(95 nodes) Lysine degradation network (Aspergillus thermomutatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDV56_103848	Uncharacterized protein. (527 aa)
	CDV56_108031	Uncharacterized protein. (195 aa)
	CDV56_107524	Uncharacterized protein. (811 aa)
	CDV56_107229	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (399 aa)
	CDV56_108926	Zn(2)-C6 fungal-type domain-containing protein. (457 aa)
	CDV56_109635	Fungal_trans domain-containing protein. (712 aa)
	CDV56_103240	SET domain-containing protein. (625 aa)
	CDV56_100115	SET domain-containing protein. (558 aa)
	CDV56_106250	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (231 aa)
	CDV56_109632	DAO domain-containing protein. (447 aa)
	CDV56_101834	Uncharacterized protein. (566 aa)
	CDV56_109258	DAO domain-containing protein. (440 aa)
	SET9	Histone-lysine N-methyltransferase set9. (626 aa)
	CDV56_106296	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (493 aa)
	DLD1	Dihydrolipoyl dehydrogenase. (525 aa)
	CDV56_101234	N-acetyltransferase domain-containing protein. (390 aa)
	CDV56_100793	Uncharacterized protein. (416 aa)
	CDV56_100189	Uncharacterized protein. (306 aa)
	CDV56_100222	Uncharacterized protein. (199 aa)
	CDV56_100415	Fungal_trans domain-containing protein. (754 aa)
	CDV56_101105	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (504 aa)
	CDV56_101045	Zn(2)-C6 fungal-type domain-containing protein. (294 aa)
	CDV56_101689	Aldedh domain-containing protein. (884 aa)
	CDV56_100640	SET domain-containing protein. (927 aa)
	CDV56_100782	Uncharacterized protein. (439 aa)
	CDV56_101139	TauD domain-containing protein. (383 aa)
	CDV56_101031	Uncharacterized protein. (312 aa)
	CDV56_100312	Uncharacterized protein. (514 aa)
	CDV56_102254	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (580 aa)
	CDV56_104526	Uncharacterized protein. (117 aa)
	CDV56_102280	AB hydrolase-1 domain-containing protein. (533 aa)
	CDV56_100498	Uncharacterized protein. (773 aa)
	CDV56_102597	Fibronectin type-III domain-containing protein. (1073 aa)
	CDV56_101193	Aldedh domain-containing protein. (496 aa)
	CDV56_101708	Uncharacterized protein. (413 aa)
	ERG10	Erg10, acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (366 aa)
	CDV56_102910	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (294 aa)
	CDV56_100386	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (497 aa)
	CDV56_104320	HTH myb-type domain-containing protein. (914 aa)
	CDV56_101222	Zn(2)-C6 fungal-type domain-containing protein. (676 aa)
	CDV56_102103	Uncharacterized protein. (846 aa)
	CDV56_103720	Myb-like domain-containing protein. (435 aa)
	CDV56_101992	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (483 aa)
	CDV56_106562	Uncharacterized protein. (458 aa)
	CDV56_106570	Uncharacterized protein. (695 aa)
	CDV56_101386	DAO domain-containing protein. (455 aa)
	CDV56_101367	Uncharacterized protein. (1033 aa)
	CDV56_101132	DAO domain-containing protein. (438 aa)
	KGD2	2-oxoglutarate dehydrogenase complex E2 component. (394 aa)
	CDV56_103570	Post-SET domain-containing protein. (175 aa)
	CDV56_105306	Uncharacterized protein. (329 aa)
	CDV56_105521	MHYT domain-containing protein. (782 aa)
	CDV56_103722	Uncharacterized protein. (463 aa)
	CDV56_107516	FMN hydroxy acid dehydrogenase domain-containing protein. (313 aa)
	CDV56_105554	DAO domain-containing protein. (381 aa)
	CDV56_102680	DAO domain-containing protein. (446 aa)
	CDV56_108052	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (501 aa)
	CDV56_107395	Uncharacterized protein. (274 aa)
	CDV56_101525	Protein kinase domain-containing protein. (920 aa)
	CDV56_106453	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (474 aa)
	CDV56_107487	Zn(2)-C6 fungal-type domain-containing protein. (807 aa)
	CDV56_104297	Zn(2)-C6 fungal-type domain-containing protein. (394 aa)
	CDV56_104616	Uncharacterized protein. (431 aa)
	CDV56_108114	Uncharacterized protein. (312 aa)
	CDV56_100758	Zn(2)-C6 fungal-type domain-containing protein. (439 aa)
	CDV56_108057	Uncharacterized protein. (544 aa)
	CDV56_107515	SET domain-containing protein. (829 aa)
	CDV56_104689	Uncharacterized protein. (488 aa)
	SET2	Histone methyltransferase set2; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (971 aa)
	CDV56_108553	Uncharacterized protein. (356 aa)
	LYS3	Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]. (450 aa)
	CDV56_108226	Succinate-semialdehyde dehydrogenase. (500 aa)
	CDV56_100112	Uncharacterized protein. (202 aa)
	CDV56_108501	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (433 aa)
	SET1	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1242 aa)
	CDV56_108703	Succinate-semialdehyde dehydrogenase. (531 aa)
	CDV56_101842	Uncharacterized protein. (354 aa)
	CDV56_108946	PHD domain-containing protein. (608 aa)
	CDV56_104737	Zn(2)-C6 fungal-type domain-containing protein. (454 aa)
	CDV56_107970	Uncharacterized protein. (304 aa)
	CDV56_102441	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (502 aa)
	CDV56_107900	AB hydrolase-1 domain-containing protein. (537 aa)
	CDV56_100345	Aldedh domain-containing protein. (501 aa)
	CDV56_109035	Uncharacterized protein. (285 aa)
	CDV56_108554	Uncharacterized protein. (721 aa)
	DOT1	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (503 aa)
	CDV56_106603	Uncharacterized protein. (388 aa)
	CDV56_106502	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (474 aa)
	CDV56_106920	Uncharacterized protein. (210 aa)
	CDV56_106899	Fungal_trans domain-containing protein. (742 aa)
	CDV56_109155	Aldedh domain-containing protein. (413 aa)
	CDV56_107310	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (497 aa)
	CDV56_108571	Zn(2)-C6 fungal-type domain-containing protein. (484 aa)
	CDV56_105823	SET domain-containing protein. (444 aa)
	CDV56_107969	Aldedh domain-containing protein. (514 aa)

