CDV56_104804Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (518 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (814 aa)
CDV56_109523Deacetylase sirtuin-type domain-containing protein. (504 aa)
CDV56_108616Uncharacterized protein. (970 aa)
Your Current Organism:
Aspergillus thermomutatus
NCBI taxonomy Id: 41047
Other names: A. thermomutatus, Aspergillus fischeri var. thermomutatus, CBS 208.92, NRRL 20748, Neosartorya pseudofischeri
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