75 items (Aspergillus thermomutatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDV56_101138	Uncharacterized protein. (284 aa)
	CDV56_102673	FHA domain-containing protein. (570 aa)
	CDV56_103166	Uncharacterized protein. (458 aa)
	CDV56_107656	Uncharacterized protein. (387 aa)
	CDV56_107466	Protein kinase domain-containing protein. (817 aa)
	CDV56_109306	AAA domain-containing protein. (355 aa)
	CDV56_106139	Protein kinase domain-containing protein. (597 aa)
	CDV56_106948	Uncharacterized protein. (532 aa)
	CDV56_103758	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (249 aa)
	CDV56_104949	FHA domain-containing protein. (728 aa)
	CDV56_104502	DNA helicase; Belongs to the MCM family. (1023 aa)
	CDV56_107847	Uncharacterized protein. (756 aa)
	HAL4	Pkinase-domain-containing protein. (542 aa)
	CDV56_105152	Uncharacterized protein. (408 aa)
	CDV56_102900	DNA helicase; Belongs to the MCM family. (957 aa)
	CDV56_107742	DNA helicase; Belongs to the MCM family. (889 aa)
	MCM5	DNA helicase; Belongs to the MCM family. (719 aa)
	CDV56_108412	Uncharacterized protein. (442 aa)
	CDV56_105978	Uncharacterized protein. (145 aa)
	CDV56_106383	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (261 aa)
	CDV56_105584	MRC1 domain-containing protein. (1282 aa)
	CDV56_107177	DBF4-type domain-containing protein. (651 aa)
	CDV56_103171	Protein kinase domain-containing protein. (506 aa)
	CDV56_103424	AAA domain-containing protein. (376 aa)
	CDV56_102326	DUF1767 domain-containing protein. (249 aa)
	CDV56_106589	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2061 aa)
	HTB1	Histone H2B; Belongs to the histone H2B family. (140 aa)
	CDV56_106148	Uncharacterized protein. (814 aa)
	CDV56_100918	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (603 aa)
	CDV56_103939	C2H2-type domain-containing protein. (1498 aa)
	PHO85	Negative regulator of the PHO system; Belongs to the protein kinase superfamily. (388 aa)
	CDV56_105493	Rhodanese domain-containing protein. (560 aa)
	CDV56_103111	Uncharacterized protein. (648 aa)
	CDV56_102258	AAA domain-containing protein. (706 aa)
	CDV56_102626	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (323 aa)
	CDV56_101882	ORC_WH_C domain-containing protein. (699 aa)
	CDV56_103066	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (804 aa)
	RFC4	Replication factor C subunit 4. (352 aa)
	CDV56_103122	RPA_C domain-containing protein. (279 aa)
	MCM2	DNA helicase; Belongs to the MCM family. (896 aa)
	CDV56_101764	Checkpoint protein; Belongs to the HUS1 family. (328 aa)
	CDV56_101055	Uncharacterized protein. (707 aa)
	CDV56_103480	Uncharacterized protein. (841 aa)
	CDV56_100580	Uncharacterized protein. (154 aa)
	CDV56_100065	Uncharacterized protein. (182 aa)
	CDV56_100206	CCHC-type domain-containing protein. (292 aa)
	CDV56_100941	Uncharacterized protein. (501 aa)
	CDV56_100638	Uncharacterized protein. (108 aa)
	CDV56_100897	Uncharacterized protein. (153 aa)
	CDV56_102098	14_3_3 domain-containing protein. (381 aa)
	CDV56_100316	Uncharacterized protein. (130 aa)
	CDV56_100197	Uncharacterized protein. (942 aa)
	CDV56_101253	Uncharacterized protein. (778 aa)
	CDV56_100022	Helicase ATP-binding domain-containing protein. (256 aa)
	CDV56_100768	Uncharacterized protein. (238 aa)
	CDV56_100496	Uncharacterized protein. (299 aa)
	CDV56_108870	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (639 aa)
	CDV56_104132	TPR_REGION domain-containing protein. (408 aa)
	CDV56_109222	Uncharacterized protein. (381 aa)
	CDV56_107407	3'-5' exonuclease domain-containing protein. (349 aa)
	CDV56_105475	FHA domain-containing protein. (744 aa)
	CDV56_107943	Cell division control protein; Belongs to the CDC6/cdc18 family. (638 aa)
	CDV56_107613	Uncharacterized protein. (718 aa)
	CDV56_102353	Uncharacterized protein. (396 aa)
	CDV56_108442	Zf-primase domain-containing protein. (805 aa)
	CDV56_109232	Uncharacterized protein. (77 aa)
	CDV56_109178	Protein kinase domain-containing protein. (385 aa)
	CDV56_104030	AAA_16 domain-containing protein. (542 aa)
	CDV56_106188	Uncharacterized protein. (798 aa)
	CDV56_108326	Uncharacterized protein. (1232 aa)
	CDV56_104903	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (423 aa)
	CDV56_107814	zf-GRF domain-containing protein. (333 aa)
	RFC2	Subunit of heteropentameric Replication factor C (RF-C). (392 aa)
	CDV56_109410	Uncharacterized protein. (860 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (814 aa)