Your Current Organism:

Aspergillus thermomutatus

NCBI taxonomy Id: 41047
Other names: A. thermomutatus, Aspergillus fischeri var. thermomutatus, CBS 208.92, NRRL 20748, Neosartorya pseudofischeri

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDV56_100112	CDV56_102103	A0A397HGG2	A0A397GGY6	Uncharacterized protein.	Uncharacterized protein.	0.629
CDV56_100112	CDV56_105823	A0A397HGG2	A0A397HRX5	Uncharacterized protein.	SET domain-containing protein.	0.481
CDV56_100112	DOT1	A0A397HGG2	A0A397HNY0	Uncharacterized protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.455
CDV56_100112	SET2	A0A397HGG2	A0A397HD42	Uncharacterized protein.	Histone methyltransferase set2; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.458
CDV56_100115	CDV56_100640	A0A397HYP4	A0A397G0N0	SET domain-containing protein.	SET domain-containing protein.	0.533
CDV56_100115	CDV56_102103	A0A397HYP4	A0A397GGY6	SET domain-containing protein.	Uncharacterized protein.	0.502
CDV56_100115	CDV56_103722	A0A397HYP4	A0A397GUZ0	SET domain-containing protein.	Uncharacterized protein.	0.533
CDV56_100115	CDV56_106570	A0A397HYP4	A0A397GIP6	SET domain-containing protein.	Uncharacterized protein.	0.533
CDV56_100115	CDV56_107524	A0A397HYP4	A0A397HTI7	SET domain-containing protein.	Uncharacterized protein.	0.611
CDV56_100115	CDV56_108946	A0A397HYP4	A0A397HIW9	SET domain-containing protein.	PHD domain-containing protein.	0.533
CDV56_100115	DOT1	A0A397HYP4	A0A397HNY0	SET domain-containing protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.672
CDV56_100115	SET1	A0A397HYP4	A0A397HIA4	SET domain-containing protein.	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	0.611
CDV56_100115	SET2	A0A397HYP4	A0A397HD42	SET domain-containing protein.	Histone methyltransferase set2; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.531
CDV56_100115	SET9	A0A397HYP4	A0A397I377	SET domain-containing protein.	Histone-lysine N-methyltransferase set9.	0.476
CDV56_100189	CDV56_100345	A0A397FX76	A0A397HLH2	Uncharacterized protein.	Aldedh domain-containing protein.	0.534
CDV56_100189	CDV56_100386	A0A397FX76	A0A397G9K2	Uncharacterized protein.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.512
CDV56_100189	CDV56_100415	A0A397FX76	A0A397FXF4	Uncharacterized protein.	Fungal_trans domain-containing protein.	0.512
CDV56_100189	CDV56_101105	A0A397FX76	A0A397FYD6	Uncharacterized protein.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.512
CDV56_100189	CDV56_101193	A0A397FX76	A0A397G546	Uncharacterized protein.	Aldedh domain-containing protein.	0.512
CDV56_100189	CDV56_101222	A0A397FX76	A0A397GGA5	Uncharacterized protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.512