Your Current Organism:

Aspergillus thermomutatus

NCBI taxonomy Id: 41047
Other names: A. thermomutatus, Aspergillus fischeri var. thermomutatus, CBS 208.92, NRRL 20748, Neosartorya pseudofischeri

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDV56_100022	CDV56_100580	A0A397FWH0	A0A397G4I3	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.513
CDV56_100022	CDV56_100918	A0A397FWH0	A0A397GK99	Helicase ATP-binding domain-containing protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.809
CDV56_100022	CDV56_101764	A0A397FWH0	A0A397G7I6	Helicase ATP-binding domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.720
CDV56_100022	CDV56_102326	A0A397FWH0	A0A397GQG7	Helicase ATP-binding domain-containing protein.	DUF1767 domain-containing protein.	0.814
CDV56_100022	CDV56_102626	A0A397FWH0	A0A397GAL8	Helicase ATP-binding domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.486
CDV56_100022	CDV56_102900	A0A397FWH0	A0A397H9P4	Helicase ATP-binding domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.428
CDV56_100022	CDV56_103066	A0A397FWH0	A0A397G9M2	Helicase ATP-binding domain-containing protein.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.403
CDV56_100022	CDV56_103111	A0A397FWH0	A0A397GGB3	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.486
CDV56_100022	CDV56_103122	A0A397FWH0	A0A397G9A7	Helicase ATP-binding domain-containing protein.	RPA_C domain-containing protein.	0.793
CDV56_100022	CDV56_103166	A0A397FWH0	A0A397HQV1	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.708
CDV56_100022	CDV56_103424	A0A397FWH0	A0A397GV56	Helicase ATP-binding domain-containing protein.	AAA domain-containing protein.	0.686
CDV56_100022	CDV56_103480	A0A397FWH0	A0A397G5K2	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.775
CDV56_100022	CDV56_104502	A0A397FWH0	A0A397HFA8	Helicase ATP-binding domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.445
CDV56_100022	CDV56_105152	A0A397FWH0	A0A397HCK1	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.773
CDV56_100022	CDV56_105584	A0A397FWH0	A0A397GW55	Helicase ATP-binding domain-containing protein.	MRC1 domain-containing protein.	0.488
CDV56_100022	CDV56_106139	A0A397FWH0	A0A397HL99	Helicase ATP-binding domain-containing protein.	Protein kinase domain-containing protein.	0.455
CDV56_100022	CDV56_106188	A0A397FWH0	A0A397HWV5	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.723
CDV56_100022	CDV56_106589	A0A397FWH0	A0A397GQ98	Helicase ATP-binding domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.812
CDV56_100022	CDV56_107407	A0A397FWH0	A0A397I4Z7	Helicase ATP-binding domain-containing protein.	3'-5' exonuclease domain-containing protein.	0.573
CDV56_100022	CDV56_107466	A0A397FWH0	A0A397HNI4	Helicase ATP-binding domain-containing protein.	Protein kinase domain-containing protein.	0.455